WordNet

small room in which a monk or nun lives (同)cubicle
a device that delivers an electric current as the result of a chemical reaction (同)electric cell
a room where a prisoner is kept (同)jail cell, prison cell
(biology) the basic structural and functional unit of all organisms; they may exist as independent units of life (as in monads) or may form colonies or tissues as in higher plants and animals
any small compartment; "the cells of a honeycomb"
a small unit serving as part of or as the nucleus of a larger political movement (同)cadre
a hybrid cell resulting from the fusion of a lymphocyte and a tumor cell; used to culture a specific monoclonal antibody

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(刑務所の)『独房』;(修道院の)小さい独居室 / (ミツバチの)みつ房,巣穴 / 小さい部屋 / 『細胞』 / 電池 / 花粉室 / (共産党などの)細胞

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1. 成人における微小変化群の病因、臨床的特徴、および診断 etiology clinical features and diagnosis of minimal change disease in adults
2. 免疫系におけるサイトカインの役割 role of cytokines in the immune system
3. 免疫グロブリンの機能および臨床応用 function and clinical applications of immunoglobulins
4. 肺リンパ脈管筋腫症 pulmonary lymphangioleiomyomatosis
5. T細胞受容体シグナル伝達 t cell receptor signaling

English Journal

Quantification of antibody production of individual hybridoma cells by surface plasmon resonance imaging.

Stojanović I1, van der Velden TJ2, Mulder HW3, Schasfoort RB2, Terstappen LW3.
Analytical biochemistry.Anal Biochem.2015 Sep 15;485:112-8. doi: 10.1016/j.ab.2015.06.018. Epub 2015 Jun 18.
Surface plasmon resonance imaging (SPRi) is most frequently used for the label-free measurement of biomolecular interactions. Here we explore the potential of SPRi to measure antibody production of individual hybridoma cells. As a model system, cells from a hybridoma, producing monoclonal antibodies
PMID 26095397

Development of ELISA and colloidal gold immunoassay for tetrodotoxin detetcion based on monoclonal antibody.

Ling S1, Chen QA2, Zhang Y3, Wang R1, Jin N1, Pang J4, Wang S5.
Biosensors & bioelectronics.Biosens Bioelectron.2015 Sep 15;71:256-60. doi: 10.1016/j.bios.2015.04.049. Epub 2015 Apr 18.
A monoclonal hybridoma cell named 5B9 against tetrodotoxin (TTX) was obtained after fusion of myeloma SP2/0 cells with spleen cells isolated from the immunized Balb/c mice. The 5B9 monoclonal antibody (McAb) with high affinity (about 2.55 × 10(9)) is specific to TTX, and this McAb belongs to the im
PMID 25913446

BHRF1 exerts an antiapoptotic effect and cell cycle arrest via Bcl-2 in murine hybridomas.

Milián E1, Prats E2, Cairó JJ3, Gòdia F3, Vives J4.
Journal of biotechnology.J Biotechnol.2015 Sep 10;209:58-67. doi: 10.1016/j.jbiotec.2015.06.379. Epub 2015 Jun 7.
Apoptosis has been widely studied in order to find methods to increase the life-span and production performance in large-scale animal cell cultures. The use of anti-apoptotic genes has emerged as an efficient method to reduce apoptosis in a variety of biotechnological relevant cell lines, including
PMID 26057602

Japanese Journal

Generation and Application of Monoclonal Antibodies Specific for the Envelope Protein pORF132 of Cyprinid Herpesvirus 3

魚病研究 51(1), 15-22, 2016
NAID 130005138648

2P-078 受容体特異的立体構造認識モノクローナル抗体の効率的作製(抗体工学,一般講演)

日本生物工学会大会講演要旨集 67, 194, 2015-09-25
NAID 110010009165

Establishment of Sandwich Enzyme-Linked ImmunoSorbent Assay (ELISA) System for Quantitation of CD81

Journal of Hard Tissue Biology 24(4), 401-404, 2015
NAID 130005104333

Related Links

Hybridomas - ATCC

Hybridomas. Hybridomas are immortalized cells derived from the fusion of B lymphoblasts with a myeloma fusion partner. Some hybridomas in the ATCC collection are somatic cell hybrids. These cells are capable of producing immunoglobulins that are specific for viral, bacterial or cellular targets.

Hybridoma Technology | Sino Biological

Hybridoma cell lines are formed via fusion between a short-lived antibody-producing B cell and an immortal myeloma cell. Each hybridoma constitutively expresses a large amount of one specific mAb, and favored hybridoma cell lines can be cryopreserved for long-lasting mAb production .

Hybridoma - an overview | ScienceDirect Topics

To separate B cells (immortal cells) and hybridoma cells (also immortal cells), specific types of myeloma cells are used. Myeloma cells do not secrete any antibody themselves and lack the hypoxanthine-guanine phosphoribosyltransferase (HGPRT) gene, making them sensitive to a medium containing hypoxanthine–aminopterin–thymidine (HAT).