WordNet
- work natural fibers into a thread; "spin silk"
- prolong or extend; "spin out a visit" (同)spin out
- the act of rotating rapidly; "he gave the crank a spin"; "it broke off after much twisting" (同)twirl, twist, twisting, whirl
- a distinctive interpretation (especially as used by politicians to sway public opinion); "the campaign put a favorable spin on the story"
- a short drive in a car; "he took the new car for a spin"
- a swift whirling motion (usually of a missile)
- revolve quickly and repeatedly around ones own axis; "The dervishes whirl around and around without getting dizzy" (同)spin around, whirl, reel, gyrate
- form a web by making a thread; "spiders spin a fine web"
- make up a story; "spin a yarn"
- stream in jets, of liquids; "The creek spun its course through the woods"
- twist and turn so as to give an intended interpretation; "The Presidents spokesmen had to spin the story to make it less embarrassing"
- a part of the cell containing DNA and RNA and responsible for growth and reproduction (同)cell_nucleus, karyon
- (astronomy) the center of the head of a comet; consists of small solid particles of ice and frozen gas that vaporizes on approaching the sun to form the coma and tail
- any histologically identifiable mass of neural cell bodies in the brain or spinal cord
- the positively charged dense center of an atom
- of or relating to the spine or spinal cord; "spinal cord"; "spinal injury"
- the main sensory nerve of the face and motor nerve for the muscles of mastication (同)trigeminal_nerve, trigeminus, nervus_trigeminus, fifth_cranial_nerve
PrepTutorEJDIC
- (羊毛などから)〈糸など〉‘を'『紡ぐ』《+『名』+『out of』+『名』〈羊毛〉》,(糸などに)〈羊毛など〉‘を'紡ぐ《+『名』〈羊毛〉+『into』+『名』》 / 〈クモ・カイコなどが〉〈糸〉‘を'『吐く』;〈巣・繭〉‘を'かける / …‘を'くるくる回す / 〈物語など〉‘を'作る,話す / 『糸を紡ぐ』;〈クモ・カイコなどが〉糸を吐く / 〈こまなどが〉くるくる回る / 〈車などが〉疾走する / 〈頭などが〉くらくらする / 〈C〉〈U〉くるくる回すこと;回転 / 〈C〉《単数形で》(車などの)一走り / 〈C〉(飛行機の)きりもみ降下 / 〈C〉《単数形で》(価値などの)急落
- 中心,核 / (生物の)細胞核 / 原子核
- 背骨の / せき髄麻酔
Wikipedia preview
出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2014/05/31 08:10:21」(JST)
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- 1. 三叉神経痛 trigeminal neuralgia
- 2. 頭蓋顔面痛の概要 overview of craniofacial pain
- 3. 成人における脊髄損傷：定義、機序、および放射線学的所見 spinal column injuries in adults definitions mechanisms and radiographs
- 4. 脊髄に影響を与える疾患 disorders affecting the spinal cord
- 5. 脊髄性筋萎縮症 spinal muscular atrophy
English Journal
- The normal and variant clinical anatomy of the sensory supply of the orbit.
- Voirol JR1, Vilensky JA.Author information 1Department of Anatomy and Cell Biology, Indiana University School of Medicine, Fort Wayne, IN.AbstractOrbital and retro-orbital pain are relatively common clinical conditions that are associated with such disorders as trigeminal, lacrimal, and ciliary neuralgia, cluster headaches, paroxysmal hemicrania, inflammatory orbital pseudotumor, trochleitis, and herpetic neuralgia ophthalmicus, thus making the nerves supplying the orbit of great clinical importance. Surprisingly, how pain from this region reaches conscious levels is enigmatic. Classically, it has been assumed that pain reaches the ophthalmic division of the trigeminal nerve (V1 ) and travels to the descending spinal trigeminal nucleus. However, exactly where the receptors for orbital pain are located and how impulses reach V1 is speculative. In this project, we reviewed all of the reported connections between the orbital nerves and V1 in order to understand how pain from this region is transmitted to the brain. We found reported neural connections to exist between cranial nerve (CN) V1 and CNs III, IV, and VI within the orbit, as well as direct neural branches to extra-ocular muscles from the nasociliary, frontal, and supraorbital nerves. We also found reported neural connections to exist between the presumed carotid plexus and CN VI and CN V1 , CN VI and CN V1 and V2 , and between CN V1 and CN III, all within the cavernous sinus. Whether or not these connections are sympathetic or sensory or some combination of both connections remains unclear. An understanding of the variability and frequency of these neural connections could lead to safer surgical procedures of the orbit and effective treatments for patients with orbital pain. Clin. Anat. 27:169-175, 2014. © 2014 Wiley Periodicals, Inc.
- Clinical anatomy (New York, N.Y.).Clin Anat.2014 Mar;27(2):169-75. doi: 10.1002/ca.22328. Epub 2014 Jan 16.
- Orbital and retro-orbital pain are relatively common clinical conditions that are associated with such disorders as trigeminal, lacrimal, and ciliary neuralgia, cluster headaches, paroxysmal hemicrania, inflammatory orbital pseudotumor, trochleitis, and herpetic neuralgia ophthalmicus, thus making t
- PMID 24430947
- Differential brain activity in subjects with painful trigeminal neuropathy and painful temporomandibular disorder.
- Youssef AM1, Gustin SM1, Nash PG1, Reeves JM1, Petersen ET2, Peck CC3, Murray GM3, Henderson LA4.Author information 1Department of Anatomy and Histology, University of Sydney, Sydney, NSW 2006, Australia.2Departments of Radiology and Radiotherapy, University Medical Center Utrecht, The Netherlands.3Jaw Function and Orofacial Pain Research Unit, Faculty of Dentistry, University of Sydney, Westmead Hospital, Westmead, NSW 2006, Australia.4Department of Anatomy and Histology, University of Sydney, Sydney, NSW 2006, Australia. Electronic address: lukeh@anatomy.usyd.edu.au.AbstractHuman brain imaging investigations have revealed that acute pain is associated with coactivation of numerous brain regions, including the thalamus, somatosensory, insular, and cingulate cortices. Surprisingly, a similar set of brain structures is not activated in all chronic pain conditions, particularly chronic neuropathic pain, which is associated with almost exclusively decreased thalamic activity. These inconsistencies may reflect technical issues or fundamental differences in the processing of acute compared with chronic pain. The appreciation of any differences is important because better treatment development will depend on understanding the underlying mechanisms of different forms of pain. In this investigation, we used quantitative arterial spin labeling to compare and contrast regional cerebral blood flow (CBF) patterns in individuals with chronic neuropathic orofacial pain (painful trigeminal neuropathy) and chronic nonneuropathic orofacial pain (painful temporomandibular disorder). Neuropathic pain was associated with CBF decreases in a number of regions, including the thalamus and primary somatosensory and cerebellar cortices. In contrast, chronic nonneuropathic pain was associated with significant CBF increases in regions commonly associated with higher-order cognitive and emotional functions, such as the anterior cingulate and dorsolateral prefrontal cortices and the precuneus. Furthermore, in subjects with nonneuropathic pain, blood flow increased in motor-related regions as well as within the spinal trigeminal nucleus.
- Pain.Pain.2014 Mar;155(3):467-75. doi: 10.1016/j.pain.2013.11.008. Epub 2013 Nov 21.
- Human brain imaging investigations have revealed that acute pain is associated with coactivation of numerous brain regions, including the thalamus, somatosensory, insular, and cingulate cortices. Surprisingly, a similar set of brain structures is not activated in all chronic pain conditions, particu
- PMID 24269492
- Central Terminal Sensitization of TRPV1 by Descending Serotonergic Facilitation Modulates Chronic Pain.
- Kim YS1, Chu Y2, Han L1, Li M3, Li Z1, Lavinka PC1, Sun S1, Tang Z4, Park K1, Caterina MJ5, Ren K2, Dubner R2, Wei F6, Dong X7.Author information 1Department of Neuroscience, Center of Sensory Biology, the Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.2Department of Neural and Pain Sciences, Program in Neuroscience, Dental School, University of Maryland, Baltimore, MD 21201, USA.3Department of Neural and Pain Sciences, Program in Neuroscience, Dental School, University of Maryland, Baltimore, MD 21201, USA; Department of Anesthesiology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China.4Nanjing University of Chinese Medicine, Nanjing 210046, China.5Department of Neuroscience, Center of Sensory Biology, the Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA; Department of Biological Chemistry, the Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.6Department of Neural and Pain Sciences, Program in Neuroscience, Dental School, University of Maryland, Baltimore, MD 21201, USA. Electronic address: fwei@umaryland.edu.7Department of Neuroscience, Center of Sensory Biology, the Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA; Howard Hughes Medical Institute, the Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA. Electronic address: xdong2@jhmi.edu.AbstractThe peripheral terminals of primary nociceptive neurons play an essential role in pain detection mediated by membrane receptors like TRPV1, a molecular sensor of heat and capsaicin. However, the contribution of central terminal TRPV1 in the dorsal horn to chronic pain has not been investigated directly. Combining primary sensory neuron-specific GCaMP3 imaging with a trigeminal neuropathic pain model, we detected robust neuronal hyperactivity in injured and uninjured nerves in the skin, soma in trigeminal ganglion, and central terminals in the spinal trigeminal nucleus. Extensive TRPV1 hyperactivity was observed in central terminals innervating all dorsal horn laminae. The central terminal TRPV1 sensitization was maintained by descending serotonergic (5-HT) input from the brainstem. Central blockade of TRPV1 or 5-HT/5-HT3A receptors attenuated central terminal sensitization, excitatory primary afferent inputs, and mechanical hyperalgesia in the territories of injured and uninjured nerves. Our results reveal central mechanisms facilitating central terminal sensitization underlying chronic pain.
- Neuron.Neuron.2014 Feb 19;81(4):873-87. doi: 10.1016/j.neuron.2013.12.011. Epub 2014 Jan 23.
- The peripheral terminals of primary nociceptive neurons play an essential role in pain detection mediated by membrane receptors like TRPV1, a molecular sensor of heat and capsaicin. However, the contribution of central terminal TRPV1 in the dorsal horn to chronic pain has not been investigated dir
- PMID 24462040
Japanese Journal
- Immunohistochemical Mapping of TRK-Fused Gene Products in the Rat Brainstem
- Takeuchi Shigeko,Masuda Chiaki,Maebayashi Hisae,Tooyama Ikuo
- ACTA HISTOCHEMICA ET CYTOCHEMICA 45(1), 57-64, 2012
- … In the present study, we mapped the TFG-positive neurons in the brainstem, cerebellum, and spinal cord of rats. … In the brainstem, neurons intensely positive for TFG were distributed in the raphe nuclei, the gigantocellular reticular nucleus, the reticulotegmental nucleus of the pons, and some cranial nerve nuclei such as the trigeminal nuclei, the vestibulocochlear nuclei, and the dorsal motor nucleus of the vagus. …
- NAID 130001854315
- Peripheral and Central Mechanisms of Trigeminal Neuropathic and Inflammatory Pain
- TAKEDA Mamoru,MATSUMOTO Shigeji,SESSLE Barry J.,SHINODA Masamichi,IWATA Koichi
- Journal of oral biosciences 53(4), 318-329, 2011-11-20
- NAID 10030175500
- Neuropeptide Effects in the Trigeminal System : Pathophysiology and Clinical Relevance in Migraine
- MESSLINGER Karl,FISCHER Michael J. M.,LENNERZ Jochen K.
- Keio journal of medicine 60(3), 82-89, 2011-09-01
- … Substance P and CGRP are produced from a subset of trigeminal afferents, whereas VIP derives from parasympathetic efferents. … The activity of spinal trigeminal neurons is a sensitive integrative measure of trigeminal activity and is partly under the control of CGRP, most likely via central mechanisms. …
- NAID 10029624739
Related Links
- The spinal trigeminal nucleus is a nucleus in the medulla that receives information about deep/crude touch, pain, and temperature from the ipsilateral face. The facial (cranial nerve 7), glossopharyngeal (CN9), and vagus nerves ( CN10) also ...
Related Pictures
★リンクテーブル★
| リンク元 | 「三叉神経脊髄路核」「spinal trigeminal nuclei」「三叉脊髄核」「nucleus tractus spinalis nervi trigemini」 |
| 関連記事 | 「spinal」「trigeminal」「spin」「trigeminal nucleus」 |
「三叉神経脊髄路核」
- 英
- spinal trigeminal nucleus (KL), nucleus of spinal tract of trigeminal nerve
- ラ
- nucleus tractus spinalis nervi trigemini
- 関
- 三叉神経脊髄路、三叉神経主知覚核、三叉神経中脳路核、三叉神経
- 図：NCUR.136,138,176,179
- 橋-延髄、あるいは橋の下部から第3頚髄(CNUR.176)にかけて下方に長く伸びている。
- 脊髄後角に相当し、特に尾側亜核は脊髄後角と相同な層構造を持ち、触、温・痛覚を伝える。(SP.232)
- 三叉神経支配領域やその周辺領域から発せられる侵害感覚、温度感覚の各情報を広く受け入れている(CNUR.176)。
- 延髄レベルでは後外側に位置している。
- 内側毛帯で交叉(2007年度後期生理学授業プリント 図：CNUR.179)
臨床関連
- ワレンベルグ症候群(延髄外束晶行軍)：脳神経は中脳レベルであるが、神経核は延髄にまで及ぶので、顔面の感覚が障害を受ける。
「spinal trigeminal nuclei」
「三叉脊髄核」
「nucleus tractus spinalis nervi trigemini」
「spinal」
- adj.
- 脊髄の、脊髄性の、脊柱の
「trigeminal」
- adj.
- 三叉神経の
「spin」