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1. 限局性結節性過形成 focal nodular hyperplasia
2. カロリー病 caroli disease
3. 原発性胆汁性肝硬変治療用ウルソデオキシコール酸の臨床試験 trials of ursodeoxycholic acid for the treatment of primary biliary cirrhosis
4. 気管支内超音波検査：技術的側面 endobronchial ultrasound technical aspects
5. 肝内胆管の消失および胆管消失症候群 hepatic ductopenia and vanishing bile duct syndrome

Bile ductal injury and ductular reaction are frequent phenomena with different significance in autoimmune hepatitis.

Verdonk RC1,2, Lozano MF3, van den Berg AP1, Gouw AS3.
Liver international : official journal of the International Association for the Study of the Liver.Liver Int.2016 Feb 5. doi: 10.1111/liv.13083. [Epub ahead of print]
BACKGROUND AND AIMS: The significance of bile duct injury and ductular reaction in biopsies from autoimmune hepatitis patients is not clear. We aim to establish the prevalence and clinical relevance of both phenomena in autoimmune hepatitis.METHODS: Cases of newly diagnosed, untreated autoimmune hep
PMID 26849025

Jagged1 heterozygosity in mice results in a congenital cholangiopathy which is reversed by concomitant deletion of one copy of Poglut1 (Rumi).

Thakurdas SM1, Lopez MF1, Kakuda S2, Fernandez-Valdivia R3, Zarrin-Khameh N4, Haltiwanger RS2, Jafar-Nejad H1,5.
Hepatology (Baltimore, Md.).Hepatology.2016 Feb;63(2):550-65. doi: 10.1002/hep.28024. Epub 2015 Oct 20.
Haploinsufficiency for the Notch ligand JAG1 in humans results in an autosomal-dominant, multisystem disorder known as Alagille syndrome, which is characterized by a congenital cholangiopathy of variable severity. Here, we show that on a C57BL/6 background, jagged1 heterozygous mice (Jag1(+/-) ) exh
PMID 26235536

Alison MR1, Lin WR2.
The Journal of pathology.J Pathol.2016 Feb;238(3):371-4. doi: 10.1002/path.4667. Epub 2015 Nov 28.
The liver's ability to regenerate is indisputable; for example, after a two-thirds partial hepatectomy in rats all residual hepatocytes can divide, questioning the need for a specific stem cell population. On the other hand, there is a potential stem cell compartment in the canals of Hering, giving
PMID 26510495

Bile canalicular abnormalities in the early phase of a mouse model of sclerosing cholangitis.

Miyao Masashi,Ozeki Munetaka,Abiru Hitoshi,Manabe Sho,Kotani Hirokazu,Tsuruyama Tatsuaki,Tamaki Keiji
Digestive and liver disease 45(3), 216-225, 2013-03
… After these inflammatory changes, cholangiocytes proliferated in the portal area and formed ductular reactions. …
NAID 120005244416

向宗徳
金沢大学十全医学会雑誌 = Journal of the J◆U00FB◆zen Medical Society 121(1), 2-17, 2012-03-01
NAID 10030596010

Autophagy May Precede Cellular Senescence of Bile Ductular Cells in Ductular Reaction in Primary Biliary Cirrhosis

Sasaki Motoko,Miyakoshi Masami,Sato Yasunori,Nakanuma Yasuni
Digestive Diseases and Sciences 57(3), 660-666, 2012-03
… Given that cellular senescence is involved in the pathophysiology of ductular reaction (DR) in primary biliary cirrhosis (PBC), we examined an involvement of autophagy in DRs in PBC and control livers. … Methods: We examined immunohistochemically the expression of microtubule-associated proteins light chain 3β (LC3) as autophagy marker, p62/sequestosome-1 (p62) as autophagy-related marker in bile ductular cells in livers taken from the patients with PBC (n = 42), and control livers (n = 100). …
NAID 120003497596