出典: meddic


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出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2014/02/12 20:33:34」(JST)

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出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2015/12/14 02:16:25」(JST)

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  • Lentivirus‑mediated silencing of spindle and kinetochore‑associated protein 1 inhibits the proliferation and invasion of neuronal glioblastoma cells.
  • Shi X1, Chen X1, Peng H1, Song E2, Zhang T3, Zhang J4, Li J4, Swa H5, Li Y6, Kim S6, Liu X1, Zhang C1.
  • Molecular medicine reports.Mol Med Rep.2015 May;11(5):3533-8. doi: 10.3892/mmr.2015.3175. Epub 2015 Jan 9.
  • Spindle and kinetochore‑associated protein 1 (SKA1) is an important component of the human kinetochore, which plays a key role in mitosis. The resent study was designed to investigate the role of SKA1 in human glioblastoma. The results of the present study demonstrated that SKA1 was expressed in
  • PMID 25573192
  • Role of Ctf3 and COMA subcomplexes in meiosis: Implication in maintaining Cse4 at the centromere and numeric spindle poles.
  • Agarwal M1, Mehta G1, Ghosh SK2.
  • Biochimica et biophysica acta.Biochim Biophys Acta.2015 Mar;1854(3):671-84. doi: 10.1016/j.bbamcr.2014.12.032. Epub 2015 Jan 3.
  • During mitosis and meiosis, kinetochore, a conserved multi-protein complex, connects microtubule with the centromere and promotes segregation of the chromosomes. In budding yeast, central kinetochore complex named Ctf19 has been implicated in various functions and is believed to be made up of three
  • PMID 25562757
  • MAPping the Ndc80 loop in cancer: A possible link between Ndc80/Hec1 overproduction and cancer formation.
  • Tang NH1, Toda T.
  • BioEssays : news and reviews in molecular, cellular and developmental biology.Bioessays.2015 Mar;37(3):248-56. doi: 10.1002/bies.201400175. Epub 2015 Jan 2.
  • Mis-regulation (e.g. overproduction) of the human Ndc80/Hec1 outer kinetochore protein has been associated with aneuploidy and tumourigenesis, but the genetic basis and underlying mechanisms of this phenomenon remain poorly understood. Recent studies have identified the ubiquitous Ndc80 internal loo
  • PMID 25557589


  • Plk1 Phosphorylates CLIP-170 and Regulates Its Binding to Microtubules for Chromosome Alignment
  • , , , , , , , , , , ,
  • Cell Structure and Function 39(1), 45-59, 2014
  • … Furthermore, we demonstrate that during mitosis, stable kinetochore/MT attachment and subsequent chromosome alignment require CLIP-170 and a proper phosphorylation/dephosphorylation cycle at Ser312. …
  • NAID 130004053900
  • Dynamic regulation of kinetochore-microtubule interaction during mitosis
  • TANAKA Kozo
  • The journal of biochemistry 152(5), 415-424, 2012-11-01
  • NAID 10031166157
  • Dynamic regulation of kinetochore-microtubule interaction during mitosis
  • Tanaka Kozo
  • The journal of biochemistry 152(5), 415-424, 2012-11
  • NAID 40019507317







  • 中心体の、動原体の、中心粒の
central bodycentriolarcentriolecentrosomalcentrosomekinetochore

WordNet   license wordnet

「having or situated at or near a center」



  • 分裂期の染色体タンパク質複合体