monoamine oxidase B

出典: meddic


amine oxidaseMAOMAO-AMAO-Bmonoamine oxidasemonoamine oxidase A

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出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2016/03/01 21:09:14」(JST)

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  • The evidence-based pharmacotherapy of social anxiety disorder.
  • Blanco C, Bragdon LB, Schneier FR, Liebowitz MR.SourceDepartment of Psychiatry of Columbia College of Physicians and Surgeons and the New York State Psychiatric Institute, New York, NY, USA.
  • The international journal of neuropsychopharmacology / official scientific journal of the Collegium Internationale Neuropsychopharmacologicum (CINP).Int J Neuropsychopharmacol.2013 Feb;16(1):235-49. doi: 10.1017/S1461145712000119. Epub 2012 Mar 21.
  • Social anxiety disorder (SAD) is a highly prevalent and often disabling disorder. This paper reviews the pharmacological treatment of SAD based on published placebo-controlled studies and published meta-analyses. It addresses three specific questions: What is the first-line pharmacological treatment
  • PMID 22436306
  • Selective inhibition of monoamine oxidase A or B reduces striatal oxidative stress in rats with partial depletion of the nigro-striatal dopaminergic pathway.
  • Aluf Y, Vaya J, Khatib S, Loboda Y, Finberg JP.SourceDepartment of Molecular Pharmacology, Rappaport Medical Faculty, Technion, Haifa, Israel; Oxidative Stress Research Laboratory, Migal-Galilee Technology Center, Kiryat Shmona, and Tel Hai College, Israel.
  • Neuropharmacology.Neuropharmacology.2013 Feb;65:48-57. doi: 10.1016/j.neuropharm.2012.08.023. Epub 2012 Sep 7.
  • Partial lesion (50%) of the nigro-striatal dopaminergic pathway induces compensatory increase in dopamine release from the remaining neurons and increased extracellular oxidative stress (OS(-ec)) in the striatum. The present study was designed to explore the role of monoamine oxidase types A and B (
  • PMID 22982254
  • Association study of DRD2 and MAOA genes with subtyped alcoholism comorbid with bipolar disorder in Han Chinese.
  • Hu MC, Lee SY, Wang TY, Chen SL, Chang YH, Chen SH, Chu CH, Wang CL, Lee IH, Yeh TL, Yang YK, Lu RB.SourceInstitute of Behavioral Medicine, National Cheng Kung University, Tainan, Taiwan.
  • Progress in neuro-psychopharmacology & biological psychiatry.Prog Neuropsychopharmacol Biol Psychiatry.2013 Jan 10;40:144-8. doi: 10.1016/j.pnpbp.2012.09.014. Epub 2012 Oct 5.
  • BACKGROUND: Several studies have hypothesized that genes involved in the dopamine system, including dopamine type-2 receptor (DRD2)-related TaqIA polymorphism and monoamine oxidase-A upstream variable number tandem repeat (uVNTR), may be associated with alcoholism. But their results were contradicto
  • PMID 23044341


  • Spatio-temporal regulation of the formation of the somatosensory system
  • Kawasaki Hiroshi
  • Development Growth and Differentiation 57(3), 193-199, 2015-04-01
  • … Glutamatergic receptors such as the NMDA receptor and mGluR5, and molecules related to serotonin such as serotonin transporter and monoamine oxidase A are essential for the formation of barrels. …
  • NAID 120005613962
  • Shoot cultures of Hoppea fastigiata (Griseb.) C.B. Clarke as potential source of neuroprotective xanthones
  • Moon Utkarsh Ravindra,Sircar Debabrata,Barthwal Ritu [他]
  • Journal of natural medicines 69(3), 375-386, 2015
  • NAID 40020494397
  • Synthesis and in Vitro Evaluation of the Antitubercular and Antibacterial Activity of Novel Oxazolidinones Bearing Octahydrocyclopenta[c]pyrrol-2-yl Moieties
  • Bhattarai Deepak,Lee Ju-hyeon,Seo Seon Hee,Nam Ghilsoo,Choo Hyunah,Kang Soon Bang,Kwak Jin-Hwan,Oh Taegwon,Cho Sang-Nae,Pae Ae Nim,Kim Eunice Eunkyeong,Jeong Nakcheol,Keum Gyochang
  • Chemical and Pharmaceutical Bulletin 62(12), 1214-1224, 2014
  • … Selected compounds with high antimicrobial activity showed good human microsomal stability and low CYP isozyme and monoamine oxidase (MAO) inhibition. …
  • NAID 130004693782


Monoamine oxidase B, also known as MAOB, is an enzyme that in humans is encoded by the MAOB gene. ... MAO-A is involved in the metabolism of serotonin, noradrenaline and dopamine where as MAO-B metabolises the dopamine ...
人間においては、MAO-AとMAO-Bの2種類のモノアミン酸化酵素が存在する。双方とも 神経系やアストログリア(星状膠細胞)において存在し、MAO-Aは肝臓や胃腸、胎盤にも 存在する。中枢神経系の他では、MAO-Bは主に血液血小板に存在する。



先読みMAO」「monoamine oxidase
リンク元MAOB」「monoamine oxidase A」「モノアミンオキシダーゼB
関連記事B」「monoamine」「oxidase」「monoamine oxidase」「monoamines


  [★] モノアミンオキシダーゼ

Monoamine oxidase
monoamine oxidase

monoamine oxidase」





monoamine oxidase B,MAO-B

monoamine oxidase A」



amine oxidaseMAOMAO-AMAO-Bmonoamine oxidasemonoamine oxidase B



monoamine oxidase B



  • Mg2+存在下でC3, B, Dが反応してC3bBbとなり、これがC3転換酵素(C3bBb)あるいはC5転換酵素(C3bBb3b)を形成する。これらはP(properdin)と結合して活性化し、それぞれC3、C5を活性化する

WordNet   license wordnet

「the 2nd letter of the Roman alphabet」

WordNet   license wordnet

「the blood group whose red cells carry the B antigen」
type B, group B


  [★] モノアミン

WordNet   license wordnet

「a molecule containing one amine group (especially one that is a neurotransmitter)」


  [★] オキシダーゼ

WordNet   license wordnet

「any of the enzymes that catalyze biological oxidation」

monoamine oxidase」





See Biogenic amines