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出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2013/07/26 00:39:30」(JST)

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  • A switch between one- and two-electron chemistry of the human flavoprotein iodotyrosine deiodinase is controlled by substrate.
  • Hu J1, Chuenchor W1, Rokita SE2.
  • The Journal of biological chemistry.J Biol Chem.2015 Jan 2;290(1):590-600. doi: 10.1074/jbc.M114.605964. Epub 2014 Nov 13.
  • Reductive dehalogenation is not typical of aerobic organisms but plays a significant role in iodide homeostasis and thyroid activity. The flavoprotein iodotyrosine deiodinase (IYD) is responsible for iodide salvage by reductive deiodination of the iodotyrosine derivatives formed as byproducts of thy
  • PMID 25395621
  • Ion pair hollow fiber liquid-liquid-liquid microextraction combined with capillary electrophoresis-ultraviolet detection for the determination of thyroid hormones in human serum.
  • Li P1, Hu B2, He M1, Chen B1.
  • Journal of chromatography. A.J Chromatogr A.2014 Aug 22;1356:23-31. doi: 10.1016/j.chroma.2014.06.046. Epub 2014 Jun 21.
  • In this study, a novel, inexpensive, sensitive and selective analytical method that combines ion pair hollow fiber liquid-liquid-liquid microextraction (IP-HF-LLLME) with capillary electrophoresis-ultraviolet detection (CE-UV) was developed for the simultaneous determination of six thyroid hormones
  • PMID 24997114
  • Hormonogenic donor Tyr2522 of bovine thyroglobulin. Insight into preferential T3 formation at thyroglobulin carboxyl terminus at low iodination level.
  • Cetrangolo GP1, Arcaro A2, Lepore A3, Graf M4, Mamone G5, Ferranti P6, Palumbo G7, Gentile F8.
  • Biochemical and biophysical research communications.Biochem Biophys Res Commun.2014 Jul 18;450(1):488-93. doi: 10.1016/j.bbrc.2014.05.144. Epub 2014 Jun 6.
  • A tryptic fragment (b5TR,NR), encompassing residues 2515-2750, was isolated from a low-iodine (0.26% by mass) bovine thyroglobulin, by limited proteolysis with trypsin and preparative, continuous-elution SDS-PAGE. The fragment was digested with Asp-N endoproteinase and analyzed by reverse-phase HPLC
  • PMID 24911556


  • サイログロブリンのホルモン合成部位の抗原性 : ヨウ素化に伴う抗原性の変化
  • 星岡 明,河野 陽一,勝木 利行,下条 直樹,坂田 茂樹,樽谷 修,丸山 直記,稲垣 好昌,横地 高志,新美 仁男
  • アレルギー 43(2-1), 152-158, 1994-02-28
  • … 以上より, ホルモン合成の過程でTgのホルモン合成部位のチロシン残基にヨウ素が結合し, monoiodotyrosine(MIT)あるいはdiiodotyrosine(DIT)残基が作られることが, 抗Tg自己抗体の産生や甲状腺炎の発症に直接関与していることが強く示唆された. …
  • NAID 110002422455
  • Partial Characterization of the Iodination Site in D1 Protein of Manganese-Retaining and Manganese-Depleted Photosystem II Membranes
  • Ikeuchi Masahiko,Inoue Yorinao
  • Plant and cell physiology 29(4), 695-705, 1988-06
  • … Amino acid analysis revealed that monoiodotyrosine is the sole amino acid iodinated, and peptide mapping analysis showed that the iodination site is located between proline-141 and methionine-172 of D1 in both samples. …
  • NAID 110003719398
  • <原著>抗ヒトサイログロブリン単クローン抗体の基礎的研究およびその臨床応用(1) : 抗ヒトサイログロブリン単クローン抗体の作製および特異性の検討
  • 大野 恭裕
  • 近畿大学医学雑誌 12(1), 181-192, 1987-03-25
  • … Every monoclonal antibody did not show cross reaction with diiodotyrosine, monoiodotyrosine, triiodothyronine and L-thyroxine. …
  • NAID 110000060092


mon·o·i·o·do·ty·ro·sine (MIT), (mon'ō-ī-ō'dō-tī'rō-sēn), An intermediate in thyroid hormone synthesis. monoiodotyrosine /mono·io·do·ty·ro·sine/ (-i-o″do-ti´ro-sēn) an iodinated amino acid intermediate in the synthesis of thyroxine and ...
Monoiodotyrosine information including symptoms, causes, diseases, symptoms, treatments, and other medical and health issues. ... Introduction: Monoiodotyrosine Description of Monoiodotyrosine Monoiodotyrosine: A product ...


Monoiodotyrosine )Synonyms: MonoiodotyrosineMIT means MonoiodotyrosineMonoiodotyrosine (Iodotyrosine)4BIOSYNTHESIS OF THYROID HORMONESDescription Monoiodotyrosine.png






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「tyrosine with iodine added」