- 関
- thrombogenesis、thrombogenicity、thrombus formation
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出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2013/06/29 16:42:02」(JST)
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Thrombogenicity refers to the tendency of a material in contact with the blood to produce a thrombus, or clot. It not only refers to fixed thrombi but also to emboli, thrombi which have become detached and travel through the bloodstream. Thrombogenicity can also encompass events such as the activation of immune pathways and the complement system. All materials are considered to be thrombogenic[citation needed] with the exception of the normal state of endothelial cells which line blood vessels.[1] Certain medical implants appear non-thrombogenic due to high flow rates of blood past the implant, but in reality all are thrombogenic to a degree. Various surface treatments are available to minimize these thrombogenic effects.
A thrombogenic implant will eventually be covered by a fibrous capsule, the thickness of this capsule can be considered one measure of thrombogenicity, and if extreme can lead to the failure of the implant.
See also[edit]
References[edit]
- ^ López JA, Chen J (2009). "Pathophysiology of venous thrombosis". Thromb Res 123 (Suppl 4): S30–4. doi:10.1016/S0049-3848(09)70140-9. PMID 19303501.
Further reading[edit]
- Paul, R; Marseille, O; Hintze, E; Huber, L; Schima, H; Reul, H; Rau, G (1998). "In vitro thrombogenicity testing of artificial organs". The International journal of artificial organs 21 (9): 548–52. PMID 9828061.
- Kenny, DA; Berger, K; Walker, MW; Robel, SB; Boguslavsky, L; Ray, LI; Lischko, MM; Sauvage, LR (1980). "Experimental comparison of the thrombogenicity of fibrin and PTFE flow surfaces.". Annals of surgery 191 (3): 355–61. PMC 1344708. PMID 6444800.
UpToDate Contents
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English Journal
- Inherited antithrombin deficiency and anabolic steroids: a risky combination.
- Choe H1, Elfil M, DeSancho MT.
- Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis.Blood Coagul Fibrinolysis.2016 Sep;27(6):717-9. doi: 10.1097/MBC.0000000000000454.
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- PMID 26588446
- Silk fibroin as a non-thrombogenic biomaterial.
- Adalı T1, Uncu M2.
- International journal of biological macromolecules.Int J Biol Macromol.2016 Sep;90:11-9. doi: 10.1016/j.ijbiomac.2016.01.088. Epub 2016 Jan 27.
- Silk fibroin (SF), is a very attractive protein-polymer, being processed into a variety of formats to match structural and morphological features for specific biomedical applications. The aim of the present work is to investigate blood compatibility of two forms, films and scaffolds, of silk fibroin
- PMID 26826290
- Sensory quality and chemical composition of meat from lambs fed diets enriched with fish and rapeseed oils, carnosic acid and seleno-compounds.
- Jaworska D1, Czauderna M2, Przybylski W3, Rozbicka-Wieczorek AJ2.
- Meat science.Meat Sci.2016 Sep;119:185-92. doi: 10.1016/j.meatsci.2016.05.003. Epub 2016 May 6.
- The aim of the study was to evaluate longissimus muscle quality in lambs fed diets including fish oil (FO), rapeseed oil (RO), carnosic acid (CA) and seleno-compounds. Lambs were fed one of diets: Group I - the basal diet (BD) with 3% RO; Group II - BD with 2% RO and 1% FO; Group III - BD with 2% RO
- PMID 27214277
Japanese Journal
- 2E33 マイクロ流路を用いた血流の衝突と血栓形成因子の活性化に関する研究
- 1A22 光干渉断層装置を用いたリアルタイム観察による流れ場が血栓形成に与える影響の検討
- G0400303 パルスプラズマCVD法により作製したa-BC:H膜の血液適合性
- 年次大会 : Mechanical Engineering Congress, Japan 2015, "G0400303-1"-"G0400303-5", 2015-09-13
- NAID 110010048299
Related Links
- Thrombogenicity refers to the tendency of a material in contact with the blood to produce a thrombus, or clot. It not only refers to fixed thrombi but also to emboli, thrombi which have become detached and travel through the bloodstream.
- 0.01 sec. throm·bo·gen·ic (thr m b -j n k). adj. Causing or resulting in thrombosis or coagulation of the blood. thrombogenic. [-jen′ik]. Etymology: Gk, thrombos + genein, to produce. pertaining to a thrombus or a factor that causes a thrombus.
★リンクテーブル★
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- 英
- thrombus formation、thrombogenesis、thrombogenic
- 関
- 血栓形成性
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- 英
- thrombogenicity、thrombogenic
- 関
- 血栓形成
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- 関
- thrombogenic