末梢神経系作用薬

WordNet

(physical chemistry) a sample of matter in which substances in different phases are in equilibrium; "in a static system oil cannot be replaced by water on a surface"; "a system generating hydrogen peroxide"
instrumentality that combines interrelated interacting artifacts designed to work as a coherent entity; "he bought a new stereo system"; "the system consists of a motor and a small computer"
a group of independent but interrelated elements comprising a unified whole; "a vast system of production and distribution and consumption keep the country going" (同)scheme
a complex of methods or rules governing behavior; "they have to operate under a system they oppose"; "that language has a complex system for indicating gender" (同)system of rules
a group of physiologically or anatomically related organs or parts; "the body has a system of organs for digestion"
a procedure or process for obtaining an objective; "they had to devise a system that did not depend on cooperation"
the living body considered as made up of interdependent components forming a unified whole; "exercise helped him get the alcohol out of his system"
a substance that exerts some force or effect
a businessman who buys or sells for another in exchange for a commission (同)factor, broker
any agent or representative of a federal agency or bureau (同)federal agent
a representative who acts on behalf of other persons or organizations
an active and efficient cause; capable of producing a certain effect; "their research uncovered new disease agents"
how long something has existed; "it was replaced because of its age"
a time of life (usually defined in years) at which some particular qualification or power arises; "she was now of school age"; "tall for his eld" (同)eld
begin to seem older; get older; "The death of his wife caused him to age fast"
make older; "The death of his child aged him tremendously"
related to the key issue but not of central importance; "a peripheral interest"; "energy is far from a peripheral issue in the economy"; "peripheral issues"
(computer science) electronic equipment connected by cable to the CPU of a computer; "disk drives and printers are important peripherals" (同)computer peripheral, peripheral device
on or near an edge or constituting an outer boundary; the outer area; "Russias peripheral provinces"; "peripheral suburbs"
easily agitated; "a nervous addict"; "a nervous thoroughbred"
of or relating to the nervous system; "nervous disease"; "neural disorder" (同)neural

PrepTutorEJDIC

〈C〉(関連した部分から成る)『体系』,系統,組織[網],装置 / 〈C〉(教育・政治などの)『制度』,機構;《the~》体制 / 〈C〉(思想・学問などの)『体系』,学説 / 〈C〉(…の)『方法』,方式,やり方《+of doing》 / 〈U〉正しい方針(筋道,順序) / 〈U〉《the~》(身体の)組織,系統 / 〈U〉《the~,one's~》身体,全身
『代理人』;周旋人 / 働き(作用)を起こすもの;作用物,薬剤 / (政府機関,特にFBI,CIAなどの)部員,機関員
〈U〉(一般に)『年齢』,寿命;〈C〉(個々の)『年齢』,年 / 〈U〉成年(おとなとしての資格・権利を得る年齢;通例18または21歳) / 〈U〉『老齢』;《集合的に》老人たち / 〈U〉(人生の)『一時期』;〈C〉世代(generation) / 〈U〉〈C〉《しばしばA-》(歴史上の)『時代』 / 〈C〉《話》長い間 / 年をとる,ふける;〈物が〉古くなる / 〈年〉'を'とらせる;〈物〉'を'古びさせる
周囲の; 周辺（装置）の・末梢的な・重要でない; （...に比べて）瑣末な (to); 【医】末端部の; コンピュータの周辺装置
『神経の』 / 『神経質な』,神経過敏な / 『心配な』,不安な

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1. 神経系のライム病 nervous system lyme disease
2. 二次性中枢神経系リンパ腫の臨床症状および診断 clinical presentation and diagnosis of secondary central nervous system lymphoma
3. 中枢神経系病変を有するHIV感染患者に対するアプローチ approach to hiv infected patients with central nervous system lesions
4. 成人における中枢神経系の原発性血管炎 primary angiitis of the central nervous system in adults
5. 中枢神経系シャントおよび他のデバイスの感染 infections of central nervous system shunts and other devices

English Journal

Control of spasticity in a multiple sclerosis model using central nervous system-excluded CB1 cannabinoid receptor agonists.

Pryce G, Visintin C, Ramagopalan SV, Al-Izki S, De Faveri LE, Nuamah RA, Mein CA, Montpetit A, Hardcastle AJ, Kooij G, de Vries HE, Amor S, Thomas SA, Ledent C, Marsicano G, Lutz B, Thompson AJ, Selwood DL, Giovannoni G, Baker D.Source*Blizard Institute and †Genome Centre, Barts and the London School of Medicine and Dentistry, Queen Mary University of London, London, UK;
FASEB journal : official publication of the Federation of American Societies for Experimental Biology.FASEB J.2013 Oct 11. [Epub ahead of print]
The purpose of this study was the generation of central nervous system (CNS)-excluded cannabinoid receptor agonists to test the hypothesis that inhibition of spasticity, due to CNS autoimmunity, could be controlled by affecting neurotransmission within the periphery. Procedures included identificati
PMID 24121462

Hypertension management: rationale for triple therapy based on mechanisms of action.

Neutel JM, Smith DH.SourceOrange County Research Center, Tustin, CA, USA.
Cardiovascular therapeutics.Cardiovasc Ther.2013 Oct;31(5):251-8. doi: 10.1111/1755-5922.12015.
An estimated 25% of patients will require 3 antihypertensive agents to achieve blood pressure (BP) control; combination therapy is thus an important strategy in hypertension treatment. This review discusses the triple-therapy combination of an angiotensin receptor blocker (ARB) or direct renin antag
PMID 23121769

Pharmacology of levosimendan: inotropic, vasodilatory and cardioprotective effects.

Pathak A, Lebrin M, Vaccaro A, Senard JM, Despas F.SourceInstitut National de Sante et de Recherche Médicale (INSERM), UMR-1048, Institut des maladies métaboliques et cardiovasculaires I2MC, Toulouse, France.
Journal of clinical pharmacy and therapeutics.J Clin Pharm Ther.2013 Oct;38(5):341-9. doi: 10.1111/jcpt.12067. Epub 2013 Apr 18.
WHAT IS KNOWN AND OBJECTIVE: Positive inotropic agents are frequently used in acute decompensated heart failure (ADHF) due to left ventricular systolic dysfunction. These agents are known to improve cardiac performance and peripheral perfusion in the short-term treatment. However, several preclinica
PMID 23594161

Japanese Journal

Dietary curcumin supplementation attenuates 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) neurotoxicity in C57BL mice

HE Xi-Jun,UCHIDA Kazuyuki,MEGUMI Chiaki,TSUGE Nobuaki,NAKAYAMA Hiroyuki
Journal of Toxicologic Pathology advpub(0), 2015
… Studies in vivo and in vitro suggest that curcumin is a neuroprotective agent. … GDNF and TGFβ1 are thought to play an important role in protecting neurons from injury in the central and peripheral nervous systems. … These results suggest that long-term administration of curcumin blocks the neurotoxicity of MPTP in the nigrostriatal dopaminergic system of the mouse and that the neuroprotective effect might be correlated with the increased expression of GDNF and TGFβ1. …
NAID 130005089123

Intestinal Transmission of Prions and Role of Exosomes in Enterocytes

Ano Yasuhisa,Sakudo Akikazu,Uraki Ryuta,Kono Juri,Yukawa Masayoshi,Onodera Takashi
Food Safety 1(1), 2013005-2013005, 2013
… In these diseases, the pathogenic prion protein (PrPSc) enters the host through the gastrointestinal tract and migrates to the central nervous system, where PrPSc induces characteristic pathological changes. … In addition, since most bovine spongiform encephalopathy cases were exposed to the agent in the first six months of life, developmental alteration of the intestinal defense and immune system may also be involved in the susceptibility to infection. …
NAID 130004591215

ギラン・バレー症候群モデル動物における脊髄ミクログリアと P2X4 受容体の神経障害性疼痛への関与

今井利安,中田恵理子,井上和秀
PAIN RESEARCH 27(1), 27-36, 2012
… 　Guillain-Barré Syndrome (GBS) is an acute inflammatory demyelinating polyneuropathy, a disorder in which the bodys immune system attacks part of the peripheral nervous system. … The P2X4 receptor is an ATP-gated ion channel and known for the crucial role it plays in development of neuropathic pain following peripheral nerve injury. …
NAID 130004651929