memantine

出典: meddic

メマンチン

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出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2015/04/23 21:55:09」(JST)

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出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2015/05/25 14:08:24」(JST)

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出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2016/03/05 07:34:37」(JST)

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出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2016/04/11 02:25:47」(JST)

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出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2016/05/20 03:49:16」(JST)

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英文文献

  • The basal forebrain cholinergic system in aging and dementia. Rescuing cholinergic neurons from neurotoxic amyloid-β42 with memantine.
  • Nyakas C, Granic I, Halmy LG, Banerjee P, Luiten PG.SourceNeuropsychopharmacological Research Group of Hungarian Academy of Sciences and Semmelweis University, Budapest, Hungary; Department of Molecular Neurobiology, University of Groningen, Groningen, The Netherlands.
  • Behavioural brain research.Behav Brain Res.2011 Aug 10;221(2):594-603. Epub 2010 May 27.
  • The dysfunction and loss of basal forebrain cholinergic neurons and their cortical projections are among the earliest pathological events in the pathogenesis of Alzheimer's disease (AD). The evidence pointing to cholinergic impairments come from studies that report a decline in the activity of choli
  • PMID 20553766
  • Effects of long-term memantine on memory and neuropathology in Ts65Dn mice, a model for Down syndrome.
  • Lockrow J, Boger H, Bimonte-Nelson H, Granholm AC.SourceDepartment of Neuroscience, Center on Aging, Medical University of South Carolina, 173 Ashley Avenue, Ste 410D, Charleston, SC 29425, USA.
  • Behavioural brain research.Behav Brain Res.2011 Aug 10;221(2):610-22. Epub 2010 Apr 2.
  • Memantine is a partial NMDA receptor antagonist that has been shown to improve learning and memory in several animal models, and is approved for the treatment of Alzheimer's disease (AD). Chronic treatments using memantine in animal models of Alzheimer's disease show disease-modifying effects and su
  • PMID 20363261

和文文献

  • 新規NMDA受容体拮抗剤であるメマンチン塩酸塩の中等度から高度アルツハイマー型認知症に対する第3相試験--有効性および安全性の検討
  • 中村 祐,本間 昭,北村 伸 [他]
  • 老年精神医学雑誌 22(4), 464-473, 2011-04
  • NAID 40018785832
  • 新規NMDA受容体拮抗剤であるメマンチン塩酸塩の中等度から高度アルツハイマー型認知症に対する後期第2相試験--有効性・安全性および推奨用量の検討
  • 北村 伸,本間 昭,中村 祐 [他]
  • 老年精神医学雑誌 22(4), 453-463, 2011-04
  • NAID 40018785831

関連リンク

Medical use [edit] Memantine is approved by the U.S. F.D.A and the European Medicines Agency for treatment of moderate-to-severe Alzheimer's disease, [5] and has now received a limited recommendation by the UK's National ...
On this website healthcare professionals find detailed information about memantine and Alzheimer disease. Only healthcare professionals can be given access to specific medical information of memantine.com. Please use the . ...
... Mr. Baron was listening to the radio and heard a news report about an Alzheimer's drug, memantine. The drug blocks a brain chemical, glutamate, which has been implicated in nerve cell death. A new study found that it It is ...

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