WordNet

characterized or caused by inflammation; "an inflammatory process"; "an inflammatory response"

PrepTutorEJDIC

炎症を起こす,炎症性の / 憤激させる,扇動的な

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出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2016/09/19 02:55:37」(JST)

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Polyarthritis is any type of arthritis that involves 5 or more joints simultaneously. It is usually associated with autoimmune conditions and may be experienced at any age and is not sex specific.

Causes

Polyarthritis is most often caused by an auto-immune disorder such as rheumatoid arthritis, amyloidosis, psoriatic arthritis, and lupus erythematosus but can also be caused by infection with an alphavirus such as chikungunya virus and Ross River virus. This condition is termed alphavirus polyarthritis syndrome. Sindbis virus, which is endemic in Northern Europe, Africa, the Middle East, and Australia, is the most widely distributed of the alphaviruses causing polyarthritis, though infection is usually mild or asymptomatic.

Associated conditions

It may be associated with bilateral edema in lower limbs, pain and joint swelling. Sometimes there is previous history of inflammatory joint problems and bilateral edema of lower limbs.

Alphavirus Polyarthritis Syndrome has an incubation period of 3–21 days, depending on the specific virus, with either a gradual or sudden onset of fever, arthralgias, headache, and lymphadenitis and conjunctivitis in some forms. A maculopapular rash may present 4–8 days post symptom onset and may be accompanied by an increase in fever. Joint pains associated with this condition may recur for many months after initial illness for up to a year.

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1. 成人における多関節痛の評価 evaluation of the adult with polyarticular pain
2. 成人における未分化の早期炎症性関節炎 undifferentiated early inflammatory arthritis in adults
3. 多関節型若年性特発性関節炎：臨床症状、診断および合併症 polyarticular juvenile idiopathic arthritis clinical manifestations diagnosis and complications
4. 関節リウマチの診断および鑑別診断 diagnosis and differential diagnosis of rheumatoid arthritis
5. 多関節型若年性特発性関節炎：治療 polyarticular juvenile idiopathic arthritis treatment

English Journal

Mechanistic insight into the attenuation of gouty inflammation by Taiwanese green propolis via inhibition of the NLRP3 inflammasome.

Hsieh CY1, Li LH2, Rao YK1, Ju TC3, Nai YS1, Chen YW1, Hua KF1,4,5.
Journal of cellular physiology.J Cell Physiol.2019 Apr;234(4):4081-4094. doi: 10.1002/jcp.27204. Epub 2018 Oct 28.
PMID 30370562

Anti-inflammatory effects of Ang-(1-7) via TLR4-mediated inhibition of the JNK/FoxO1 pathway in lipopolysaccharide-stimulated RAW264.7 cells.

Jiang M1, Huang W1, Wang Z1, Ren F1, Luo L1, Zhou J1, Yan R1, Xia N1, Tang L2.
Developmental and comparative immunology.Dev Comp Immunol.2019 Mar;92:291-298. doi: 10.1016/j.dci.2018.11.009. Epub 2018 Nov 17.
PMID 30458182

MiR-3926 inhibits synovial fibroblasts proliferation and inflammatory cytokines secretion through targeting toll like receptor 5.

Fu D1, Xiao C1, Xie Y1, Gao J1, Ye S2.
Gene.Gene.2019 Mar 1;687:200-206. doi: 10.1016/j.gene.2018.11.014. Epub 2018 Nov 6.
PMID 30412746

Japanese Journal

Ablation of the Ccr2 gene exacerbates polyarthritis in interleukin-1 receptor antagonist-deficient mice

Fujii Hiroshi,Baba Tomohisa,Ishida Yuko,Kondo Toshikazu　,Yamagishi Masakazu　,Kawano Mitsuhiro　,Mukaida Naofumi　
Arthritis and Rheumatism 63(1), 96-106, 2011-01
… Moreover, the double-deficient mice exhibited enhanced expression of the neutrophilic chemokines keratinocyte chemoattractant and macrophage inflammatory protein 2 (MIP-2), compared with Il1rn-deficient mice. …
NAID 120002754103