WordNet

German conductor and composer of romantic operas (1786-1826) (同)Carl Maria von Weber, Baron Karl Maria Friedrich Ernst von Weber
German physiologist who studied sensory responses to stimuli and is considered the father of psychophysics (1795-1878) (同)E. H. Weber, Ernst Heinrich Weber
German sociologist and pioneer of the analytic method in sociology (1864-1920) (同)Max Weber
United States abstract painter (born in Russia) (1881-1961) (同)Max Weber
German physicist and brother of E. H. Weber; noted for his studies of terrestrial magnetism (1804-1891) (同)Wilhelm Eduard Weber
a pattern of symptoms indicative of some disease
a complex of concurrent things; "every word has a syndrome of meanings"
a unit of magnetic flux equal to 100,000,000 maxwells (同)Wb

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(疾患の徴候となる一群の)症徴候,症候群 / (事件・社会的状態などのパターンを示す)徴候形態

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出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2017/08/26 23:35:49」(JST)

wiki en

Weber's syndrome (superior alternating hemiplegia) is a form of stroke characterized by the presence of an ipsilateral oculomotor nerve palsy and contralateral hemiparesis or hemiplegia.

Cause and presentation

This lesion is usually unilateral and affects several structures in the midbrain including:

Structure damaged	Effect
substantia nigra	contralateral parkinsonism because its dopaminergic projections to the basal ganglia innervate the ipsilateral hemisphere motor field, leading to a movement disorder of the contralateral body.
corticospinal fibers	contralateral hemiparesis and typical upper motor neuron findings. It is contralateral because it occurs before the decussation in the medulla.
corticobulbar tract	difficulty with contralateral lower facial muscles and hypoglossal nerve functions
oculomotor nerve fibers	ipsilateral oculomotor nerve palsy with a drooping eyelid and fixed wide pupil pointed down and out. This leads to diplopia

Human brainstem blood supply description. Posterior cerebral artery is #6, and midbrain is behind it.

It is caused by midbrain infarction as a result of occlusion of the paramedian branches of the posterior cerebral artery or of basilar bifurcation perforating arteries.^[1]

History

It carries the name of Sir Hermann David Weber, a German-born physician working in London, who described the condition in 1863.^[2]^[3] It is unrelated to Sturge-Weber syndrome, Klippel-Trenaunay-Weber syndrome or Osler-Weber-Rendu syndrome. These conditions are named for his son Frederick Parkes Weber.

References

^ "Weber's syndrome". GPnotebook.
^ Weber HD (1863). "A contribution to the pathology of the crura cerebri". Medico-Chirurgical Transactions. 46: 121–139.
^ Weber's syndrome at Who Named It?

External links

http://medinfo.ufl.edu/year2/neuro/review/bsc.html
http://www.neuropat.dote.hu/table/kereszt7.htm

UpToDate Contents

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1. 成人における第三脳神経（動眼神経）麻痺 third cranial nerve oculomotor nerve palsy in adults
2. スタージウェーバー症候群 sturge weber syndrome
3. クリッペル・トレノネー・ウェーバー症候群：臨床症状、診断、マネージメント klippel trenaunay syndrome clinical manifestations diagnosis and management
4. 食道輪および食道ウェブ esophageal rings and webs
5. 遺伝性出血性毛細血管拡張症（オースラー・ウェーバー・ランデュ症候群）の臨床症状と診断 clinical manifestations and diagnosis of hereditary hemorrhagic telangiectasia osler weber rendu syndrome

English Journal

Cell proliferation and oxidative stress pathways are modified in fibroblasts from Sturge-Weber syndrome patients.

Kadam SD, Gucek M, Cole RN, Watkins PA, Comi AM.SourceDepartments of Neurology and Developmental Medicine, Hugo Moser Kennedy Krieger Research Institute, Baltimore, USA.
Archives of dermatological research.Arch Dermatol Res.2012 Mar 10. [Epub ahead of print]
Sturge-Weber syndrome (SWS) is defined by vascular malformations of the face, eye and brain and an underlying somatic mutation has been hypothesized. We employed isobaric tags for relative and absolute quantification (iTRAQ-8plex)-based liquid chromatography interfaced with tandem mass spectrometry
PMID 22402795

Novel Regulators of Planar Cell Polarity: A Genetic Analysis in Drosophila.

Weber U, Gault WJ, Olguin P, Serysheva E, Mlodzik M.SourceMount Sinai School of Medicine.
Genetics.Genetics.2012 Mar 5. [Epub ahead of print]
Planar cell polarity (PCP) is a common feature of many epithelia and epithelial organs. Although progress has been made in the dissection of molecular mechanisms regulating PCP, many questions remain. Here we describe a screen to identify novel PCP regulators in Drosophila. We employed mild gain-of-
PMID 22391484

Japanese Journal

出血性ショックに至った肺動静脈奇形の1例

橋詰直樹,穴山貴嗣,久米基彦
日本呼吸器外科学会雑誌 = The journal of the Japanese Association for Chest Surgery 25(4), 406-412, 2011-05-15
症例は41歳女性．朝より呼吸困難，背部痛が出現したため近医受診．胸部造影CTにて左胸腔内出血，および左舌区末梢に径30mmの腫瘤を認めたため，肺動脈造影検査を施行したところ，A4，5を主体とするPulmonary Arteriovenous Malformation（以下PAVM）を認めた．カテーテルによる肺動脈塞栓術を試みたが，末梢の肺動脈に到達することが困難であり，時間経過とともに血胸が進行し …
NAID 10029125436

Rendu-Osler-Weber syndromeの出血性telangiectasiaをNBIで観察した一例

乾正幸,工藤智洋,星野崇,相馬宏光,長沼篤,高木均
The Kitakanto medical journal 61(2), 261-262, 2011-05-01
NAID 120003272638

「中脳」

Weber's syndrome
	Midbrain cross section showing lesion
Classification and external resources
ICD-10	G46.3
ICD-9-CM	344.89
DiseasesDB	31247
MeSH	D020526
	[edit on Wikidata]

　　[★]

英: midbrain
ラ: mesencephalon
関: 脳, 一次脳胞

解剖

中心管は、細い中脳水道となっている
中脳は３つの領域に分けられる。

中脳水道より背側にある領域は中脳蓋
腹外側に突出した部分は大脳脚
両者の間の領域が中脳被蓋である

発生

一次脳胞の中脳

脳神経の神経細胞

Henry Gray (1825-1861). Anatomy of the Human Body. 1918.

中脳とは(医学大事典)

間脳と橋および小脳の間に位置
第三脳室と第四脳室を連絡する中脳水道が正中面でやや背側を貫通
中脳水道の背側を中脳蓋、中脳水道の腹側が大脳脚

中脳蓋には上丘、下丘がある
上丘は上丘腕を介して、視床枕および外側膝状体と連絡
下丘は下丘腕を介して、内側膝状体と連絡

大脳脚はさらに２つに分けられ、背側の被蓋、腹側の狭義の大脳脚に分けられる。
被蓋と大脳脚の中間に黒質が存在する
被蓋：被蓋毛様体からなり、網膜核、動眼神経核、滑車神経核、三叉神経中脳路、内側縦束核、赤核、黒質からなる。
大脳脚：下行神経路があり、錐体路、頭頂橋路、側頭橋路、後頭橋路および前頭橋路が通る。

臨床関連

神経内科

ウェーバー症候群 Weber syndrome：一側の脳神経症状と反対側上下肢の運動麻痺が見られた場合、病変部は中脳であり、これをウェーバー症候群と呼ぶ。
ベネディクト症候群 Benedikt syndrome：障害部位は中脳の赤核であり、障害側と同側の動眼神経麻痺と、反対側の不随意運動を呈する。

「ウェーバー症候群」

　　[★]

英: Weber's syndrome, Weber syndrome
同: (国試)Weber症候群、上交代性片麻痺 superior alternating hemiplegia hemiplegia alternans superior、大脳脚症候群
関: 脳幹梗塞、Weber症候群、脳幹卒中、上交代性片麻痺、ウェーバー麻痺

一側の脳神経症状と反対側上下肢の運動麻痺が見られた場合、病変部は中脳であり、これをウェーバー症候群と呼ぶ。

「brainstem stroke」

　　[★]

脳幹卒中

関: brain stem infarction、brainstem infarction、Weber syndrome

「brainstem infarction」

　　[★]

脳幹梗塞

関: brain stem infarction、brainstem stroke、Weber syndrome

「brain stem infarction」

　　[★]

脳幹梗塞

関: brainstem infarction、brainstem stroke、Weber syndrome

「Klippel-Trenaunay-Weber syndrome」

　　[★] クリッペル・ウェーバー症候群

「Klippel-Weber syndrome」