UpToDate Contents

全文を閲覧するには購読必要です。 To read the full text you will need to subscribe.

1. ステロイドの全身投与の主な副作用 major side effects of systemic glucocorticoids
2. ステロイドの薬理学的使用 pharmacologic use of glucocorticoids
3. ステロイドの中断 glucocorticoid withdrawal
4. ステロイド誘発性骨粗鬆症の予防および治療 prevention and treatment of glucocorticoid induced osteoporosis
5. 敗血症性ショックへの糖質コルチコイド療法 glucocorticoid therapy in septic shock

English Journal

Wu J, Zheng C, Wang X, Yun S, Zhao Y, Liu L, Lu Y, Ye Y, Zhu X, Zhang C, Shi S, Liu Z.
The Journal of clinical investigation.J Clin Invest.2015 Nov 2;125(11):4091-106. doi: 10.1172/JCI81061. Epub 2015 Oct 5.
Calcium/calcineurin signaling is critical for normal cellular physiology. Abnormalities in this pathway cause many diseases, including podocytopathy; therefore, understanding the mechanisms that underlie the regulation of calcium/calcineurin signaling is essential. Here, we showed that critical comp
PMID 26436650

A Podocyte-Based Automated Screening Assay Identifies Protective Small Molecules.

Lee HW1, Khan SQ1, Faridi MH1, Wei C1, Tardi NJ1, Altintas MM1, Elshabrawy HA1, Mangos S1, Quick KL2, Sever S3, Reiser J4, Gupta V4.
Journal of the American Society of Nephrology : JASN.J Am Soc Nephrol.2015 Nov;26(11):2741-52. doi: 10.1681/ASN.2014090859. Epub 2015 Apr 9.
Podocyte injury and loss mark an early step in the pathogenesis of various glomerular diseases, making these cells excellent targets for therapeutics. However, cell-based high-throughput screening assays for the rational development of podocyte-directed therapeutics are currently lacking. Here, we d
PMID 25858967

Identification of Promising Urinary MicroRNA Biomarkers in Two Rat Models of Glomerular Injury.

Nassirpour R1, Homer BL2, Mathur S3, Li Y3, Li Z2, Brown T4, Carraher D2, Warneke J2, Bailey S2, Percival K2, O'Neil SP2, Whiteley LO2.
Toxicological sciences : an official journal of the Society of Toxicology.Toxicol Sci.2015 Nov;148(1):35-47. doi: 10.1093/toxsci/kfv167. Epub 2015 Aug 7.
MicroRNAs (miRNAs) are small, noncoding RNAs that regulate protein levels posttranscriptionally. miRNAs play important regulatory roles in many cellular processes and have been implicated in several diseases. Recent studies have reported significant levels of miRNAs in a variety of body fluids, rais
PMID 26253709

微小変化型ネフローゼ症候群の病態発症機序,診断マーカーの有用性についての検討 : ラットPuromycin aminonucleoside腎症における各種ポドサイト機能分子の発現解析

海外論文紹介 : The Immunosuppressive Drug Mizoribine Directly Prevents Podocyte Injury in Puromycin Aminonucleoside Nephrosis

Tolvaptan, a selective oral vasopressin V2 receptor antagonist, ameliorates podocyte injury in puromycin aminonucleoside nephrotic rats

OKADA Tadashi,SAKAGUCHI Toshifumi,HATAMURA Ikuji,SAJI Fumie,NEGI Shigeo,OTANI Haruhisa,MURAGAKI Yasuteru,KAWACHI Hiroshi,SHIGEMATSU Takashi
Clinical and experimental nephrology 13(5), 438-446, 2009-10-01
NAID 10027226471