immunoreceptor tyrosine based activation motif

免疫受容活性化チロシンモチーフ

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• 1. 肥満細胞：表面受容体とシグナル伝達mast cells surface receptors and signal transduction [show details]
  … transduction. Crosslinking of Fc-epsilon-RI leads to phosphorylation of the immunoreceptor tyrosine-based activation motif (ITAM) of the cytoplasmic domain of both the beta and gamma subunits of the receptor …
• 2. 免疫不全症を引き起こすCD3／T細胞受容体複合体疾患cd3 t cell receptor complex disorders causing immunodeficiency [show details]
  …and differentiation pathway via a motif in the cytoplasmic domain called the immunoreceptor tyrosine-based activation motif (ITAM) There are a number of molecules involved in early signal transduction …
• 3. T細胞受容体シグナル伝達t cell receptor signaling [show details]
  …coreceptor cytoplasmic domains, specifically at motifs known as immunoreceptor tyrosine-based activation motifs (ITAMs). These phosphorylated ITAMs on CD3-zeta serve as binding sites for the zeta chain-associated …
• 4. ホジキンリンパ腫におけるエプスタイン・バール・ウイルスthe role of epstein barr virus in hodgkin lymphoma [show details]
  …with LMP1 in the plasma membrane of EBV-infected lymphocytes . LMP2a contains an immunoreceptor tyrosine based activation motif that resembles motifs carried by immunoglobulin molecules. Expression of LMP2a…
• 5. IgGの構造および生物学的機能structure and biologic functions of iga [show details]
  …Fc-alpha-RI, without cross-linking of the receptor, causes phosphorylation of an immunoreceptor tyrosine-based activation motif (ITAM), which in turn induces the recruitment of the tyrosine phosphatase SHP-1…

English Journal

• K1 gene transformation activities in AIDS-related and classic type Kaposi's sarcoma: Correlation with clinical presentation.

• Tamanaha-Nakasone A, Uehara K, Tanabe Y, Ishikawa H, Yamakawa N, Toyoda Z, Kurima K, Kina S, Tsuneki M, Okubo Y, Yamaguchi S, Utsumi D, Takahashi K, Arakawa H, Arasaki A, Kinjo T.
• Scientific reports. 2019 Apr;9(1)6416.
• Kaposi's sarcoma-associated herpesvirus (KSHV) causes both AIDS-related Kaposi's sarcoma (KS) and classic KS, but their clinical presentations are different, and respective mechanisms remain to be elucidated. The KSHV K1 gene is reportedly involved in tumorigenesis through the immunoreceptor tyrosin
• PMID 31015491

• Myeloid C-type lectin receptors in skin/mucoepithelial diseases and tumors.

• Tang C, Makusheva Y, Sun H, Han W, Iwakura Y.
• Journal of leukocyte biology. 2019 Apr;().
• Myeloid C-type lectin receptors (CLRs), which consist of an extracellular carbohydrate recognition domain and intracellular signal transducing motif such as the immunoreceptor tyrosine-based activation motif (ITAM) or immunoreceptor tyrosine-based inhibitory motif (ITIM), are innate immune receptors
• PMID 30964564

• Evaluation of CD33 as a genetic risk factor for Alzheimer's disease.

• Estus S, Shaw BC, Devanney N, Katsumata Y, Press EE, Fardo DW.
• Acta neuropathologica. 2019 Apr;().
• In 2011, genome-wide association studies implicated a polymorphism near CD33 as a genetic risk factor for Alzheimer's disease. This finding sparked interest in this member of the sialic acid-binding immunoglobulin-type lectin family which is linked to innate immunity. Subsequent studies found that C
• PMID 30949760

Japanese Journal

• ITAM共役型C型レクチン受容体による結核菌の認識 (特集 自然免疫に関する新規知見と発展)

• 豊永 憲司,山﨑 晶
• 臨床免疫・アレルギー科 = Clinical immunology & allergology 68(4), 395-401, 2017-10
• NAID 40021346825

• パターン認識受容体としてのC型レクチン受容体

• 三宅 靖延
• 臨床免疫・アレルギー科 = Clinical immunology & allergology 67(6), 636-641, 2017-06
• NAID 40021232421

• Construction of C35 gene bait recombinants and T47D cell cDNA library

• Yin Kun,Xu Chao,Zhao Gui-Hua,Liu Ye,Xiao Ting,Zhu Song,Yan Ge
• BioScience Trends 11(5), 550-556, 2017
• … Based on functional domain analysis, the full-length C35_1-348bp … was also truncated into two fragments C351-153bp and C35154-348bp to avoid auto-activation. … Auto-activation and toxicity of C35 baits were detected using nutritional deficient medium and X-α-Gal assays. … The transformed Y187/pGBKT7-C351-348bp line was intensively inhibited while the truncated Y187/pGBKT7-C35 lines had no auto-activation and toxicity in yeast cells. …
• NAID 130007040195

Related Links

• Immunoreceptor Tyrosine Based Activation Motif - an overview ...

Immunoreceptor Tyrosine Based Activation Motif Immunoreceptor tyrosine-based activation motif (ITAM) is an important signaling component for a number of immunoglobulin-like receptors including T-cell receptors, B-cell receptors ...

• Immunoreceptor tyrosine-based activation motif (ITAM), a ...

Immunoreceptor tyrosine-based activation motif (ITAM), a unique module linking antigen and Fc receptors to their signaling cascades. Isakov N(1). Author information: (1)Department of Microbiology and Immunology, Faculty of ...

• Immunoreceptor tyrosine‐based activation motif (ITAM), a ...

6 Journal of Leukocyte Biology Volume 61, January 1997 lmmunoreceptor tyrosine-based activation motif (ITAM), a unique module linking antigen and Fc receptors to their signaling cascades Noah lsakov Department of Microbiology ...

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★リンクテーブル★

リンク元	「免疫受容活性化チロシンモチーフ」
拡張検索	「immunoreceptor tyrosine-based activation motif」
関連記事	「base」「activation」「immunoreceptor」

「免疫受容活性化チロシンモチーフ」

　　[★]

英

immunoreceptor tyrosine based activation motif, ITAM

関

ITAM

「immunoreceptor tyrosine-based activation motif」

　　[★]

• 免疫受容活性化チロシンモチーフ

関

ITAM

「base」

　　[★]

• n.

• 基礎、基盤、根拠、基本、基底

関

basal、base、basement、basic、basis、element、elementary、evidence、foundation、fundamental、fundamentals、fundus、ground、infrastructure、reason

　 　 　 　 　 　 　 　 　 　 　 　 　 　 　 　 　 　 　 　 　

「activation」

　　[★]

• 活性化、賦活化、賦活

関

activate、activated、turn on

　 　 　

「immunoreceptor」

　　[★]

• 免疫受容体、免疫レセプター

関

immunologic receptor