イノシトール一リン酸、イノシトール1リン酸、イノシトールリン酸
- 関
- inositol phosphate、IP
WordNet
- an optically inactive alcohol that is a component of the vitamin B complex
PrepTutorEJDIC
- (野球で)innings pitched
Wikipedia preview
出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2013/08/13 11:38:28」(JST)
[Wiki en表示]
Inositol phosphates are a group of mono- to polyphosphorylated inositols. They play crucial roles in diverse cellular functions, such as cell growth, apoptosis, cell migration, endocytosis, and cell differentiation. The group comprises:
- inositol monophosphate (IP)
- inositol bisphosphate (IP2)
- inositol trisphosphate (IP3)
- inositol pentakisphosphate (IP5)
- inositol hexaphosphate (IP6) also known as phytic acid, or phytate (as a salt).
Contents
- 1 Functions
- 1.1 Inositol triphosphate
- 1.2 Other
- 2 References
- 3 External links
Functions[edit source | edit]
Inositol triphosphate[edit source | edit]
Main article: Inositol triphosphate
Inositol trisphosphates act on the inositol triphosphate receptor to release calcium into the cytoplasm. Further reading: Function of calcium in humans
Other[edit source | edit]
Inositol tetra-, penta-, and hexa-phosphates have been implicated in gene expression[1] and Steger[2] (both in Science Magazine).
References[edit source | edit]
- ^ Shen, X; Xiao, H; Ranallo, R; Wu, WH; Wu, C (2003). "Modulation of ATP-dependent chromatin-remodeling complexes by inositol polyphosphates". Science 299 (5603): 112–4. doi:10.1126/science.1078068. PMID 12434013.
- ^ Steger, DJ; Haswell, ES; Miller, AL; Wente, SR; O'Shea, EK (2003). "Regulation of chromatin remodeling by inositol polyphosphates". Science 299 (5603): 114–6. doi:10.1126/science.1078062. PMC 1458531. PMID 12434012.
External links[edit source | edit]
- An Image of Inositol
- Inositol Phosphates at the US National Library of Medicine Medical Subject Headings (MeSH)
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Lipids: phospholipids
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Glycerol backbone
(Glycerophospholipids/
Phosphoglycerides) |
Phosphatidyl-: -ethanolamine/cephalin (PE) · -choline/lechithin (PC) · -serine (PS) · -glycerol (PG) · -inositol (PI) (glyco- (GPI))
Phosphoinositides: PIP (PI(3)P, PI(4)P, PI(5)P) · PIP2 (PI(3,4)P2, PI(3,5)P2, PI(4,5)P2) · PIP3
Cardiolipin
Ether lipids: Plasmalogen (Platelet-activating factor)
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| Sphingosine backbone |
Sphingomyelin
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| Metabolites |
Inositol phosphate · Inositol
Lysophosphatidic acid
Choline · Phosphocholine · Citicoline
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mt, k, c/g/r/p/y/i, f/h/s/l/o/e, a/u, n, m
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k, cgrp/y/i, f/h/s/l/o/e, au, n, m, epon
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m (A16/C10), i (k, c/g/r/p/y/i, f/h/s/o/e, a/u, n, m)
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- biochemical families: carbohydrates
- alcohols
- glycoproteins
- glycosides
- lipids
- eicosanoids
- fatty acids / intermediates
- phospholipids
- sphingolipids
- steroids
- nucleic acids
- constituents / intermediates
- proteins
- Amino acids / intermediates
- tetrapyrroles / intermediates
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UpToDate Contents
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English Journal
- Structural and functional characterization of the kindlin-1 pleckstrin homology domain.
- Yates LA, Lumb CN, Brahme NN, Zalyte R, Bird LE, De Colibus L, Owens RJ, Calderwood DA, Sansom MS, Gilbert RJ.SourceFrom the Division of Structural Biology, Wellcome Trust Centre for Human Genetics, University of Oxford, Roosevelt Drive, Oxford OX3 7BN, United Kingdom.
- The Journal of biological chemistry.J Biol Chem.2012 Dec 21;287(52):43246-61. doi: 10.1074/jbc.M112.422089. Epub 2012 Nov 6.
- Inside-out activation of integrins is mediated via the binding of talin and kindlin to integrin β-subunit cytoplasmic tails. The kindlin FERM domain is interrupted by a pleckstrin homology (PH) domain within its F2 subdomain. Here, we present data confirming the importance of the kindlin-1 PH domai
- PMID 23132860
- Changes in taste receptor cell [Ca2+]i modulate chorda tympani responses to bitter, sweet, and umami taste stimuli.
- Desimone JA, Phan TH, Ren Z, Mummalaneni S, Lyall V.SourceVirginia Commonwealth Univ., Molecular Medical Research Bldg. (MMRB#5052, 1220 East Broad St., Richmond, VA 23219. vlyall@vcu.edu).
- Journal of neurophysiology.J Neurophysiol.2012 Dec;108(12):3221-32. doi: 10.1152/jn.00129.2012. Epub 2012 Sep 19.
- The relationship between taste receptor cell (TRC) intracellular Ca(2+) ([Ca(2+)](i)) and rat chorda tympani (CT) nerve responses to bitter (quinine and denatonium), sweet (sucrose, glycine, and erythritol), and umami [monosodium glutamate (MSG) and MSG + inosine 5'-monophosphate (IMP)] taste stimul
- PMID 22993258
- Mechanism of sperm capacitation and the acrosome reaction: role of protein kinases.
- Ickowicz D, Finkelstein M, Breitbart H.SourceThe Mina & Everard Faculty of Life Sciences, Bar-Ilan University, Ramat-Gan 52100, Israel.
- Asian journal of andrology.Asian J Androl.2012 Nov;14(6):816-21. doi: 10.1038/aja.2012.81. Epub 2012 Sep 24.
- Mammalian sperm must undergo a series of biochemical and physiological modifications, collectively called capacitation, in the female reproductive tract prior to the acrosome reaction (AR). The mechanisms of these modifications are not well characterized though protein kinases were shown to be invol
- PMID 23001443
Japanese Journal
- Antiplatelet Effects of Caffeic Acid Due to Ca2＋ MobilizationInhibition Via cAMP-Dependent Inositol-1, 4, 5-Trisphosphate Receptor Phosphorylation
- , , , , ,
- Journal of Atherosclerosis and Thrombosis 21(1), 23-37, 2014
- … In this study, we investigated the effects of caffeic acid (CAFA), a phenolic acid, on Ca2＋-antagonistic cyclic nucleotides associated with the phosphorylation of inositol 1,4,5-trisphosphate receptor (IP3R) and vasodilator-stimulated phosphoprotein (VASP) and the thromboxane A2 (TXA2)-associated microsomal cyclooxygenase-1 (COX-1) activity in collagen (10 μg/mL)-stimulated platelet aggregation.Methods: Washed platelets (108/mL) obtained from Sprague-Dawley rats (6-7 weeks old, male) were preincubated for 3 minutes at 37℃ in the presence of 2 mM …
- NAID 130004845457
- Effects of amitriptyline, a tricyclic antidepressant, on smooth muscle reactivity in isolated rat trachea
- MATSUNAGA SHOJI,SHIBATA OSAMU,NISHIOKA KENJI,TSUDA ATSUSHI,MAKITA TETSUJI,SUMIKAWA KOJI
- Journal of anesthesia 23(3), 385-391, 2009-08-20
- … In addition, inositol monophosphate (IP1) accumulation was measured to examine its effects on inositol 1, 4, 5-trisphosphate (IP(3)) production during stimulation with ACh. …
- NAID 10027264183
- Hyperosmolarity Attenuates the Contraction of Rat Trachea Through the Inhibition of Phosphatidylinositol Response
- Saito Masataka. et. al.
- Acta medica Nagasakiensia 52(4), 107-110, 2008-03
- … In vitro measurements of isometric tension and [3H] inositol monophosphate (IP1) formed were conducted by using rat tracheal rings and slices. …
- NAID 110006617688
Related Links
- Supplement information for Inositol Monophosphate including symptoms, diseases, prevention, complications, and deficiencies. ... Inositol Monophosphate Inositol Monophosphate: Inositol monophosphate is a form of inositol that is ...
- Structure, properties, spectra, suppliers and links for: INOSITOL MONOPHOSPHATE. ... Predicted data is generated using the US Environmental Protection Agency’s EPISuite , for more information see their website. Log Octanol ...
★リンクテーブル★
[★]
- 英
- inositol monophosphate, IMP
- 同
- イノシトールリン酸, イノシトール1リン酸
IMPの生合成
[★]
- 英
- inositol phosphate, IP
- 関
- inositol monophosphate
[★]
- 英
- inositol monophosphate
- 関
- イノシトール一リン酸、イノシトールリン酸
[★]
[★]
イノシトール
- 関
- myoinositol