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English Journal

Characterization and biological effects of two polysaccharides isolated from Acanthopanax sciadophylloides.

Lee JB1, Tanikawa T2, Hayashi K2, Asagi M3, Kasahara Y3, Hayashi T2.
Carbohydrate polymers.Carbohydr Polym.2015 Feb 13;116:159-66. doi: 10.1016/j.carbpol.2014.04.013. Epub 2014 Apr 19.
Two polysaccharides abbreviated ANP and AAP were isolated from the young buds of Acanthopanax sciadophylloides. ANP consisted of L-arabinose, D-mannose, D-glucose and D-galactose in a ratio of ca 1.0:2.6:2.5:1.4 and its weight average molecular weight (Mw) was 1.07×10(4). AAP consisted of L-arabino
PMID 25458285

Structure Characterization of a Novel Polysaccharide from Dictyophora indusiata and Its Macrophage Immunomodulatory Activities.

Liao W1, Luo Z, Liu D, Ning Z, Yang J, Ren J.
Journal of agricultural and food chemistry.J Agric Food Chem.2015 Jan 21;63(2):535-44. doi: 10.1021/jf504677r. Epub 2015 Jan 6.
A novel polysaccharide, here named DP1, was isolated from the fruiting body of Dictyophora indusiata using a water extraction method. Structure characterization revealed that DP1 had an average molecular weight of 1132 kDa and consisted of glucose (56.2%), galactose (14.1%), and mannose (29.7%). The
PMID 25525995

Synthesis of tumor-associated MUC1-glycopeptides and their multivalent presentation by functionalized gold colloids.

Tavernaro I1, Hartmann S, Sommer L, Hausmann H, Rohner C, Ruehl M, Hoffmann-Roeder A, Schlecht S.
Organic & biomolecular chemistry.Org Biomol Chem.2015 Jan 7;13(1):81-97. doi: 10.1039/c4ob01339e.
The mucin MUC1 is a glycoprotein involved in fundamental biological processes, which can be found over-expressed and with a distinctly altered glycan pattern on epithelial tumor cells; thus it is a promising target structure in the quest for effective carbohydrate-based cancer vaccines and immunothe
PMID 25212389

Kim Jung-Hoon,Shin Eun-Hye,Lee Hak-Yong,Lee Bong-Gun,Park Sang-Hoon,Moon Dae-In,Goo Gyo-Chang,Kwon Dae-Young,Yang Hye-Jeong,Kim Ok-Jin,Oh Hong-Geun
Experimental Animals 62(3), 247-253, 2013
… In this study, the immunostimulating properties of A. … sessiliflorus has not only a host defense effect but also a stress-ameliorating property, further study it will be a promising material of immunostimulating material. …
NAID 130003362960

深瀬浩一,藤本ゆかり,下山敦史 [他],田中克典
有機合成化学協会誌 70(2), 113-130, 2012-02-01
… Immunostimulating glycoconjugates from bacteria were synthesized for elucidation of the recognition with innate immune receptors. …
NAID 10030481197