WordNet
- (medicine) any disturbance in the functioning of an organ or body part or a disturbance in the functioning of a social group; "erectile dysfunction"; "sexual relationship dysfunction" (同)disfunction
- constituting a tube; having hollow tubes (as for the passage of fluids) (同)cannular, tubelike, tube-shaped, vasiform
- situated nearest to point of attachment or origin; "the proximal end of a bone"
PrepTutorEJDIC
- 機能障害,機能不全
- 管状の,管から成る
- (骨などが)近位の(体の中心に近いこと)
- 腎臓の
UpToDate Contents
全文を閲覧するには購読必要です。 To read the full text you will need to subscribe.
- 1. 遠位（I型）および近位（II型）尿細管性アシドーシスの病因および診断 etiology and diagnosis of distal type 1 and proximal type 2 renal tubular acidosis
- 2. 尿細管性アシドーシスの概要 overview of renal tubular acidosis
- 3. 幼児および小児における尿細管性アシドーシスの病因および臨床症状 etiology and clinical manifestations of renal tubular acidosis in infants and children
- 4. 小児における慢性腎臓病管理の概要 overview of the management of chronic kidney disease in children
- 5. シスチン蓄積症 cystinosis
English Journal
- Ifosfamide-induced Fanconi Syndrome and Desmopressin-responsive Nephrogenic Diabetes Insipidus.
- Kamran SC, Pendergraft WF, Harmon DC, Rubin MF.SourceHarvard Medical School, Boston, Mass.
- The American journal of medicine.Am J Med.2013 Jul;126(7):e7-8. doi: 10.1016/j.amjmed.2013.02.005. Epub 2013 May 16.
- PMID 23684064
- Renal Fanconi syndrome associated with monoclonal κ free light chain in a patient with Waldenström macroglobulinemia.
- Ugai T, Tsuda K, Sugihara H, Nishida Y, Yamakura M, Takeuchi M, Matsue K.SourceDepartment of Haematology, Kameda Medical Centre, Kamogawa, Chiba, Japan. harukakanata58@yahoo.co.jp.
- British journal of haematology.Br J Haematol.2013 Jul;162(1):1. doi: 10.1111/bjh.12398.
- PMID 23758066
- γ-Secretase inhibition promotes fibrotic effects of albumin in proximal tubular epithelial cells.
- Slattery C, Jang Y, Kruger WA, Hryciw DH, Lee A, Poronnik P.SourceUCD School of Biomolecular and Biomedical Sciences, UCD Conway Institute, University College Dublin, Belfield, Ireland.
- British journal of pharmacology.Br J Pharmacol.2013 Jul;169(6):1239-51. doi: 10.1111/bph.12214.
- BACKGROUND AND PURPOSE: Albuminuria is an important biomarker of renal dysfunction and is a major mediator of renal damage and fibrosis during kidney disease. The mechanisms underlying albumin-induced renal fibrosis remain unclear. There has been significant interest in γ-secretase activity in tubu
- PMID 23594166
Japanese Journal
- Involvement of autophagy in the pharmacological effects of the mTOR inhibitor everolimus in acute kidney injury.
- Nakagawa Shunsaku,Nishihara Kumiko,Inui Ken-Ichi,Masuda Satohiro
- European journal of pharmacology 696(1-3), 143-154, 2012-12-05
- … however, renal LC3-II levels increased after administration of everolimus to rats subjected to ischemia-reperfusion or cisplatin treatment. … Simultaneously, increased signals for kidney injury molecule-1 and single-stranded DNA and decreased signals for Ki-67 in the proximal tubules were observed after treatment with everolimus, indicating that everolimus diminished renal function after acute tubular injury. …
- NAID 120004996384
- イタイイタイ病の現状と今後 (ミニ特集 カドミウム研究の現状と今後の展望 : 疫学研究から分子機構まで)
- 青島 恵子
- 日本衛生学雑誌 67(4), 455-463, 2012-09
- NAID 40019452034
Related Links
- 1. Pediatr Nephrol. 2005 Jan;20(1):86-8. Epub 2004 Nov 10. Proximal renal tubular dysfunction in primary distal renal tubular acidosis. Watanabe T. Department of Pediatrics, Niigata City General Hospital, 2-6-1 Shichikuyama, Niigata ...
- Proximal renal tubular function was studied in 11 patients with severe burn injury. Creatinine clearance was normal or increased in ten patients. Fractional exc ... Proximal Renal Tubular Dysfunction in Severe Burns John Lindquist ...
Related Pictures
★リンクテーブル★
| リンク元 | 「ファンコーニ症候群」「de Toni-Debre-Fanconi syndrome」「renal Fanconi syndrome」 |
| 関連記事 | 「dysfunction」「tubular」「proximal」「renal tubular」「renal」 |
「ファンコーニ症候群」
- 英
- Fanconi's syndrome, Fanconi syndrome
- 同
- ファンコニ症候群、ファンコニー症候群、Fanconi症候群、近位腎尿細管機能障害 proximal renal tubular dysfunction、デトーニ・ドゥブレ・ファンコニ症候群 De Toni-Debre-Fanconi syndrome、腎ファンコニー症候群 renal Fanconi syndrome
- 関
- 腎尿細管転送障害症、尿細管性アシドーシス、近位尿細管
概念
- 以下の病態の総称 ： 近位尿細管の障害 → アミノ酸 ＋ 糖 ＋ リン酸 などの漏出 ＆ 近位尿細管アシドーシス(RTA I)
原因
- 参考1,2
- 先天性
- 後天性
- 薬物
- 症候性
病態
- 近位尿細管の障害により、吸収されるべき分子が尿中に排出され、その結果として生じる血液検査、尿検査、様々な症候を呈する。
- 血液検査：低リン血症、低カルシウム血症、低カリウム血症、低尿酸血症
- 尿検査：腎性糖尿、汎アミノ酸尿、尿細管性蛋白尿(β2ミクログロブリン)、高リン酸尿症
参考
- 1. SPE.606
- 2. Etiology and clinical manifestations of renal tubular acidosis in infants and children - uptodate [1]
「de Toni-Debre-Fanconi syndrome」
デトーニ・ドゥブレ・ファンコニー症候群、デトーニ・ドゥブレ・ファンコニ症候群、de Toni-Debre-Fanconi症候群
「renal Fanconi syndrome」
「dysfunction」
- n.
- vi
- 機能不全に陥る
- 関
- barrier、damage、difficulty、disorder、disturbance、foe、functional disorder、functional impairment、hindrance、hypofunction、impair、impairment、impediment、incompetence、insufficiency、lesion、malfunction、obstacle、stun
「tubular」
- adj.
- 尿細管の、細尿管の、管状の
「proximal」
- adj.
- 近位の、基部の
「renal tubular」
- 腎尿細管の、尿細管の
「renal」
- adj.
- 腎臓の、腎性の、腎の