actin stress fiber

• アクチンストレスファイバー、アクチンストレス線維

WordNet

1. something that people do or cause to happen (同)deed, human action, human_activity
2. behave in a certain manner; show a certain behavior; conduct or comport oneself; "You should act like an adult"; "Dont behave like a fool"; "What makes her do this way?"; "The dog acts ferocious, but he is really afraid of people" (同)behave, do
3. pretend to have certain qualities or state of mind; "He acted the idiot"; "She plays deaf when the news are bad" (同)play, act_as
4. a legal document codifying the result of deliberations of a committee or society or legislative body (同)enactment
5. a short theatrical performance that is part of a longer program; "he did his act three times every evening"; "she had a catchy little routine"; "it was one of the best numbers he ever did" (同)routine, number, turn, bit
6. a manifestation of insincerity; "he put on quite an act for her benefit"
7. a subdivision of a play or opera or ballet
8. discharge ones duties; "She acts as the chair"; "In what capacity are you acting?"
9. perform an action, or work out or perform (an action); "think before you act"; "We must move quickly"; "The governor should act on the new energy bill"; "The nanny acted quickly by grabbing the toddler and covering him with a wet towel" (同)move
10. play a role or part; "Gielgud played Hamlet"; "She wants to act Lady Macbeth, but she is too young for the role"; "She played the servant to her husbands master" (同)play, represent
11. perform on a stage or theater; "She acts in this play"; "He acted in `Julius Caesar"; "I played in `A Christmas Carol" (同)play, roleplay, playact
12. be engaged in an activity, often for no particular purpose other than pleasure
13. be suitable for theatrical performance; "This scene acts well"
14. to stress, single out as important; "Dr. Jones emphasizes exercise in addition to a change in diet" (同)emphasize, emphasise, punctuate, accent, accentuate
15. special emphasis attached to something; "the stress was more on accuracy than on speed" (同)focus
16. difficulty that causes worry or emotional tension; "she endured the stresses and strains of life"; "he presided over the economy during the period of the greatest stress and danger"- R.J.Samuelson (同)strain
17. (physics) force that produces strain on a physical body; "the intensity of stress is expressed in units of force divided by units of area"
18. the relative prominence of a syllable or musical note (especially with regard to stress or pitch); "he put the stress on the wrong syllable" (同)emphasis, accent
19. put stress on; utter with an accent; "In Farsi, you accent the last syllable of each word" (同)accent, accentuate
20. tell a relatively insignificant lie; "Fibbing is not acceptable, even if you dont call it lying"
21. a trivial lie; "he told a fib about eating his spinach"; "how can I stop my child from telling stories?" (同)story, tale, tarradiddle, taradiddle
22. a slender and greatly elongated substance capable of being spun into yarn (同)fibre
23. a leatherlike material made by compressing layers of paper or cloth (同)fibre, vulcanized fiber
24. any of several elongated, threadlike cells (especially a muscle fiber or a nerve fiber) (同)fibre
25. suffering severe physical strain or distress; "he dropped out of the race, clearly distressed and having difficulty breathing" (同)distressed
26. bearing a stress or accent; "an iambic foot consists of an unstressed syllable followed by a stressed syllable as in `delay" (同)accented

PrepTutorEJDIC

1. 『行い』,『行為』 / 《しばしばA-》法令,条令 / 《しばしばA-》(芝居の1つの)『幕』;(演芸などの)出し物の一つ / (見せかけの)お芝居,演技 / 『行動する』,行う / 《様態を表す副詞[句]を伴って》わざとふるまう,見せかける / 〈人・物が〉(…として)動く,役割をはたす《+『as』+『名』》 / 〈薬が〉『作用する』,きく / 舞台に立つ,出演する / 〈…の役〉'を'『演ずる』;〈劇〉'を'上演する / …‘に'ふさわしくふるまう / …‘に'見せかける,‘の'ふりをする
2. 〈U〉〈C〉(精神的・感情的な)『緊張』,ストレス / 〈U〉(…に対する)『強調』,力説《+on+名》 / 〈C〉〈U〉『強勢』,アクセント / 〈U〉(一般に)『圧迫』,圧力 / …‘を'『強調する』,力説する / 〈音節・語〉‘に'強勢(アクセント)を置く / 《まれ》（に）圧力をかける
3. (ささいな,罪のない)うそ / 軽いうそをつく

UpToDate Contents

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• 1. 糸球体足細胞のバイオロジー biology of glomerular podocytes
• 2. 先天性ミオパシー congenital myopathies
• 3. 拡張能障害の細胞学的機序 cellular mechanisms of diastolic dysfunction
• 4. 心不全の病態生理：左心室の圧-容積関係 pathophysiology of heart failure left ventricular pressure volume relationships
• 5. 運動生理学 exercise physiology

English Journal

• Fn14 promotes differentiation of human mesenchymal stem cells into heart valvular interstitial cells by phenotypic characterization.

• Huang W1, Xiao DZ, Wang Y, Shan ZX, Liu XY, Lin QX, Yang M, Zhuang J, Li Y, Yu XY.Author information 1Medical Research Center of Guangdong General Hospital, Guangdong Provincial Cardiovascular Institute, Guangdong Academy of Medical Sciences, Guangzhou, Guangdong, China.AbstractDespite the fact that tissue engineered heart valves (TEHV) hold great promise for heart valve disease treatment, one of the challenges is to find suitable seeding cells. Bone marrow derived mesenchymal stem cells (MSCs) were considered to be one of the best seed cell sources. In this study we propose a novel approach to promote stem cell differentiation into the seed cells of TEHV, valvular interstitial cells (VICs). Newly induced MSCs (iMSCs) were created from a co-culture niche in which healthy human donor derived MSCs were co-cultured with cardiac fibroblasts (H9C2 cell line). Then iMSCs were transfected with either a mock vector (iMSCs(mock) ) as controls or with a vector that overexpresses thefibroblast inducible factor 14 (Fn14) gene (iMSCs(Fn14) ). Immunofluorescence staining was performed to assay VIC differentiation. Western blot analysis was performed to analyze the involved signaling pathway. The results demonstrate that the expression of α-smooth muscle actin (SMA) was significantly higher in iMSCs(Fn14) as compared with iMSC(mock) , and MSC, and also had higher co-alignment of α-actinin and stress fiber (F-actin) in bundles. Additionally, increased biosynthesis of extracellular matrix (ECM) proteins including collagen I, collagen III, and fibronection were observed in iMSCs(Fn14) in comparison with iMSCs(mock) . These data observed in iMSCs(Fn14) were in accordance with VIC phenotype from normal heart valves. In addition, the PI3K/Akt signaling pathway was activated in iMSCs(Fn14) which allowed higher Akt phosphorylation (p-Akt) levels and SMA levels, whereas, it was attenuated by LY294002 (PI3K/Akt inhibitor). These new findings of the effect of Fn14 on VIC-like cell differentiation may provide a novel therapeutic strategy for heart valve disease treatment. J. Cell. Physiol. 229: 580-587, 2014. © 2013 Wiley Periodicals, Inc.
• Journal of cellular physiology.J Cell Physiol.2014 May;229(5):580-7. doi: 10.1002/jcp.24480.
• Despite the fact that tissue engineered heart valves (TEHV) hold great promise for heart valve disease treatment, one of the challenges is to find suitable seeding cells. Bone marrow derived mesenchymal stem cells (MSCs) were considered to be one of the best seed cell sources. In this study we propo
• PMID 24122208

• Physicochemical properties of surimi gels fortified with dietary fiber.

• Debusca A1, Tahergorabi R, Beamer SK, Matak KE, Jaczynski J.Author information 1West Virginia University, Division of Animal and Nutritional Sciences, P.O. Box 6108, Morgantown, WV 26506-6108, USA.AbstractAlthough dietary fiber provides health benefits, most Western populations have insufficient intake. Surimi seafood is not currently fortified with dietary fiber, nor have the effects of fiber fortification on physicochemical properties of surimi been thoroughly studied. In the present study, Alaska pollock surimi was fortified with 0-8 g/100 g of long-chain powdered cellulose as a source of dietary fiber. The protein/water concentrations in surimi were kept constant by adding an inert filler, silicon dioxide in inverse concentrations to the fiber fortification. Fiber-fortified surimi gels were set at 90 °C. The objectives were to determine (1) textural and colour properties; (2) heat-induced gelation (dynamic rheology); and (3) protein endothermic transitions (differential scanning calorimetry) of surimi formulated with constant protein/water, but variable fiber content. Fiber fortification up to 6 g/100 g improved (P<0.05) texture and colour although some decline occurred with 8 g/100g of fiber. Dynamic rheology correlated with texture and showed large increase in gel elasticity, indicating enhanced thermal gelation of surimi. Differential scanning calorimetry showed that fiber fortification did not interfere with thermal transitions of surimi myosin and actin. Long-chain fiber probably traps water physically, which is stabilized by chemical bonding with protein within surimi gel matrix. Based on the present study, it is suggested that the fiber-protein interaction is mediated by water and is physicochemical in nature.
• Food chemistry.Food Chem.2014 Apr 1;148:70-6. doi: 10.1016/j.foodchem.2013.10.010. Epub 2013 Oct 11.
• Although dietary fiber provides health benefits, most Western populations have insufficient intake. Surimi seafood is not currently fortified with dietary fiber, nor have the effects of fiber fortification on physicochemical properties of surimi been thoroughly studied. In the present study, Alaska
• PMID 24262528

• Regional-specific alterations in cell-cell junctions, cytoskeletal networks and myosin-mediated mechanical cues coordinate collectivity of movement of epithelial cells in response to injury.

• Menko AS1, Bleaken BM2, Walker JL3.Author information 1Department of Pathology, Anatomy and Cell Biology, Thomas Jefferson University, Philadelphia, PA 19107, United States; Wills Vision Research Center at Jefferson, Philadelphia, PA 19107, United States.2Department of Pathology, Anatomy and Cell Biology, Thomas Jefferson University, Philadelphia, PA 19107, United States.3Department of Pathology, Anatomy and Cell Biology, Thomas Jefferson University, Philadelphia, PA 19107, United States; Wills Vision Research Center at Jefferson, Philadelphia, PA 19107, United States. Electronic address: janice.l.walker@jefferson.edu.AbstractThis study investigates how epithelial cells moving together function to coordinate their collective movement to repair a wound. Using a lens ex vivo mock cataract surgery model we show that region-specific reorganization of cell-cell junctions, cytoskeletal networks and myosin function along apical and basal domains of an epithelium mediates the process of collective migration. An apical junctional complex composed of N-cadherin/ZO-1/myosin II linked to a cortical actin cytoskeleton network maintains integrity of the tissue during the healing process. These cells' basal domains often preceded their apical domains in the direction of movement, where an atypical N-cadherin/ZO-1 junction, linked to an actin stress fiber network rich in phosphomyosin, was prominent in cryptic lamellipodia. These junctions joined the protruding forward-moving lamellipodia to the back end of the cell moving directly in front of it. These were the only junctions detected in cryptic lamellipodia of lens epithelia migrating in response to wounding that could transmit the protrusive forces that drive collective movement. Both integrity of the epithelium and ability to effectively heal the wound was found to depend on myosin mechanical cues.
• Experimental cell research.Exp Cell Res.2014 Mar 10;322(1):133-48. doi: 10.1016/j.yexcr.2013.12.021. Epub 2014 Jan 4.
• This study investigates how epithelial cells moving together function to coordinate their collective movement to repair a wound. Using a lens ex vivo mock cataract surgery model we show that region-specific reorganization of cell-cell junctions, cytoskeletal networks and myosin function along apical
• PMID 24397950

Japanese Journal

• Cellular traction forces increase during consecutive mechanical stretching following traction force attenuation

• Journal of Biomechanical Science and Engineering 12(3), 17-00118-17-00118, 2017
• NAID 130005830376

• Cell migration guided by a groove with branches

• Journal of Biomechanical Science and Engineering 12(1), 16-00613-16-00613, 2017
• NAID 130005520029

• Cellular traction forces increase during consecutive mechanical stretching following traction force attenuation

• Journal of Biomechanical Science and Engineering, 2017
• NAID 130005437630

Related Links

• アクチン（actin） - GRADUATE SCHOOL OF BIOSTUDIES ...

アクチン（ actin ） すべての真核細胞に存在 その多くでもっとも大量に存在：全タンパク質の 5％、脊椎動物の骨格筋細胞では全重量の20％。 筋肉の乾燥粉末をうすい塩溶液で処理するとアクチンフィラメントからアクチンが ...

• CiNii 論文 - 微小管崩壊によるActin Stress Fiber形成の ...

微小管崩壊によるActin Stress Fiber形成のメカニズム(II) : チューブリン蛋白によるRhoGDI 活性の抑制 The formation of actin stress fiber formation by microtubule disruption 榎本 平 ENOMOTO Taira 神戸大・医 Med. Sch. 向井 秀幸 ...

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★リンクテーブル★

リンク元	「アクチンストレス線維」「アクチンストレスファイバー」
関連記事	「stress」「act」

「アクチンストレス線維」

　　[★]

英

actin stress fiber

関

アクチンストレスファイバー

「アクチンストレスファイバー」

　　[★]

英

actin stress fiber

関

アクチンストレス線維

「stress」

　　[★]

• n.

• ストレス、緊張、応力、力点

• v.

• 強調する

関

accent、accentuate、accentuation、emphasis、emphasize、highlight、power point、strain、tone、tonus、underscore

　 　 　 　 　 　 　

「act」

　　[★]

• v.

• 作用する、行動する、働く

• n.

• 行為、(法律)条例

関

action、behave、behavior、behavioral、behaviour、behavioural、conduct、effect、work