関: methionine-tRNA ligase

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1. ヘキソースリン酸側路およびグルタチオン代謝疾患（グルコース-6-リン酸脱水素酵素欠損症を除く） disorders of the hexose monophosphate shunt and glutathione metabolism other than glucose 6 phosphate dehydrogenase deficiency
2. 成人における皮膚筋炎および多発性筋炎の臨床症状 clinical manifestations of dermatomyositis and polymyositis in adults
3. 炎症性ミオパチーの病因 pathogenesis of inflammatory myopathies
4. 皮膚筋炎および多発性筋炎における間質性肺疾患：臨床症状および診断 interstitial lung disease in dermatomyositis and polymyositis clinical manifestations and diagnosis
5. 成人における皮膚筋炎および多発性筋炎の初期治療 initial treatment of dermatomyositis and polymyositis in adults

English Journal

Temperature dependent mistranslation in a hyperthermophile adapts proteins to lower temperatures.

Schwartz MH1, Pan T2.
Nucleic acids research.Nucleic Acids Res.2016 Jan 8;44(1):294-303. doi: 10.1093/nar/gkv1379. Epub 2015 Dec 10.
All organisms universally encode, synthesize and utilize proteins that function optimally within a subset of growth conditions. While healthy cells are thought to maintain high translational fidelity within their natural habitats, natural environments can easily fluctuate outside the optimal functio
PMID 26657639

A dual fluorescent reporter for the investigation of methionine mistranslation in live cells.

Gomes AC1, Kordala AJ1, Strack R1, Wang X1, Geslain R1, Delaney K1, Clark WC1, Keenan R1, Pan T2.
RNA (New York, N.Y.).RNA.2016 Jan 4. [Epub ahead of print]
In mammalian cells under oxidative stress, the methionyl-tRNA synthetase (MetRS) misacylates noncognate tRNAs at frequencies as high as 10% distributed among up to 28 tRNA species. Instead of being detrimental for the cell, misincorporation of methionine residues in the proteome reduces the risk of
PMID 26729921

Assembly of Multi-tRNA Synthetase Complex via Heterotetrameric Glutathione Transferase-homology Domains.

Cho HY1, Maeng SJ1, Cho HJ1, Choi YS1, Chung JM2, Lee S2, Kim HK3, Kim JH3, Eom CY4, Kim YG5, Guo M6, Jung HS2, Kang BS7, Kim S8.
The Journal of biological chemistry.J Biol Chem.2015 Dec 4;290(49):29313-28. doi: 10.1074/jbc.M115.690867. Epub 2015 Oct 15.
Many multicomponent protein complexes mediating diverse cellular processes are assembled through scaffolds with specialized protein interaction modules. The multi-tRNA synthetase complex (MSC), consisting of nine different aminoacyl-tRNA synthetases and three non-enzymatic factors (AIMP1-3), serves
PMID 26472928

Japanese Journal

1P125 X線結晶構造解析によるメチオニルtRNA合成酵素のtRNA認識機構の解明(核酸結合蛋白質))

生物物理 45(SUPPLEMENT_1), S63, 2005-10-19
NAID 110004571106

Nucleolar localization of human methionyl-tRNA synthetase and its role in ribosomal RNA synthesis

J. Cell. Biol. 149, 567-574, 2000
NAID 30017395480

CHOP/GADD153 and methionyl-tRNA synthetase (MetRS) genes overlap in a conserved region that controls mRNA stability

Biochem Biophys Res Commun 262, 31-38, 1999
NAID 30017796521

「メチオニルtRNA合成酵素」

　　[★]

英: methionyl-tRNA synthetase
関: メチオニンtRNAリガーゼ、メチオニルtRNAシンテターゼ

「メチオニルtRNAシンテターゼ」

　　[★]

英: methionyl-tRNA synthetase
関: メチオニルtRNA合成酵素

「methionine-tRNA ligase」

　　[★]

メチオニンtRNAリガーゼ

関: methionyl-tRNA synthetase

「synthetase」

　　[★]

n.

(ATPやNADを必要とする2分子連結酵素リガーゼの別名)シンテターゼ、シンセターゼ、連結酵素、合成酵素

関: ligase、synthase

「tRNA」

　　[★] トランスファーRNA, transfer RNA, 転位RNA

「tRNAs」

　　[★] トランスファーRNA transfer RNAs

リンク元	「メチオニルtRNA合成酵素」「メチオニルtRNAシンテターゼ」「methionine-tRNA ligase」
関連記事	「synthetase」「tRNA」「tRNAs」

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案内

methionyl-tRNA synthetase

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Japanese Journal

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★リンクテーブル★

「メチオニルtRNA合成酵素」

「メチオニルtRNAシンテターゼ」

「methionine-tRNA ligase」

「synthetase」

「tRNA」

「tRNAs」