organic anion transporter

出典: meddic

有機アニオントランスポーター OAT

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出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2016/01/31 15:47:19」(JST)

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英文文献

  • In vivo selective imaging and inhibition of leukemia stem-like cells using the fluorescent carbocyanine derivative, DiOC5(3).
  • Zhang B1, Shimada Y2, Kuroyanagi J1, Ariyoshi M1, Nomoto T3, Shintou T3, Umemoto N4, Nishimura Y2, Miyazaki T3, Tanaka T5.
  • Biomaterials.Biomaterials.2015 Jun;52:14-25. doi: 10.1016/j.biomaterials.2015.02.009. Epub 2015 Feb 21.
  • Elimination of leukemia stem cells (LSCs) is necessary for the destruction of malignant cell populations. Owing to the very small number of LSCs in leukemia cells, xenotransplantation studies are difficult in terms of functionally and pathophysiologically replicating clinical conditions of cell cult
  • PMID 25818410
  • Gene replacement therapy for genetic hepatocellular jaundice.
  • van Dijk R1, Beuers U, Bosma PJ.
  • Clinical reviews in allergy & immunology.Clin Rev Allergy Immunol.2015 Jun;48(2-3):243-53. doi: 10.1007/s12016-014-8454-7.
  • Jaundice results from the systemic accumulation of bilirubin, the final product of the catabolism of haem. Inherited liver disorders of bilirubin metabolism and transport can result in reduced hepatic uptake, conjugation or biliary secretion of bilirubin. In patients with Rotor syndrome, bilirubin (
  • PMID 25315738
  • Evaluation of cynomolgus monkeys for the identification of endogenous biomarkers for hepatic transporter inhibition and as a translatable model to predict pharmacokinetic interactions with statins in humans.
  • Chu X1, Shih SJ2, Shaw R2, Hentze H2, Chan GH2, Owens K2, Wang S2, Cai X2, Newton D2, Castro-Perez J2, Salituro G2, Palamanda J2, Fernandis A2, Ng CK2, Liaw A2, Savage MJ2, Evers R2.
  • Drug metabolism and disposition: the biological fate of chemicals.Drug Metab Dispos.2015 Jun;43(6):851-63. doi: 10.1124/dmd.115.063347. Epub 2015 Mar 26.
  • Inhibition of hepatic transporters such as organic anion transporting polypeptides (OATPs) 1B can cause drug-drug interactions (DDIs). Determining the impact of perpetrator drugs on the plasma exposure of endogenous substrates for OATP1B could be valuable to assess the risk for DDIs early in drug de
  • PMID 25813937

和文文献

  • The expression of transporter OATP2/OATP8 decreases in undetectable hepatocellular carcinoma by Gd-EOB-MRI in the explanted cirrhotic liver
  • Hidaka Masaaki,Takatsuki Mitsuhisa,Okudaira Sadayuki,Soyama Akihiko,Muraoka Izumi,Tanaka Takayuki,Yamaguchi Izumi,Hara Takanobu,Miyaaki Hisamitsu,Ichikawa Tatsuki,Hayashi Tomayoshi,Sakamoto Ichiro,Nakao Kazuhiko,Kuroki Tamotsu,Kanematsu Takashi,Eguchi Susumu
  • Hepatology International 7(2), 655-661, 2013-06-00
  • … Purpose: The aim of this study is to evaluate the detectability of hepatocellular carcinoma (HCC) in the explanted cirrhotic liver using gadoxetic acid-enhanced magnetic resonance imaging (Gd-EOB-MRI) and the degree of organic anion transporter OATP2/OATP8 (OATP1B1/1B3) HCC which could not be preoperatively detected by multi-detector computed tomography (MD-CT) and Gd-EOB-MRI. … The transporter of OATP2/OATP8 was less expressed in the preoperatively undetectable HCCs. …
  • NAID 120005311953
  • Sustained Repression and Translocation of NTCP and Expression of MRP4 for Cholestasis after Rat 90% Partial Hepatectomy
  • Miura Takuya,Kimura Norihisa,Yamada Toshiyuki,Shimizu Takeshi,Nanashima Naoki,Yamana Daisuke,Hakamada Kenichi,Tsuchida Shigeki
  • 弘前医学 64(Supplement), S99-S106, 2013-04-02
  • … Background/Aims: To clarify the mechanism of persistent cholestasis after massive hepatectomy, the relationship between such cholestasis and the expression and localization of organic anion transporters for bile acids was examined in a rat model.Methods: Male Sprague-Dawley rats were subjected to 90% hepatectomy, and tissues were harvested on 0, 1, 3, and 7 days for microarray analysis, the quantitative real-time polymerase chain reaction (RT-PCR), Western blotting and immunohistochemistry to examine the expression of …
  • NAID 120005230059
  • Active intestinal absorption of fluoroquinolone antibacterial agent ciprofloxacin by organic anion transporting polypeptide, Oatp1a5
  • Arakawa Hiroshi,Shirasaka Yoshiyuki,Haga Makoto,Nakanishi Takeo,Tamai Ikumi
  • Biopharmaceutics and Drug Disposition 33(6), 332-341, 2012-09-00
  • … It has been that several fluoroquinolones are substrates of organic anion transporter polypeptides OATP1A2 expressed in human intestine derived Caco-2 cells. …
  • NAID 120004997009

関連リンク

Buy Organic Anion Transporter (OAT) family antibodies from Santa Cruz. Select an OAT antibody from 8 polyclonal antibodies. OAT si/shRNA products also available. ... Santa Cruz Biotechnology, Inc. offers a broad range of Organic ...
Human Kidney (frozen section) <Reference> 1. Sekine T., Cha S.H., Kanai Y.and Endou H.:Molecular biology of multispecific organic anion transporter family (OAT family). Clin.Exp.Nephlrol.3.237-243,1999 2. Sekine T., Cha S.H.and ...

関連画像

 Organic Anion; Organic Anion TransportTransporter-mediated Drug–Drug Organic Anion Transporter 1 (OAT1)View Large | Save Figure | Download Slide Organic anion transporter 1Unfortunately we are unable to provide


★リンクテーブル★
リンク元有機アニオントランスポーター」「OAT
拡張検索organic anion transporter 1」「organic anion transporter 2」「organic anion transporters
関連記事organic」「transport」「organ」「transporter」「anion

有機アニオントランスポーター」

  [★]

organic anion transporter, OATorganic anion transporters, OATs
有機アニオン輸送体
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OAT」

  [★] 有機アニオントランスポーター organic anion transporter


organic anion transporter 1」

  [★]

有機アニオン輸送体1、有機アニオントランス・ーター1

OAT1、organic anion transport protein 1

organic anion transporter 2」

  [★]


organic anion transporters」

  [★] 有機アニオントランスポーター OATs


organic」

  [★]

  • adj.
  • 有機物の、有機の、有機的な、器質性の、器質的な
organic compoundorganic matterorganizedorgano

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「simple and healthful and close to nature; "an organic lifestyle"」

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「a fertilizer that is derived from animal or vegetable matter」
organic fertilizer, organic fertiliser

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「有機体の,生物の,生物から生じた / (動植物の)器官の / 有機肥料を用いる(を用いて育った)・有機的な,組織的な,系統的な・有機質の」

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「being or relating to or derived from or having properties characteristic of living organisms; "organic life"; "organic growth"; "organic remains found in rock"」

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「involving or affecting physiology or bodily organs; "an organic disease"」

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「of or relating to foodstuff grown or raised without synthetic fertilizers or pesticides or hormones; "organic eggs"; "organic vegetables"; "organic chicken"」

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「relating or belonging to the class of chemical compounds having a carbon basis; "hydrocarbons are organic compounds"」


transport」

  [★]

  • n.
  • v.
  • 輸送する、運搬する、運ぶ
bringcarriagecarryconveydeliveryshiptraffictraffickingtransportation

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「move something or somebody around; usually over long distances」

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「an exchange of molecules (and their kinetic energy and momentum) across the boundary between adjacent layers of a fluid or across cell membranes」

PrepTutorEJDIC   license prepejdic

「(ある場所からある場所へ)…‘を'『輸送する』,運搬する《+名+from+名+to+名》 / 《文》《受動態で》(…で)…‘を'夢中にする,有頂天にする《+名+with+名》 / 〈罪人〉‘を'流刑にする / 〈U〉輸送,運送,輸送(交通)機関(transportation) / 〈C〉(軍隊や軍需品を運ぶ)輸送船,輸送機」

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「move while supporting, either in a vehicle or in one''s hands or on one''s body; "You must carry your camping gear"; "carry the suitcases to the car"; "This train is carrying nuclear waste"; "These pipes carry waste water into the river"」
carry

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「transport commercially」
send, ship


organ」

  [★]

  • n.
  • 臓器、器官


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「wind instrument whose sound is produced by means of pipes arranged in sets supplied with air from a bellows and controlled from a large complex musical keyboard」
pipe organ

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「a fully differentiated structural and functional unit in an animal that is specialized for some particular function」

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「a government agency or instrument devoted to the performance of some specific function; "The Census Bureau is an organ of the Commerce Department"」

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「a periodical that is published by a special interest group; "the organ of the communist party"」

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「『オルガン』,パイプオルガン(pipe organ),リードオルガン(reed organ),電子オルガン(electronic organ),手回しオルガン(barrel organ) / (動植物の)『器官』 / (政党・会社などの)機関誌,機関紙 / 《しばしば複数形で》(行動・実施などの)組織,機関」


transporter」

  [★] トランスポーター

translocatortransport proteintransporter protein

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「自動車運搬用大型トラック」

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「a long truck for carrying motor vehicles」
car transporter

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「a crane for moving material with dispatch as in loading and unloading ships」


anion」

  [★] アニオン

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「a negatively charged ion」

PrepTutorEJDIC   license prepejdic

「陰イオン」




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