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- 1. 炎症性乳癌：病理および分子学的病因 inflammatory breast cancer pathology and molecular pathogenesis
- 2. 大腸癌の病理および予後決定因子 pathology and prognostic determinants of colorectal cancer
- 3. 悪性神経膠腫の病因と分子生物学 pathology and molecular pathogenesis of diffuse gliomas
- 4. 古典的カポジ肉腫：疫学、危険因子、病理、および分子学的病因 classic kaposi sarcoma epidemiology risk factors pathology and molecular pathogenesis
- 5. 神経学的障害児における胎盤病理学 placental pathology in cases of neurologically impaired infants
English Journal
- Epidemiology and disease burden of pathologic myopia and myopic choroidal neovascularization: an evidence-based systematic review.
- Wong TY1, Ferreira A2, Hughes R3, Carter G3, Mitchell P4.Author information 1Singapore Eye Research Institute, Singapore National Eye Centre, National University of Singapore, Singapore. Electronic address: ophwty@nus.edu.sg.2Novartis Pharma AG, Basel, Switzerland.3Value Demonstration Practice, Oxford PharmaGenesis Ltd, Oxford, United Kingdom.4Centre for Vision Research, Westmead Millennium Institute, University of Sydney, Sydney, Australia.AbstractPURPOSE: To summarize the epidemiology of pathologic myopia and myopic choroidal neovascularization (CNV) and their impact on vision.
- American journal of ophthalmology.Am J Ophthalmol.2014 Jan;157(1):9-25.e12. doi: 10.1016/j.ajo.2013.08.010. Epub 2013 Oct 5.
- PURPOSE: To summarize the epidemiology of pathologic myopia and myopic choroidal neovascularization (CNV) and their impact on vision.DESIGN: Systematic literature review of all English-language studies evaluating the epidemiology and visual burden of pathologic myopia or myopic CNV.METHODS: PubMed a
- PMID 24099276
- Sustained inhibition of neovascularization in vldlr-/- mice following intravitreal injection of cerium oxide nanoparticles and the role of the ASK1-P38/JNK-NF-κB pathway.
- Cai X, Seal S, McGinnis JF.Author information Department of Ophthalmology, University of Oklahoma Health Sciences Center, Oklahoma City, OK 73104, USA. Electronic address: xue-cai@ouhsc.edu.AbstractCerium oxide nanoparticles (nanoceria) are direct antioxidants; they inhibit pathological neovascularization following a single intravitreal injection into new born very low density lipoprotein receptor knockout (vldlr(-/-)) mice. However, the long-term therapeutic effects and mechanisms of nanoceria action on regression of the existing pathologic neovascularization in the eyes are unknown. We intravitreally injected P28 vldlr(-/-) mice and extended the endpoint for analysis until P70. The data demonstrate that nanoceria sustained their therapeutic function up to 6 weeks. Multiple parameters for nanoceria effects were examined including: regression of existing abnormal blood vessels, reduction of vascular leakage, down-regulation of the expression of vascular endothelial growth factor (VEGF), acrolein, glial fibrillary acidic protein (GFAP) and caspase 3 as well as up-regulation of the expression of rod- and cone-opsin genes. Regulation of ASK1-P38/JNK-NF-κB signaling pathway by nanoceria was investigated. Our data demonstrated that a single intravitreal injection of nanoceria in P28 vldlr(-/-) mice produced sustained regression of existing oxidative stress-induced neovascularizations, prevented blood vessel leakage and inhibited apoptosis via down-regulation of the ASK1-P38/JNK-NF-κB signaling pathway.
- Biomaterials.Biomaterials.2014 Jan;35(1):249-58. doi: 10.1016/j.biomaterials.2013.10.022. Epub 2013 Oct 18.
- Cerium oxide nanoparticles (nanoceria) are direct antioxidants; they inhibit pathological neovascularization following a single intravitreal injection into new born very low density lipoprotein receptor knockout (vldlr(-/-)) mice. However, the long-term therapeutic effects and mechanisms of nanoceri
- PMID 24140045
- Skin-scanning technique for superficial blood flow imaging using a high-frequency ultrasound system.
- Chen JJ, Cheng CH, Yeh CK.Author information Department of Biomedical Engineering and Environmental Sciences, National Tsing Hua University, Hsinchu, Taiwan.AbstractIn this paper we propose a skin-scanning technique with a high-frequency ultrasound imaging system that enables images to be acquired at the fixed depth of field of a single-element focused transducer along the profile of an object contour by simultaneously moving the transducer in the horizontal and vertical directions. The scanning path, which closely parallels the profile of the object contour, was determined from the intensity difference between an object and the background in a brightness-mode image. The transducer moved along the profile of the object contour while maintaining a constant distance interval between adjacent pairs of ultrasonic signals in the horizontal direction. The image was then reconstructed by applying an alignment process to eliminate the distortion. The performance of skin-scanning technique was verified in vitro experiment using an arc-shaped phantom and the results showed a percentage error of 0.55% for the volumetric blood flow estimates. Moreover, in vivo experiment on a subcutaneous tumor was also performed. The results indicated that the proposed technique can accurately estimate the blood flow information along the profile of the object contour and avoid distortion of the morphology of blood vessels. The skin-scanning technique has potential for assessing superficial blood flows and prognoses in the oncology and dermatology fields.
- Ultrasonics.Ultrasonics.2014 Jan;54(1):241-6. doi: 10.1016/j.ultras.2013.06.003. Epub 2013 Jun 29.
- In this paper we propose a skin-scanning technique with a high-frequency ultrasound imaging system that enables images to be acquired at the fixed depth of field of a single-element focused transducer along the profile of an object contour by simultaneously moving the transducer in the horizontal an
- PMID 23850423
Japanese Journal
- カリジノゲナーゼの血管新生抑制作用
- 岐阜薬科大学紀要 = The annual proceedings of Gifu Pharmaceutical University 63, 22-32, 2014-06-30
- NAID 120005564611
- 非医原性 parasitic myoma と考えられた一例
- 日本産科婦人科内視鏡學會雜誌 = The journal of the Japan Endoscopy Society of Obstetrics and Gynecology 28(1), 342-345, 2012-08-01
- NAID 10031121786
- 4AAQB inhibits vascular endothelial growth factor-induced angiogenesis in in vitro and in vivo model
- 日本毒性学会学術年会 39.2(0), AP-169, 2012
- NAID 130005009107
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★リンクテーブル★
| リンク元 | 「病的血管新生」「pathological neovascularization」「pathologic angiogenesis」「pathological angiogenesis」 |
| 関連記事 | 「pathologic」 |
「病的血管新生」
- 英
- pathological angiogenesis、pathologic angiogenesis、pathological neovascularization、pathologic neovascularization
- 関
- 病理的血管新生
「pathological neovascularization」
「pathologic angiogenesis」
「pathological angiogenesis」
「pathologic」
- adj.
- 病的な、病理的な、病態的な、病理の、病態の