WordNet

a tumor composed of granulation tissue resulting from injury or inflammation or infection

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1. 環状肉芽腫 granuloma annulare
2. 皮膚糸状菌（白癬）感染症 dermatophyte tinea infections
3. 顔面肉芽腫 granuloma faciale
4. 化膿性肉芽腫（小葉状毛細血管腫） pyogenic granuloma lobular capillary hemangioma
5. 歯性感染症の疫学、病因、および臨床症状 epidemiology pathogenesis and clinical manifestations of odontogenic infections

English Journal

Longstanding dental pathology in Neandertals from El Sidrón (Asturias, Spain) with a probable familial basis.

Dean MC, Rosas A, Estalrrich A, García-Tabernero A, Huguet R, Lalueza-Fox C, Bastir M, de la Rasilla M.SourceDepartment of Cell and Developmental Biology, University College London, Gower Street, London WC1E 6BT, UK. Electronic address: chris.dean@ucl.ac.uk.
Journal of human evolution.J Hum Evol.2013 Apr 21. pii: S0047-2484(13)00091-2. doi: 10.1016/j.jhevol.2013.03.004. [Epub ahead of print]
Two Neandertal specimens from El Sidrón, northern Spain, show evidence of retained left mandibular deciduous canines. These individuals share the same mitochondrial (mtDNA) haplotype, indicating they are maternally related and suggesting a potential heritable basis for these dental anomalies. Radio
PMID 23615378

The effect of docosahexaenoic acid (DHA) on expression of IL-1ß, IL-6, IL-8, and TNF-α in normal and lipopolysaccharide (LPS)-stimulated macrophages.

Solanki P, Aminoshariae A, Jin G, Montagnese TA, Mickel A.AbstractObjective: Differentiated macrophages (MØ) are the resident tissue phagocytes and sentinel cells of the innate immune response. These cells are major constituents of periapical granulomas. Current studies indicate these activated cells as the source of bone-resorbing cytokines in the periapical granuloma. Periapical inflammation can be mediated by proinflammatory cytokines like interleukin 1ß (IL-1ß), tumor necrosis factor α (TNF-α), IL-6, and IL-8. Reducing the production of these cytokines may be beneficial for the treatment of periapical lesions. Oils rich in omega-3 fatty acids like docosahexaenoic acid (DHA) have been linked with anti-resorptive and bone-protective effects. The purpose of this investigation was to study the effect of DHA on the expression of these cytokines by normal and lipopolysaccharide (LPS)-treated MØ. We hypothesized that pretreatment of MØ with DHA decreases the expression of pro-inflammatory cytokines induced by LPS-treated MØ. Method and Materials: THP-1 monocytes were cultured and differentiated into MØ. DHA was added to MØ in a dose-dependent manner. MØ samples were added to the following groups: Group 1, ethanol alone as a solvent control; Group 2, 10 µg/ml of DHA (D1); Group 3, 20 µg/ml of DHA (D2); Group 4, 10 µg/ml of DHA + LPS (DL1); Group 5, 20 µg/ml of DHA + LPS (DL2); Group 6, LPS alone. Reverse transcriptase-PCR (RT-PCR) followed by ImageJ analysis was used to measure cytokine expression. Results: The results show that IL-1ß and TNF-α levels for DL and DHA (basal) were significantly lower than the levels in LPS alone. IL-6 was increased in the DL groups. There was no significant change for IL-8. Conclusion: DHA at higher concentrations may selectively decrease proinflammatory cytokine production of IL-1ß and TNF-α. More studies are needed to verify the anti-inflammatory therapeutic action of agents like DHA omega-3 fatty acids.
Quintessence international (Berlin, Germany : 1985).Quintessence Int.2013 Mar 27. doi: 10.3290/j.qi.a29502. [Epub ahead of print]
Objective: Differentiated macrophages (MØ) are the resident tissue phagocytes and sentinel cells of the innate immune response. These cells are major constituents of periapical granulomas. Current studies indicate these activated cells as the source of bone-resorbing cytokines in the periapical gra
PMID 23534044

Japanese Journal

Radicular cyst and granuloma : A clinicopathological study of 1590 cases and a literature review

Sanuki T,Matsuzaka K,Inoue K [他]
日本口腔検査学会雑誌 6(1), 44-49, 2014
NAID 40020149565

Radiological Evaluation of Human Dentin Autografts in Bangladesh

Arafat Kabir Md.,Murata Masaru,Kusano Koaru,Mohammad Zakaria Sayed,Hena Mohammad Noor Abu,Khuda Fazle,Hossain Iqbal,Sultana Shamima,Saito Takashi
Journal of Hard Tissue Biology 23(3), 363-370, 2014
… In Case 1, a 29 year-old male presented with an infected periapical lesion involving #11 and #12. … Root canal treatment followed by periapical surgery were done to remove the lesion. … The pathological diagnosis was radicular granuloma. …
NAID 130004848430

中世オホーツク文化人骨の生活誌

石田肇,下田靖,米田穣,内藤裕一,長岡朋人
北海道大学総合博物館研究報告 6, 109-115, 2013-03
… Excessive amounts of secondary cementum were deposited on the root surface as a result of radicular granuloma. … Pulp exposure through extreme wear very likely resulted in bacterial infection of dental pulp and periapical tissue. …
NAID 120005228561