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a pattern of symptoms indicative of some disease
a complex of concurrent things; "every word has a syndrome of meanings"
English industrialist who pioneered in the design and manufacture of aircraft (1885-1962) (同)Sir Frederick Handley Page
United States diplomat and writer about the Old South (1853-1922) (同)Thomas Nelson Page
English pathologist who discovered the cause of trichinosis (1814-1899) (同)Sir James Paget

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(疾患の徴候となる一群の)症徴候,症候群 / (事件・社会的状態などのパターンを示す)徴候形態

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出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2015/06/05 13:59:36」(JST)

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Paget–Schroetter disease, also known as Paget–von Schrötter disease, is a form of upper extremity deep vein thrombosis (DVT), a medical condition in which blood clots form in the deep veins of the arms. These DVTs typically occur in the axillary or subclavian veins.

Signs and symptoms

The condition is relatively rare.^[1] It usually presents in young and otherwise healthy patients, and also occurs more often in males than females. The syndrome also became known as "effort-induced thrombosis" in the 1960s,^[2] as it has been reported to occur after vigorous activity,^[3] though it can also occur spontaneously. It may develop as a sequela of thoracic outlet syndrome. Paget–Schroetter syndrome was described once for a viola player who suddenly increased practice time 10-fold, creating enough repetitive pressure against the brachiocephalic and external jugular veins to cause thrombosis.^[4]

Symptoms may include sudden onset of pain, warmth, redness, blueness and swelling in the arm. These DVTs rarely cause fatal pulmonary embolism.

Indexing deep vein thrombosis in ICD10 index book gives the code I80.2 which is specific to lower extremeties so the actual code should be I80.8 to clarifiy it is another site.

Treatment

The traditional treatment for thrombosis is the same as for a lower extremity DVT, and involves anticoagulation with heparin (generally low molecular weight heparin) with a transition to warfarin.

Alternative treatment is thrombolysis to open up the vein, which aims to reduce the incidence of post-thrombotic syndrome, followed by first-rib resection during the same hospital admission and not waiting for a repeat episode.

History

The condition is named after two men. James Paget^[5] first proposed the idea of venous thrombosis causing upper extremity pain and swelling,^[6] and Leopold von Schrötter later linked the clinical syndrome to thrombosis of the axillary and subclavian veins.^[7]

References

^ Hughes, ES (1949). "Venous obstruction in the upper extremity; Paget–Schroetter's syndrome; a review of 320 cases". Surg Gynecol Obstet 88 (2): 89–127. PMID 18108679.
^ Drapanas, T; Curran, WL (1966). "Thrombectomy in the treatment of "effort" thrombosis of the axillary and subclavian veins". Journal of Trauma (6): 107.
^ Flinterman LE; Van Der Meer FJ; Rosendaal FR; Doggen CJ (Aug 2008). "Current perspective of venous thrombosis in the upper extremity". Journal of Thrombosis and Haemostasis 6 (8): 1262–6. doi:10.1111/j.1538-7836.2008.03017.x. PMID 18485082.
^ Reina, Nick J.; Honet, Joseph C.; Brown, William; Beitman, Max; Chodoroff, Gary (1988). "Paget-Schroetter syndrome in a viola player". Medical Problems of Performing Artists 3 (1): 24.
^ Paget-von Schrötter disease at Who Named It?
^ Paget J (1866). "On gouty and some other forms of phlebitis". St. Bartholomew's Hospital Reports 2: 82–92.
^ L. von Schrötter. Erkrankungen der Gefässe. Nothnagel’s Handbuch der speciellen Pathologie und Therapie, 1901. Volume XV, II. Theil, II. Hälfte: Erkrankungen der Venen. Wien, Hölder, 1899: 533–535.

External links

Overview at Uniformed Services University of the Health Sciences
An image and case description from the NEJM

UpToDate Contents

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1. 原発性（特発性）上肢深部静脈血栓症 primary spontaneous upper extremity deep vein thrombosis
2. 静脈血栓症の原因の概要 overview of the causes of venous thrombosis
3. 胸郭出口症候群の概要 overview of thoracic outlet syndromes
4. 投擲による上肢の傷害：臨床症状および診断的アプローチ throwing injuries of the upper extremity clinical presentation and diagnostic approach
5. カテーテル関連の上肢静脈血栓症 catheter related upper extremity venous thrombosis

English Journal

Percutaneous Re-positioning of Dislocated Port-Catheters in Patients with Dysfunctional Central-Vein Port-Systems.

Massmann A1, Jagoda P2, Kranzhoefer N3, Buecker A2.
Annals of surgical oncology.Ann Surg Oncol.2015 Dec;22(13):4124-9. doi: 10.1245/s10434-015-4549-5. Epub 2015 Apr 9.
PURPOSE: Observational analysis of percutaneous repositioning of displaced port-catheters in patients with dysfunctional central-venous port-systems.METHODS: A total of 1061 patients with dysfunctional venous pectoral port-systems were referred for port-angiography. Dislocated port-catheters were id
PMID 25854845

Paget-Schroetter syndrome: A review and Algorithm (WASPS-IR).

Naeem M1, Soares G2, Ahn S1, Murphy TP1.
Phlebology / Venous Forum of the Royal Society of Medicine.Phlebology.2015 Dec;30(10):675-86. doi: 10.1177/0268355514568534. Epub 2015 Feb 11.
Venous compression syndromes are rare and occur due to the entrapment of vein(s) in confined anatomical spaces bounded by osseous and non-osseous structures. Here we present a review of Paget-Schroetter Syndrome, an important cause of upper extremity of deep vein thrombosis, its associated clinical
PMID 25673095

Japanese Journal

Differential diagnosis of a rare case of upper limb pain: Paget-Schroetter syndrome in a doner kebab chef

Journal of Physical Therapy Science 27(10), 3333-3335, 2015
NAID 130005105971

Acute Pulmonary Embolism due to Paget-Schroetter Syndrome

Internal Medicine 54(15), 1875-1879, 2015
NAID 130005090917

Related Pictures

★リンクテーブル★

リンク元	「パジェット・シュレッター症候群」
関連記事	「syndrome」

「パジェット・シュレッター症候群」

Paget-Schrotter disease
	Anterior view of right upper limb and thorax
Classification and external resources
ICD-10	I82.8
ICD-9	453.8
DiseasesDB	34349
eMedicine	med/2772

　　[★]

英: Paget-Schroetter syndrome
同: 労作性血栓症 effort thrombosis

「syndrome」

　　[★]

n.

症候群

[1] Hughes, ES (1949). "Venous obstruction in the upper extremity; Paget–Schroetter's syndrome; a review of 320 cases". Surg Gynecol Obstet 88 (2): 89–127. PMID 18108679.

[2] Drapanas, T; Curran, WL (1966). "Thrombectomy in the treatment of "effort" thrombosis of the axillary and subclavian veins". Journal of Trauma (6): 107.

[3] Flinterman LE; Van Der Meer FJ; Rosendaal FR; Doggen CJ (Aug 2008). "Current perspective of venous thrombosis in the upper extremity". Journal of Thrombosis and Haemostasis 6 (8): 1262–6. doi:10.1111/j.1538-7836.2008.03017.x. PMID 18485082.

[4] Reina, Nick J.; Honet, Joseph C.; Brown, William; Beitman, Max; Chodoroff, Gary (1988). "Paget-Schroetter syndrome in a viola player". Medical Problems of Performing Artists 3 (1): 24.

[WhoNam-5] Paget-von Schrötter disease at Who Named It?

[Paget-6] Paget J (1866). "On gouty and some other forms of phlebitis". St. Bartholomew's Hospital Reports 2: 82–92.

[vonSch-7] L. von Schrötter. Erkrankungen der Gefässe. Nothnagel’s Handbuch der speciellen Pathologie und Therapie, 1901. Volume XV, II. Theil, II. Hälfte: Erkrankungen der Venen. Wien, Hölder, 1899: 533–535.

匿名

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案内

案内

Paget-Schroetter syndrome