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Wilson C, Contreras-Ferrat A, Venegas N, Osorio-Fuentealba C, Pávez M, Montoya K, Durán J, Maass R, Lavandero S, Estrada M.SourcePrograma de Fisiología y Biofísica y Programa de Biología Celular y Molecular, Facultad de Medicina, Instituto de Ciencias Biomédicas, Universidad de Chile, Santiago, Chile.
Journal of cellular physiology.J Cell Physiol.2013 Dec;228(12):2399-407. doi: 10.1002/jcp.24413.
Testosterone exerts important effects in the heart. Cardiomyocytes are target cells for androgens, and testosterone induces rapid effects via Ca(2+) release and protein kinase activation and long-term effects via cardiomyocyte differentiation and hypertrophy. Furthermore, it stimulates metabolic eff
PMID 23757167

Validation of a fast method for quantitative analysis of elvitegravir, raltegravir, maraviroc, etravirine, tenofovir, boceprevir and 10 other antiretroviral agents in human plasma samples with a new UPLC-MS/MS technology.

Djerada Z, Feliu C, Tournois C, Vautier D, Binet L, Robinet A, Marty H, Gozalo C, Lamiable D, Millart H.SourceDepartment of Pharmacology, E.A.3801, SFR CAP-santé, Reims University Hospital, 51, rue Cognacq-Jay, 51095 Reims Cedex, France. Electronic address: zoubir.djerada@univ-reims.fr.
Journal of pharmaceutical and biomedical analysis.J Pharm Biomed Anal.2013 Dec;86:100-11. doi: 10.1016/j.jpba.2013.08.002. Epub 2013 Aug 12.
Therapeutic drug monitoring (TDM) of antiretrovirals requires accurate and precise analysis of plasma drug concentrations. This work describes a simple, fast and sensitive UPLC-MS/MS method for determination of the commonly used protease inhibitors such as amprenavir, atazanavir, darunavir, indinavi
PMID 23995753

Simplifying antiretroviral therapy to lopinavir/ritonavir monotherapy did not improve quality of life and therapy adherence in pre-treated HIV-infected children.

Bunupuradah T, Panthong A, Kosalaraksa P, Wongsabut J, Puthanakit T, Lumbiganon P, Chuanjaroen T, Sopharak C, Udompanit T, Prasitsuebsai W, Pancharoen C, Ananworanich J.SourceHIV-NAT, Thai Red Cross Research Center, 104 Ratchadamri Rd., Pathuwam, , Bangkok, Thailand, 10330, 662-652-3040, 662-252-5779 ; torsak.b@hivnat.org.
AIDS research and human retroviruses.AIDS Res Hum Retroviruses.2013 Nov 25. [Epub ahead of print]
We reported quality of life (QOL) and adherence in HIV-infected children after simplifying antiretroviral regimen by switching to lopinavir/ritonavir monotherapy (mLPV/r). HIV-infected children with HIV-RNA <50copies/ml while using second-line double boosted protease inhibitors were switched to m
PMID 24274723