intervertebral disc degeneration

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出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2014/04/15 21:23:14」(JST)

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  • Effect of disc degeneration on the muscle recruitment pattern in upright posture: a computational analysis.
  • Kim YE1, Choi HW.
  • Computer methods in biomechanics and biomedical engineering.Comput Methods Biomech Biomed Engin.2015 Nov;18(15):1622-31. doi: 10.1080/10255842.2014.936858. Epub 2014 Jul 15.
  • Based on the sensor driving control mechanism model, the effect of disc degeneration on the trunk muscle recruitment (TMR) pattern was analysed in erect standing posture. A previously developed computational model was used for this analysis, with modifications incorporating the T12-L1 motion segment
  • PMID 25025614
  • Efficacy of intervertebral disc regeneration with stem cells - A systematic review and meta-analysis of animal controlled trials.
  • Wang Z1, Perez-Terzic CM2, Smith J3, Mauck WD4, Shelerud RA5, Maus TP6, Yang TH7, Murad MH1, Gou S8, Terry MJ3, Dauffenbach JP3, Pingree MJ8, Eldrige JS4, Mohammed K1, Benkhadra K1, van Wijnen AJ9, Qu W10.
  • Gene.Gene.2015 Jun 10;564(1):1-8. doi: 10.1016/j.gene.2015.03.022. Epub 2015 Mar 19.
  • Management of intervertebral disc (IVD) degenerative disease is challenging, as it is accompanied by irreversible loss of IVD cells. Stem cell transplantation to the disc has shown promise in decelerating or arresting the degenerative process. Multiple pre-clinical animal trials have been conducted,
  • PMID 25796605
  • Matrix stiffness determines the fate of nucleus pulposus-derived stem cells.
  • Navaro Y1, Bleich-Kimelman N1, Hazanov L2, Mironi-Harpaz I2, Shachaf Y2, Garty S3, Smith Y4, Pelled G5, Gazit D5, Seliktar D2, Gazit Z6.
  • Biomaterials.Biomaterials.2015 May;49:68-76. doi: 10.1016/j.biomaterials.2015.01.021. Epub 2015 Feb 14.
  • Intervertebral disc (IVD) degeneration and consequent low-back pain present a major medical challenge. Nucleus pulposus-derived stem cells (NP-SCs) may lead to a novel therapy for this severe disease. It was recently shown that survival and function of mature NP cells are regulated in part by tissue
  • PMID 25725556


  • L4/5単椎間固定術における隣接椎間変化の検討 : 術前MRI画像による椎間板変性およびModic変化との関連 (日本脊椎インストゥルメンテーション学会 特集号)
  • 鳥越 一郎,江幡 重人,佐藤 浩一 [他]
  • Journal of spine research : official journal of the Japanese Society for Spine Surgery and Related Research 3(10), 1335-1338, 2012-10
  • NAID 40019475289
  • 脊椎椎間板の力学的特性 : 動的負荷培養装置を用いた機械受容体の検討 (特集 骨・関節のバイオメカニクス : 最近の進歩)
  • 蔵川 拓外,角谷 賢一朗,森田 有亮 [他]
  • 整形・災害外科 55(11), 1341-1346, 2012-10
  • NAID 40019462144


There is frequently cleft formation with fissures forming within the disc, particularly in the nucleus. Nerves and blood vessels are increasingly found with degeneration [15]. Cell proliferation occurs, leading to cluster ...
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intervertebral disc degeneration



  • n.
degeneracydegeneratedegenerativedenaturationdenatureinvolutionretractretrograde degenerationretrograde degradationunfolding

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「the process of declining from a higher to a lower level of effective power or vitality or essential quality」

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「passing from a more complex to a simpler biological form」

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  • n.

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「=record / =disk」



  • 椎間の

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「pertaining to the space between two vertebrae」



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