arcus lipoides

WordNet

1. a continuous portion of a circle
2. a whitish deposit in the shape of an arc that is sometimes seen in the cornea (同)arcus_senilis

PrepTutorEJDIC

1. 『弧』,円弧 / 電弧(2点間を弧状に流れる電流) / 弧を描く / 電弧を生じる

Wikipedia preview

出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2014/05/09 21:57:05」(JST)

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Arcus senilis
Classification and external resources
Four representative slides of corneal arcus - arcus deposits tend to start at 6 and 12 o'clock and fill in until becoming completely circumferential. There is a thin, clear section separating the arcus from the limbus, known as the lucid interval of Vogt. Image from Zech and Hoeg, 2008.
ICD-10	H18.4
ICD-9	371.41
OMIM	107800
DiseasesDB	17120
MeSH	D001112

Arcus senilis (or arcus senilis corneae) is a white, gray, or blue opaque ring in the corneal margin (peripheral corneal opacity), or white ring in front of the periphery of the iris. It is present at birth, but then fades; however, it is quite commonly present in the elderly. It can also appear earlier in life as a result of hypercholesterolemia. Arcus senilis can be confused with the limbus sign, which reflects calcium rather than lipid deposits.

Alternative names

It is also called arcus adiposus, arcus juvenilis (when it occurs in younger individuals), arcus lipoides corneae or arcus cornealis; sometimes a gerontoxon.

Causes

It results from cholesterol deposits in or hyalinosis of the corneal stroma, and may be associated with ocular defects or with familial hyperlipidemia. It is common in the apparently healthy middle aged and elderly; a prospective cohort study of 12,745 Danes followed up for a mean of 22 years found that it had no clinical value as a predictor of cardiovascular disease.

It can be a sign of disturbance in lipid metabolism, an indicator of conditions such as hypercholesterolemia, hyperlipoproteinemia or hyperlipidemia.

Unilateral arcus is a sign of decreased blood flow to the unaffected eye, due to carotid artery disease or ocular hypotony.

People over the age of 60 may present with a ring-shaped, grayish-white deposit of phospholipid and cholesterol near the peripheral edge of the cornea.

Younger people with the same abnormality at the edge of the cornea would be termed arcus juvenilis.

References

External links

• Photo at kumc.edu
• Photo at hoppingeyeassociates.com
• Photo at apollolipids.org
• Definition at Merriam-Webster Medical Dictionary

UpToDate Contents

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English Journal

• Molecular-genetic aspects of familial hypercholesterolemia.

• Gabcova-Balaziova D, Stanikova D, Vohnout B, Huckova M, Stanik J, Klimes I, Raslova K, Gasperikova D.
• Endocrine regulations.Endocr Regul.2015 Jul;49(3):164-81.
• Familial hypercholesterolemia (FH) is the world's most abundant and the most common heritable disorder of lipid metabolism. The prevalence of the disease in general population is 1:500. Therefore the approximate number of FH patients all over the world is 14 million. From the genetic point of view t
• PMID 26238499

• [Familial hypercholesterolemia - past and present. My experiences and findings in our group of patients with familial hypercholesterolemia].

• Češka R, Vrablík M, Altschmiedová T, Prusíková M, Urbanová Z, Šobra J.
• Vnitr̆ní lékar̆ství.Vnitr Lek.2014 Nov;60(11):963-9.
• Currently, the familial hypercholesterolemia (FH) rises the interest. The reason is that this genetic disorder is targeted by newly emerged and highly effective hypolipidemic agents, PCSK-9 inhibitors, lomitapid and mipomersen. Present paper discusses 2 patient study groups, before 50 years and nowa
• PMID 25600043

• [The clinical manifestations of atherosclerosis in familial hypercholesterolemia].

• Korneva VA, Kyznetsova TIu, Mandel'shtam MIu, Konstantinov VO, Vasil'ev VB.
• Terapevticheskiĭ arkhiv.Ter Arkh.2014;86(1):18-22.
• AIM: To study the specific features of manifestations of atherosclerosis in Karelia dwellers with familial hypercholesterolemia (FH).SUBJECTS AND METHODS: The examination of 196 patients with FH involved laboratory tests, electrocardiography, echocardiography, triplex scanning of the arteries, exerc
• PMID 24754064

Related Links

• Arcus senilis – Wikipedia

Als Arcus senilis (corneae) (auch Arcus lipoides corneae, Greisenbogen oder Gerontoxon) wird ein durch Lipideinlagerung bedingter schmaler, vom Hornhautrand (Limbus) abgesetzter Trübungsring der bradytrophen Cornea des Auges ...

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「arc」

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