関: MMP-10

WordNet

(geology) amass of fine-grained rock in which fossils, crystals, or gems are embedded
mold used in the production of phonograph records, type, or other relief surface
the body substance in which tissue cells are embedded (同)intercellular substance, ground_substance
(mathematics) a rectangular array of quantities or expressions set out by rows and columns; treated as a single element and manipulated according to rules
an enclosure within which something originates or develops (from the Latin for womb)
the formative tissue at the base of a nail

PrepTutorEJDIC

（複数形 matrices, ～・es）(発生・成長の)母体 / 鋳型・模型;(レコードの)原盤;(活字の)母型,字母 / (金属・化石・宝石などの含んだ)母岩・《古》子宮・基盤; (細胞)細胞間質; (地学)基質; (印)字母; 紙型; 鋳型; (鉱)母岩; (数)行列; (コンピュータ)マトリックス (入力導線と出力導線の回路網); (言)母型文（matrix sentence）
マトリクシング(4チャンネルに再生転換できる2チャンネルの録音方式)

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出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2016/01/22 23:53:41」(JST)

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Stromelysin 2 (EC 3.4.24.22, matrix metalloproteinase 10, transin 2, proteoglycanase 2) is an enzyme.^[1]^[2]^[3] This enzyme catalyses the following chemical reaction

Similar to stromelysin 1, but action on collagen types III, IV and V is weak

This enzyme belongs to the peptidase family M10 (interstitial collagenase family).

References

^ Breathnach, R., Matrisian, L.M., Gesnel, M.-C. and Leroy, P. (1987). "Sequences coding for part of oncogene-induced transin are highly conserved in a related rat gene". Nucleic Acids Res. 15: 1139–1151. doi:10.1093/nar/15.3.1139. PMID 3547333.
^ Muller, D., Quantin, B., Gesnel, M.-C., Millon-Collard, R., Abecassis, J. and Breathnach, R. (1988). "The collagenase gene family in humans consists of at least four members". Biochem. J. 253 (1): 187–192. PMC 1149273. PMID 2844164.
^ Nicholson, R., Murphy, G. and Breathnach, R. (1989). "Human and rat malignant-tumor-associated mRNAs encode stromelysin-like metalloproteinases". Biochemistry 28 (12): 5195–5203. doi:10.1021/bi00438a042. PMID 2548603.

External links

Stromelysin 2 at the US National Library of Medicine Medical Subject Headings (MeSH)

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English Journal

Eicosapentaenoic acid and docosahexaenoic acid inhibit macrophage-induced gastric cancer cell migration by attenuating the expression of matrix metalloproteinase 10.

Wu MH, Tsai YT, Hua KT, Chang KC, Kuo ML, Lin MT.SourceDepartment of Surgery, Institute of Toxicology, National Taiwan University, Taipei 100, Taiwan.
The Journal of nutritional biochemistry.J Nutr Biochem.2012 Nov;23(11):1434-9. doi: 10.1016/j.jnutbio.2011.09.004. Epub 2012 Jan 27.
Uptake of docosahexaenoic acid (DHA)/eicosapentaenoic acid (EPA) improves the treatment of cancer and reduces tumor-associated macrophage count. However, the mechanism of this relationship is still unclear. In this study, macrophages enhanced gastric cancer cell migration ability and induced the dif
PMID 22285823

Overexpression of matrix metalloproteinase 10 is associated with poor survival in patients with early stage of esophageal squamous cell carcinoma.

Liu H, Qin YR, Bi J, Guo A, Fu L, Guan XY.SourceState Key Laboratory of Oncology in Southern China, Cancer Center, Sun Yat-sen University The Third Affiliated Hospital of Guangzhou Medical University Laboratory of Surgery, The First Affiliated Hospital, Sun Yat-sen University Guangdong Lung Cancer Institute, Guangdong General Hosipital, Guangdong Academy of Medical Sciences, Guangzhou Department of Clinical Oncology, The First Affiliated Hospital, Zhengzhou University, Zhengzhou Departments of Clinical Oncology, The University of Hong Kong, Hong Kong, China.
Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus / I.S.D.E.Dis Esophagus.2012 Sep;25(7):656-663. doi: 10.1111/j.1442-2050.2011.01284.x. Epub 2011 Nov 28.
Matrix metallopeptidase 10 (MMP10) is frequently expressed and correlates closely with metastasis and poor prognosis in various human cancers. However, the significance of MMP10 expression in esophageal squamous cell carcinoma (ESCC) and its role in ESCC progression remains unclear. In this report,
PMID 22121946

Japanese Journal

Thermodynamic analysis of ionizable groups involved in the catalytic mechanism of human matrix metalloproteinase 7 (MMP-7).

Takeharu Hitoshi,Yasukawa Kiyoshi,Inouye Kuniyo
Biochimica et biophysica acta 1814(12), 1940-1946, 2011-12
… Human matrix metalloproteinase 7 (MMP-7) exhibits a broad bell-shaped pH-dependence with the acidic and alkaline pK(e) (pK(e1) and pK(e2)) values of about 4 and 10. …
NAID 120003644370

Relationship Between Myocardial Redox State and Matrix Metalloproteinase Activity in Patients on Left Ventricular Assist Device Support

CARUSO Raffaele,CASELLI Chiara,BORONI Chiara,CAMPOLO Jonica,MILAZZO Filippo,CABIATI Manuela,RUSSO Claudio,PAROLINI Marina,GIANNESSI Daniela,FRIGERIO Maria,PARODI Oberdan
Circulation journal : official journal of the Japanese Circulation Society 75(10
… These data support a role of GSH cycle in modulating the extracellular matrix in end-stage heart failure patients supported by LVAD. …
NAID 10029459423

「MMP-10」

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PMC	articles
PubMed	articles
NCBI	proteins

Stromelysin 2
Identifiers
EC number	3.4.24.22
CAS number	140610-48-6
Databases
IntEnz	IntEnz view
BRENDA	BRENDA entry
ExPASy	NiceZyme view
KEGG	KEGG entry
MetaCyc	metabolic pathway
PRIAM	profile
PDB structures	RCSB PDB PDBe PDBsum
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PMC	articles
PubMed	articles
NCBI	proteins

　　[★]

マトリックスメタロプロテアーゼ10

関: matrix metalloproteinase 10

「マトリックスメタロプロテアーゼ10」

　　[★]

英: matrix metalloproteinase 10、MMP-10

「matrix metalloproteinase」

　　[★] マトリックスメタロプロテアーゼ MMP

「metalloproteinase」

　　[★] メタロプロテアーゼ

「metalloproteinases」