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1. 喘息の治験薬investigational agents for asthma [show details]
…therapy or experience adverse effects with conventional agents. Ongoing research is attempting to identify more effective and less toxic agents to control asthma. Investigational approaches to asthma …
2. 全身麻酔：静脈麻酔薬general anesthesia intravenous induction agents [show details]
…anesthetic agents acting on other receptor types due to synergistic effects. Adjuvant intravenous (IV) agents are often used to supplement the effects of the primary anesthetic induction agent. The most …
3. 化学療法剤の腸管毒性enterotoxicity of chemotherapeutic agents [show details]
…with this agent, diarrhea occurred in 51 percent of patients, with 8 percent of the events being grade 3 or 4. Diarrhea is less common and less severe with carfilzomib and the orally active agent ixazomib …
4. 吸入麻酔薬：臨床作用と臨床使用inhalation anesthetic agents clinical effects and uses [show details]
…(Stage I). All inhalation agents are associated with increased risk for postoperative nausea and vomiting (PONV) compared with IV anesthetic agents . Similar to opioid agents, inhalation anesthetics stimulate …
5. 喘息マネージメントでの抗ロイコトリエン薬の使用antileukotriene agents in the management of asthma [show details]
…antileukotriene agents are added to inhaled and/or oral glucocorticoids . Antileukotriene agents also improve the safety of aspirin desensitization. Exercise-induced symptoms – Antileukotriene agents are generally …

English Journal

Access to and price trends of antidiabetic, antihypertensive, and antilipidemic drugs in outpatient settings of the Universal Coverage Scheme in Thailand.

Limwattananon C, Waleekhachonloet O.
PloS one. 2019 ;14(2)e0211759.
Under the Universal Coverage Scheme (UCS) with payment per capita for outpatient (OP) services, hospitals' financial risks will rise if access to essential drugs increases. This study examined trends in access to and price of essential drugs for noncommunicable diseases (NCDs) and an overall purchas
PMID 30785916

Transitional changes in the incidence of osteonecrosis in systemic lupus erythematosus patients: focus on immunosuppressant agents and glucocorticoids.

Nawata K, Nakamura J, Ikeda K, Furuta S, Nakajima H, Ohtori S, Hagiwara S, Wako Y, Miura M, Kawarai Y, Sugano M, Yoshino K, Orita S, Inage K, Akazawa T.
Rheumatology (Oxford, England). 2018 05;57(5)844-849.
The purpose of this study was to investigate transitional changes in the incidence of glucocorticoid-associated osteonecrosis in SLE patients, with a focus on immunosuppressive agent and glucocorticoid consumption. We retrospectively registered 185 SLE patients with 740 joints, who were newly diagno
PMID 29462407

Phytochemical composition, antilipidemic and antihypercholestrolemic perspectives of Bael leaf extracts.

Asghar N, Mushtaq Z, Arshad MU, Imran M, Ahmad RS, Hussain SM.
Lipids in health and disease. 2018 Apr;17(1)68.
In recent times, focus on plant research has improved all over the world and essential parts of plants provide bioactive compounds in human diet. The bael (Aegle marmelos) has enormous traditional uses in the treatment of chronic diarrhea, dysentery, peptic ulcers and as a laxative. The main focus o
PMID 29615046

Japanese Journal

Do antilipidemic agents reduce blood pressure?

Oyama Jun-ichi,Uchida Fumi,Node Koichi
Vascular Failure 2(1), 6-10, 2018
… Although HT, DM, and HL are different diseases, they share some of the same pathophysiological mechanisms and ultimately lead to the same cardiovascular events.Currently, most patients with CVD are treated with 3-hydroxy-3-methyl-glutaryl-coenzyme A reductase inhibitors (statins), and various beneficial pleiotropic effects of statins have been reported since the 1990s.In this review, we evaluate the additional effects of antihyperlipidemic agents on blood pressure (BP). …
NAID 130007399357

頭頸部癌の手術中に脳梗塞を発症した2例

中村泰介,嶋根俊和,下鑪裕子,徳留卓俊,川口顕一朗,河村陽二郎,秋山理央,卯月彩,五味渕寛,三邉武幸
頭頸部癌 = Head and neck cancer 38(3), 380-384, 2012-10-25
高齢化社会となった現在，高齢者の頸動脈硬化および狭窄を有する症例に対し頭頸部手術を行うことは稀なことではなく，今後も増加していくと考えられる。今回我々は舌癌の頸部リンパ節転移に対する頸部郭清術，喉頭癌に対する喉頭全摘出術の手術中に発症した脳梗塞の2症例を経験した。いずれの症例も高齢者に対する手術であり，また術前の頸部CTにて高度の動脈硬化や頸動脈狭窄を認めており，脳梗塞の発症リスクは非常に高いと考 …
NAID 10031170541