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「a protease inhibitor (trade name Crixivan) used for treating HIV」

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出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2015/08/28 13:54:46」(JST)

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  • Liquid chromatography tandem mass spectrometric studies of indinavir sulphate and its forced degradation products.
  • Rao RN, Vali RM, Raju SS.SourceAnalytical Chemistry Division, Discovery Laboratory, Indian Institute of Chemical Technology, Tarnaka, Hyderabad 500 607, India.
  • Journal of pharmaceutical and biomedical analysis.J Pharm Biomed Anal.2013 Feb 23;74:101-10. doi: 10.1016/j.jpba.2012.10.025. Epub 2012 Oct 29.
  • Indinavir sulphate was subjected to forced degradation under hydrolysis (acidic, basic and neutral), oxidation, photolysis and thermal stress as prescribed by ICH guidelines. It was degraded under acidic, basic, neutral and oxidative stress conditions, while it was stable under other conditions. Aft
  • PMID 23245240
  • Exploring food effects on indinavir absorption with human intestinal fluids in the mouse intestine.
  • Holmstock N, Bruyn TD, Bevernage J, Annaert P, Mols R, Tack J, Augustijns P.SourceLaboratory for Pharmacotechnology and Biopharmacy, KU Leuven, Campus Gasthuisberg, O&N 2, Herestraat 49, Box 921, B-3000 Leuven, Belgium. Electronic address:
  • European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.Eur J Pharm Sci.2013 Feb 9. pii: S0928-0987(13)00053-5. doi: 10.1016/j.ejps.2013.01.012. [Epub ahead of print]
  • Food can have a significant impact on the pharmacokinetics of orally administered drugs, as it may affect drug solubility as well as permeability. Since fed state conditions cannot easily be implemented in the presently available permeability tools, including the frequently used Caco-2 system, explo
  • PMID 23402972
  • Indinavir and nelfinavir inhibit proximal insulin receptor signalling and salicylate abrogates inhibition: Potential role of the NFkappa B pathway.
  • Ismail WI, King JA, Anwar K, Pillay TS.SourceDivision of Chemical Pathology, University of Cape Town, Cape Town 7925, South Africa; Division of Pharmaceutical Biotechnology, Faculty of Pharmacy, Universiti Teknologi MARA, Puncak Alam Campus, 42300 Bandar Puncak Alam, Selangor, Malaysia.
  • Journal of cellular biochemistry.J Cell Biochem.2013 Feb 5. doi: 10.1002/jcb.24513. [Epub ahead of print]
  • The molecular basis of insulin resistance induced by HIV protease inhibitors (HPIs) remains unclear. In this study, Chinese hamster ovary cells transfected with high levels of human insulin receptor (CHO-IR) and 3T3-L1 adipocytes were used to elucidate the mechanism of this side effect. Indinavir an
  • PMID 23386514


  • CH05-10, a novel indinavir analog, is a broad-spectrum antitumor agent that induces cell cycle arrest, apoptosis, endoplasmic reticulum stress and autophagy
  • YOU Jianlan,HE Zhengxiang,CHEN Lili,DENG Gang,LIU Wei,QIN Li,QIU Fayang,CHEN Xiaoping
  • Cancer science 101(12), 2644-2651, 2010-12-10
  • NAID 10027834910
  • 末期腎不全に至ったHIV患者10症例の臨床的検討
  • 関谷 紀貴,中村 裕也,柳澤 如樹 [他],菅沼 明彦,今村 顕史,味澤 篤,安藤 稔
  • 日本透析医学会雑誌 = Journal of Japanese Society for Dialysis Therapy 43(7), 581-586, 2010-07-28
  • … ら7例(70%),高血圧は3例(30%)から9例(90%),高脂血症は1例(10%)から6例(60%)に増加した.腎毒性を有する抗レトロウイルス薬の代表であるTenofovir disoproxil fumarate(TDF)の内服歴は1例もなく,Indinavir(IDV)の内服歴は2例にあった.その他の腎毒性のある薬剤では,trimethoprim-sulfamethoxazole(ST)合剤の内服歴が4例,nonsteroidal anti-inflammatory drugs(NSAIDs)の内服歴が3例にあった.ESRDに至ったHIV感染者10例は,HAA …
  • NAID 10026547437
  • A liquid chromatography-tandem mass spectrometry assay for quantification of nevirapine, indinavir, atazanavir, amprenavir, saquinavir, ritonavir, lopinavir, efavirenz, tipranavir, darunavir and maraviroc in the plasma of patients infected with HIV
  • Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 877(27), 3072-3082, 2009-10-01
  • NAID 10028025117


Clinical and research information on drug-induced liver injury. ... Comment An example of possible acute idiosyncratic hepatocellular injury with onset after 7 weeks of starting indinavir, a severe course and protracted ...
抗エイズ抗感染薬のクリクシバン抗エイズ薬の個人輸入のサイトです。海外医薬品の個人輸入 クリクシバン成分インディナビル(Indinavir) 海外医薬品をご提供しております。


Indinavir - Wikipedia, the free Crixivan (indinavir) Drug Side Effects Indinavir Sulfate - patient information Indinavir :: General Health :: Generics Web information on IndinavirFile:Indinavir.jpg - Wikimedia Commons

拡張検索indinavir sulfate ethonolate



acute tubulointerstitial nephritis
急性間質性腎炎 acute interstitial nephritis, AIN


  • 薬剤性
  • 感染症
  • 特発性



indinavir, IDV

indinavir sulfate ethonolate」