lipid-lowering drugs

出典: meddic

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出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2015/10/31 01:29:16」(JST)

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  • Statins and the brain: New perspective for old drugs.
  • Ling Q1, Tejada-Simon MV2.
  • Progress in neuro-psychopharmacology & biological psychiatry.Prog Neuropsychopharmacol Biol Psychiatry.2016 Apr 3;66:80-6. doi: 10.1016/j.pnpbp.2015.11.013. Epub 2015 Dec 2.
  • Statins are one of the most popular lipid-lowering drugs (LLDs). Upon oral administration, these drugs are well absorbed by the intestine and effectively used for the treatment of dyslipidemias. Recently, statins are becoming also well-known for their cholesterol-independent effects and their potent
  • PMID 26655447
  • Changes in lipoprotein lipase and endothelial lipase mass in familial hypercholesterolemia during three-drug lipid-lowering combination therapy.
  • Tada H1, Kobayashi J2, Kawashiri MA3, Miyashita K4, Nohara A5, Inazu A6, Nakajima K7, Mabuchi H5, Yamagishi M3.
  • Lipids in health and disease.Lipids Health Dis.2016 Apr 2;15(1):66.
  • BACKGROUND: This study was performed to compare the effects of three different lipid-lowering therapies (statins, ezetimibe, and colestimide) on lipoprotein lipase and endothelial lipase masses in pre-heparin plasma (pre-heparin LPL and EL mass, respectively) from patients with familial hypercholest
  • PMID 27039080
  • Alirocumab: A Review in Hypercholesterolemia.
  • Greig SL1, Deeks ED2.
  • American journal of cardiovascular drugs : drugs, devices, and other interventions.Am J Cardiovasc Drugs.2016 Apr;16(2):141-52. doi: 10.1007/s40256-016-0166-3.
  • Alirocumab (Praluent(®)) is a monoclonal antibody against proprotein convertase subtilisin/kexin type 9 (PCSK9) that is administered via subcutaneous injection every 2 weeks. Across ten phase III studies from the ODYSSEY clinical trial program in patients with heterozygous familial hypercholestero
  • PMID 26935836


  • Multidisciplinary Pharmacotherapeutic Options for Nonalcoholic Fatty Liver Disease
  • 中島 啓
  • International Journal of Hepatology 2012(Article ID 950693), 1-13, 2012
  • … In the last decade, it has been shown that metformin, thiazolidinediones, vitamin E, ezetimibe, n-3 polyunsaturated fatty acids, renin-angiotensin system (RAS) blockers, and antiobesity drugs may improve hepatic pathophysiological disorders as well as clinical parameters. … Accordingly, insulin sensitizers, antioxidative agents, Niemann-Pick C1-like 1 (NPC1L1) inhibitors, RAS blockers, and drugs that target the central nervous system may represent candidate pharmacotherapies for NAFLD and possibly NASH. …
  • NAID 120005352595
  • "Just Make It Lower" Is an Alternative Strategy of Lipid-Lowering Therapy With Statins in Japanese Patients – LDL-Cholesterol: The Lower, the Better; Is It True for Asians? (Con) –
  • Sakamoto Tomohiro,Ogawa Hisao,サカモト トモヒロ,オガワ ヒサオ,坂本 知浩,小川 久雄
  • Circulation journal : official journal of the Japanese Circulation Society 74(8), 1731-1741, 2010-07-25
  • … In this situation, not only strong but also standard statins are still advantageous and the so-called pleiotropic effects of the drugs come to the fore. …
  • NAID 10026566182


Although a change in life-style is often the method of first choice for lipid lowering, lipid-lowering drugs, in general, help to control elevated levels of different forms of lipids in patients with hyperlipidemia. While one group of drugs ...
Lipid-lowering drugs have had a profound effect on millions of Americans living with elevated cholesterol and triglyceride levels. Unfortunately, we are just beginning to learn how effective these drugs may be in HIV-positive people with high cholesterol or triglyceride levels. What's more, we're also ...






  • n.

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「(botany) either of the two parts of a bilabiate corolla or calyx」

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「either the outer margin or the inner margin of the aperture of a gastropod''s shell」

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「either of two fleshy folds of tissue that surround the mouth and play a role in speaking」

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「〈C〉『くちびる』,口もと / 《複数形で》(発音器官としての)くちびる,口 / 〈U〉《俗》生意気な言葉 / 〈C〉(容器などの)口,へり,縁;(峡谷・火山などの)口 / 〈C〉(植物の)唇弁(しんべん)」



  • n.

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「the act of causing something to move to a lower level」
letting down

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「the act of causing to become less」

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「(空模様が)険悪な,荒れ模様の / しかめっつらの,(顔つきが)不機嫌な」




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「use recreational drugs」
do drugs

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「administer a drug to; "They drugged the kidnapped tourist"」

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「a substance that is used as a medicine or narcotic」

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「『薬』,薬品,薬剤 / 『麻薬』,麻酔剤 / 〈人〉‘に'薬(特に麻酔剤)を与える / 〈飲食物〉‘に'(麻酔薬・毒薬などの)薬を混ぜる」


  [★] 脂質

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「an oily organic compound insoluble in water but soluble in organic solvents; essential structural component of living cells (along with proteins and carbohydrates)」
lipide, lipoid

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