WordNet

used of flowers having more than the usual number of petals in crowded or overlapping arrangements; "double chrysanthemums have many rows of petals and are usually spherical or hemispherical"
increase twofold; "The population doubled within 50 years" (同)duplicate
a base hit on which the batter stops safely at second base; "he hit a double to deep centerfield" (同)two-base hit, two-bagger, two-baser
someone who closely resembles a famous person (especially an actor); "he could be Gingrichs double"; "shes the very image of her mother" (同)image, look-alike
a stand-in for movie stars to perform dangerous stunts; "his first job in Hollywood was as a double for Clark Gable" (同)stunt man, stunt woman
a quantity that is twice as great as another; "36 is the double of 18"
twice as great or many; "ate a double portion"; "the dose is doubled"; "a twofold increase" (同)doubled, twofold, two-fold
consisting of or involving two parts or components usually in pairs; "an egg with a double yolk"; "a double (binary) star"; "double doors"; "dual controls for pilot and copilot"; "duple (or double) time consists of two (or a multiple of two) beats to a measure" (同)dual, duple
having more than one decidedly dissimilar aspects or qualities; "a double (or dual) role for an actor"; "the office of a clergyman is twofold; public preaching and private influence"- R.W.Emerson; "every episode has its double and treble meaning"-Frederick Harrison (同)dual, twofold, two-fold, treble, threefold, three-fold
having two meanings with intent to deceive; "a sly double meaning"; "spoke with forked tongue" (同)forked
bridge: make a demand for (a card or suit)
do double duty; serve two purposes or have two functions; "She doubles as his wife and secretary"
downward and forward; "he was bent double with pain"
hit a two-base hit
large enough for two; "a double bed"; "a double room"
two together; "some people sleep better double"
prepare or position for action or operation; "lay a fire"; "lay the foundation for a new health care plan"
put in a horizontal position; "lay the books on the table"; "lay the patient carefully onto the bed" (同)put down, repose
impose as a duty, burden, or punishment; "lay a responsibility on someone"
lay eggs; "This hen doesnt lay"
not of or from a profession; "a lay opinion as to the cause of the disease"
make or form a layer; "layer the different colored sands"
single thickness of usually some homogeneous substance; "slices of hard-boiled egg on a bed of spinach" (同)bed
a hen that lays eggs
thin structure composed of a single thickness of cells
a relatively thin sheetlike expanse or region lying over or under another
(botany) either of the two parts of a bilabiate corolla or calyx
either the outer margin or the inner margin of the aperture of a gastropods shell
either of two fleshy folds of tissue that surround the mouth and play a role in speaking
an oily organic compound insoluble in water but soluble in organic solvents; essential structural component of living cells (along with proteins and carbohydrates) (同)lipide, lipoid

PrepTutorEJDIC

(数量・強さ・重さ・価値などが)『2倍の』,倍の / 『二重の』,二様の;複の,対の,2人用の / 表裏のある,二心ある / (意味が)二様にとれる,あいまいな / (花が)八重の,重弁の / 『2倍に』,2倍だけ(twice) / 二重に,二様に / 対をなして,二人いっしょに / 〈U〉『2倍』[の数量・価額など] / 〈C〉2倍のもの / 〈C〉よく似た人(物),生き写し / 〈C〉(映画の)代役 / 《複数形》《単数扱い》(テニスなどの)ダブルス / 〈C〉(獲物が追っ手を逃れるときなどの)逆走,急転回 / 〈C〉2塁打 / 〈C〉(ブリッジの点の)倍加 / 〈C〉(競馬・ドッグレースの)重勝式のかけ,複式 / …‘を'『2倍にする』 / …‘を'『二つ折りにする』 / …‘の'2倍の数(量)がある / 〈二役〉‘を'ひとりで演ずる / 〈船が〉〈岬〉‘を'回る / 『2倍になる』 / (…の役を)兼ねる《+『as』+『名』》 / (急に)取って返す,逆戻りする《+『back』》 / 二つ折りになる / (ブリッジで)相手のせり高を倍加する / 2塁打を打つ
《場所の副詞[句]を伴って》‘を'『置く』,横たえる / ‘を'『きちんと置く』(並べる),〈土台など〉‘を'すえる,〈鉄道など〉‘を'敷設する / …‘を'『用意する』,準備する / (…に)〈身体の一部〉‘を'置く,つける《+『名』+『on』(『to』)+『名』》 / (…に)〈信頼・愛情〉‘を'置く,寄せる,託す;〈強調・重要性など〉‘を'置く《+『名』+『on』+『名』》 / 〈ほこり・波・風など〉‘を'押さえる,〈恐れ亡霊など〉‘を'静める,なだめる / 〈卵〉‘を'産む / 〈かけ〉‘を'する;(…に)〈金〉‘を'かける《+『名』+『on』+『名』》 / (…に)〈税・罰金・義務など〉‘を'課する,〈重荷・責任など〉‘を'負わせる《+『名』+『on』(『upon』)+『名』》 / 〈悪事など〉‘を'(…の)せいにする《+『名』+『against』(『to』)+『名』》 / 《状態を表す副詩[句]を伴って》(特によくない状態に)…‘を'『置く』,する / (…に)〈権利の主張・報告など〉‘を'提出する,申し出る《+『名』+『before』(『to』)+『名』》 / (…で)…‘の'表面をおおう《+『名』+『with』+『名』》;(…に)…‘を'広げる《+『名』+『on』+『名』》 / 卵を産む / 位置,配置,地形,地勢
lieの過去形
(歌うために書かれた)短い物語詩 / 《詩》(一般に)歌,調べ
(僧職にある人に対して)俗人の / (専門家に対して)しろうとの,門外漢の
《複合語を作って》(物を)積む人(物),置く人(物) / 卵を産む鶏・層;(ペンキなどの)一塗り;一皮 / (園芸で)取り木 / …‘を'層にする / 〈植物〉‘を'取り木する
〈C〉『くちびる』,口もと / 《複数形で》(発音器官としての)くちびる,口 / 〈U〉《俗》生意気な言葉 / 〈C〉(容器などの)口,へり,縁;(峡谷・火山などの)口 / 〈C〉(植物の)唇弁(しんべん)
脂質,あぶら

UpToDate Contents

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1. 腎移植後の脂質異常 lipid abnormalities after renal transplantation
2. フィブラート系薬剤による脂質低下 lipid lowering with fibric acid derivatives
3. スタチン系およびフィブラート系以外の薬剤による脂質低下 lipid lowering with drugs other than statins and fibrates
4. 食事または栄養補助食品による脂質低下 lipid lowering with diet or dietary supplements
5. LDLコレステロール代謝の遺伝性疾患 inherited disorders of ldl cholesterol metabolism

English Journal

Amyloid β-peptide insertion in liposomes containing GM1-cholesterol domains.

Nicastro MC1, Spigolon D2, Librizzi F3, Moran O4, Ortore MG5, Bulone D3, Biagio PL3, Carrotta R6.
Biophysical chemistry.Biophys Chem.2016 Jan;208:9-16. doi: 10.1016/j.bpc.2015.07.010. Epub 2015 Jul 31.
Neuronal membrane damage is related to the early impairments appearing in Alzheimer's disease due to the interaction of the amyloid β-peptide (Aβ) with the phospholipid bilayer. In particular, the ganglioside GM1, present with cholesterol in lipid rafts, seems to be able to initiate Aβ aggregatio
PMID 26259785

Amphipathic alpha-helices and putative cholesterol binding domains of the influenza virus matrix M1 protein are crucial for virion structure organisation.

Tsfasman T1, Kost V2, Markushin S2, Lotte V2, Koptiaeva I2, Bogacheva E3, Baratova L4, Radyukhin V5.
Virus research.Virus Res.2015 Dec 2;210:114-8. doi: 10.1016/j.virusres.2015.07.017. Epub 2015 Jul 23.
The influenza virus matrix M1 protein is an amphitropic membrane-associated protein, forming the matrix layer immediately beneath the virus raft membrane, thereby ensuring the proper structure of the influenza virion. The objective of this study was to elucidate M1 fine structural characteristics, w
PMID 26211889

Two polar residues within C-terminal domain of M1 are critical for the formation of influenza A Virions.

Zhang K1, Wang Z2,3, Fan GZ2, Wang J4, Gao S1, Li Y1, Sun L1, Yin CC2, Liu WJ1,5.
Cellular microbiology.Cell Microbiol.2015 Nov;17(11):1583-93. doi: 10.1111/cmi.12457. Epub 2015 May 29.
The matrix protein 1 (M1) is the most abundant structural protein in influenza A virus particles. It oligomerizes to form the matrix layer under the lipid membrane, sustaining stabilization of the morphology of the virion. The present study indicates that M1 forms oligomers based on a fourfold symme
PMID 25939747

Japanese Journal

Elucidating the Effects of Cholesterol on the Molecular Packing of Double-chained Cationic Lipid Langmuir Monolayers by Infrared Reflectionabsorption Spectroscopy

,
Journal of Oleo Science advpub(0), 2015
… To explore the mechanisms involved in adjusting the bilayer structure by cholesterol, the molecular packing behavior in a mimic outer layer of cationic dialkyldimethylammonium bromide (DXDAB)/cholesterol vesicular bilayer was investigated by the Langmuir monolayer approach with infrared reflection-absorption spectroscopy (IRRAS). …
NAID 130004800150

Electrostatic Control of Artificial Cell Membrane Spreading by Tuning the Thickness of an Electric Double Layer in a Nanogap

KASHIMURA Yoshiaki,FURUKAWA Kazuaki,TORIMITSU Keiichi
IEICE transactions on electronics 96(3), 344-347, 2013-03-01
NAID 10031167359

Electrostatic Control of Artificial Cell Membrane Spreading by Tuning the Thickness of an Electric Double Layer in a Nanogap

, ,
IEICE Transactions on Electronics E96.C(3), 344-347, 2013
… When we apply a voltage to a supported lipid bilayer self-spreading through a nanometer-scale gap (nanogap), the effects can be divided into two types. … Namely, the lipid bilayer passes through a nanogap without any stagnation. … The other reveals that the self-spreading of a lipid bilayer can be controlled by an electric field modulation between nanogap electrodes. …
NAID 130003370346