WordNet
- a pattern of symptoms indicative of some disease
- a complex of concurrent things; "every word has a syndrome of meanings"
PrepTutorEJDIC
- (疾患の徴候となる一群の)症徴候,症候群 / (事件・社会的状態などのパターンを示す)徴候形態
Wikipedia preview
出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2016/02/07 14:27:29」(JST)
[Wiki en表示]
| Melkersson–Rosenthal syndrome |
| Classification and external resources |
| Specialty |
neurology |
| ICD-10 |
G51.2 |
| ICD-9-CM |
351.8 |
| OMIM |
155900 |
| DiseasesDB |
31963 |
| eMedicine |
derm/72 |
| MeSH |
D008556 |
|
[edit on Wikidata]
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Melkersson–Rosenthal syndrome (also termed "Miescher-Melkersson-Rosenthal syndrome"),[1] is a rare neurological disorder characterized by recurring facial paralysis, swelling of the face and lips (usually the upper lip), and the development of folds and furrows in the tongue.[2]:799 Onset is in childhood or early adolescence. After recurrent attacks (ranging from days to years in between), swelling may persist and increase, eventually becoming permanent. The lip may become hard, cracked, and fissured with a reddish-brown discoloration. The cause of Melkersson–Rosenthal syndrome is unknown, but there may be a genetic predisposition. It has been noted to be especially prevalent among certain ethnic groups in Bolivia. It can be symptomatic of Crohn's disease or sarcoidosis.[citation needed]
Contents
- 1 Treatment
- 2 Prognosis
- 3 Eponym
- 4 Research
- 5 See also
- 6 References
Treatment
Treatment is symptomatic and may include nonsteroidal anti-inflammatory drugs (NSAIDs) and corticosteroids to reduce swelling, antibiotics and immunosuppressants. Surgery may be indicated to relieve pressure on the facial nerves and reduce swelling, but its efficacy is uncertain. Massage and electrical stimulation may also be prescribed.[citation needed]
Prognosis
Melkersson–Rosenthal syndrome may recur intermittently after its first appearance. It can become a chronic disorder. Follow-up care should exclude the development of Crohn's disease or sarcoidosis.[citation needed]
Eponym
The condition is named for Ernst Melkersson and Curt Rosenthal.[3][4][5]
Research
The NINDS supports research on neurological disorders such as Melkersson–Rosenthal syndrome. Much of this research is aimed at increasing knowledge of these disorders and finding ways to treat, prevent, and ultimately cure them.
See also
- List of cutaneous conditions
References
- ^ http://www.dermnetnz.org/site-age-specific/granulomatous-cheilitis.html.
- ^ James, William D.; Berger, Timothy G.; et al. (2006). Andrews' Diseases of the Skin: Clinical Dermatology. Saunders Elsevier. ISBN 0-7216-2921-0.
- ^ synd/9 at Who Named It?
- ^ Melkersson, E. (1928). "Ett fall av recidiverande facialispares i samband med ett angioneurotiskt ödem". Hygiea (Stockholm) 90: 737–741.
- ^ Rosenthal, C. (1931). "Klinisch-erbbiologischer Beitrag zur Konstitutionspathologie. Gemeinsames Auftreten von Facialislähmung, angioneurotischem Gesichtsödem und Lingua plicata in Arthritismus-Familien". Zeitschrift für die gesamte Neurologie und Psychiatrie 131: 475–501. doi:10.1007/bf02865984.
- The original version of this article was taken from the public domain source at Melkersson–Rosenthal syndrome at nih.gov
|
Nervous system pathology, PNS, somatic (G50–G64, 350–357)
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|
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Nerve, nerve root, plexus
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Cranial nerve
disease |
- V Trigeminal neuralgia
- Anesthesia dolorosa
- VII Facial nerve paralysis
- Bell's palsy
- Melkersson–Rosenthal syndrome
- Parry–Romberg syndrome
- Central seven
- XI Accessory nerve disorder
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Radiculopathy,
plexopathy |
- brachial plexus Brachial plexus lesion
- Thoracic outlet syndrome
- Phantom limb
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Mono-
neuropathy |
| Upper limb |
| median nerve: |
- Carpal tunnel syndrome
- Ape hand deformity
|
|
| ulnar nerve: |
- Ulnar nerve entrapment
- Froment's sign
- Guyon's canal syndrome
- Ulnar claw
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| radial nerve: |
- Radial neuropathy
- Wrist drop
- Cheiralgia paresthetica
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| long thoracic nerve: |
- Winged scapula
- Backpack palsy
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| Lower limb |
| lateral cutaneous nerve of thigh: |
|
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| tibial nerve: |
|
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| plantar nerve: |
|
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| superior gluteal nerve: |
|
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| sciatic nerve: |
|
|
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| General |
- Causalgia
- Mononeuritis multiplex
- Neuropathy Neuralgia/Neuritis
- Nerve compression syndrome
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Polyneuropathies/Polyradiculoneuropathy
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|
| HMSN |
- Charcot–Marie–Tooth disease
- Dejerine–Sottas disease
- Refsum's disease
- Hereditary spastic paraplegia
- Hereditary neuropathy with liability to pressure palsy
- Familial amyloid neuropathy
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| Autoimmune/demyelinating |
- Guillain–Barré syndrome
- Chronic inflammatory demyelinating polyneuropathy
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| Other |
|
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Index of the peripheral nervous system
|
|
| Description |
- Anatomy
- Nerves
- cranial
- trigeminal
- cervical
- brachial
- lumbosacral plexus
- somatosensory
- spinal
- autonomic
- Physiology
- reflexes
- proteins
- neurotransmitters
- transporters
- Development
|
|
| Disease |
- Autonomic
- Congenital
- Injury
- Neoplasms and cancer
- Other
- Symptoms and signs
|
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| Treatment |
- Procedures
- Local anesthetics
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Oral and maxillofacial pathology (K00–K06, K11–K14, 520–525, 527–529)
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Lips
|
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- Cheilitis
- Actinic
- Angular
- Plasma cell
- Cleft lip
- Congenital lip pit
- Eclabium
- Herpes labialis
- Macrocheilia
- Microcheilia
- Nasolabial cyst
- Sun poisoning
- Trumpeter's wart
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|
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Tongue
|
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- Ankyloglossia
- Black hairy tongue
- Caviar tongue
- Crenated tongue
- Cunnilingus tongue
- Fissured tongue
- Foliate papillitis
- Glossitis
- Geographic tongue
- Median rhomboid glossitis
- Transient lingual papillitis
- Glossoptosis
- Hypoglossia
- Lingual thyroid
- Macroglossia
- Microglossia
- Rhabdomyoma
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|
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Palate
|
|
- Bednar's aphthae
- Cleft palate
- High-arched palate
- Palatal cysts of the newborn
- Inflammatory papillary hyperplasia
- Stomatitis nicotina
- Torus palatinus
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|
|
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Oral mucosa - Lining of mouth
|
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- Amalgam tattoo
- Angina bullosa haemorrhagica
- Behçet syndrome
- Bohn's nodules
- Burning mouth syndrome
- Candidiasis
- Condyloma acuminatum
- Darier's disease
- Epulis fissuratum
- Erythema multiforme
- Erythroplakia
- Fibroma
- Focal epithelial hyperplasia
- Fordyce spots
- Hairy leukoplakia
- Hand, foot and mouth disease
- Hereditary benign intraepithelial dyskeratosis
- Herpangina
- Herpes zoster
- Intraoral dental sinus
- Leukoedema
- Leukoplakia
- Lichen planus
- Linea alba
- Lupus erythematosus
- Melanocytic nevus
- Melanocytic oral lesion
- Molluscum contagiosum
- Morsicatio buccarum
- Oral cancer
- Benign: Squamous cell papilloma
- Keratoacanthoma
- Malignant: Adenosquamous carcinoma
- Basaloid squamous carcinoma
- Mucosal melanoma
- Spindle cell carcinoma
- Squamous cell carcinoma
- Verrucous carcinoma
- Oral florid papillomatosis
- Oral melanosis
- Pemphigoid
- Pemphigus
- Plasmoacanthoma
- Stomatitis
- Aphthous
- Denture-related
- Herpetic
- Smokeless tobacco keratosis
- Submucous fibrosis
- Ulceration
- Verruca vulgaris
- Verruciform xanthoma
- White sponge nevus
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Teeth (pulp, dentin, enamel)
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- Amelogenesis imperfecta
- Ankylosis
- Anodontia
- Caries
- Concrescence
- Delayed eruption
- Dens evaginatus
- Dentin dysplasia
- Dentin hypersensitivity
- Dentinogenesis imperfecta
- Dilaceration
- Discoloration
- Ectopic enamel
- Enamel hypocalcification
- Enamel hypoplasia
- Enamel pearl
- Fluorosis
- Fusion
- Gemination
- Hyperdontia
- Hypodontia
- Maxillary lateral incisor agenesis
- Impaction
- Macrodontia
- Meth mouth
- Microdontia
- Odontogenic tumors
- Keratocystic odontogenic tumour
- Odontoma
- Open contact
- Premature eruption
- Pulp calcification
- Pulp canal obliteration
- Pulp necrosis
- Pulp polyp
- Pulpitis
- Regional odontodysplasia
- Resorption
- Shovel-shaped incisors
- Supernumerary root
- Taurodontism
- Trauma
- Avulsion
- Cracked tooth syndrome
- Vertical root fracture
- Occlusal
- Tooth loss
- Tooth wear
- Abrasion
- Abfraction
- Acid erosion
- Attrition
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Periodontium (gingiva, Periodontal ligament, cementum, alveolus) - Gums and tooth-supporting structures
|
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- Cementicle
- Cementoblastoma
- Cementoma
- Eruption cyst
- Epulis
- Pyogenic granuloma
- Congenital epulis
- Gingival enlargement
- Gingival cyst of the adult
- Gingival cyst of the newborn
- Gingivitis
- Desquamative
- Granulomatous
- Plasma cell
- Hereditary gingival fibromatosis
- Hypercementosis
- Hypocementosis
- Linear gingival erythema
- Necrotizing periodontal diseases
- Acute necrotizing ulcerative gingivitis
- Pericoronitis
- Peri-implantitis
- Periodontal abscess
- Periodontal trauma
- Periodontitis
- Aggressive
- As a manifestation of systemic disease
- Chronic
- Perio-endo lesion
- Teething
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Periapaical, mandibular and maxillary hard tissues - Bones of jaws
|
|
- Agnathia
- Alveolar osteitis
- Buccal exostosis
- Cherubism
- Idiopathic osteosclerosis
- Mandibular fracture
- Microgenia
- Micrognathia
- Intraosseous cysts
- Odontogenic: periapical
- Dentigerous
- Buccal bifurcation
- Lateral periodontal
- Globulomaxillary
- Calcifying odontogenic
- Glandular odontogenic
- Non-odontogenic: Nasopalatine duct
- Median mandibular
- Median palatal
- Traumatic bone
- Osteoma
- Osteomyelitis
- Osteonecrosis
- Bisphosphonate-associated
- Neuralgia-inducing cavitational osteonecrosis
- Osteoradionecrosis
- Osteoporotic bone marrow defect
- Paget's disease of bone
- Periapical abscess
- Periapical periodontitis
- Stafne defect
- Torus mandibularis
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Temporomandibular joints, muscles of mastication and malocclusions - Jaw joints, chewing muscles and bite abnormalities
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- Bruxism
- Condylar resorption
- Mandibular dislocation
- Malocclusion
- Crossbite
- Open bite
- Overbite
- Overjet
- Prognathia
- Retrognathia
- Temporomandibular joint dysfunction
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Salivary glands
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- Benign lymphoepithelial lesion
- Ectopic salivary gland tissue
- Frey's syndrome
- HIV salivary gland disease
- Necrotizing sialometaplasia
- Mucocele
- Pneumoparotitis
- Salivary duct stricture
- Salivary gland aplasia
- Salivary gland atresia
- Salivary gland diverticulum
- Salivary gland fistula
- Salivary gland hyperplasia
- Salivary gland hypoplasia
- Salivary gland neoplasms
- Benign: Basal cell adenoma
- Canalicular adenoma
- Ductal papilloma
- Monomorphic adenoma
- Myoepithelioma
- Oncocytoma
- Papillary cystadenoma lymphomatosum
- Pleomorphic adenoma
- Sebaceous adenoma
- Malignant: Acinic cell carcinoma
- Adenocarcinoma
- Adenoid cystic carcinoma
- Carcinoma ex pleomorphic adenoma
- Lymphoma
- Mucoepidermoid carcinoma
- Sclerosing polycystic adenosis
- Sialadenitis
- Parotitis
- Chronic sclerosing sialadenitis
- Sialectasis
- Sialocele
- Sialodochitis
- Sialosis
- Sialolithiasis
- Sjögren's syndrome
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Orofacial soft tissues - Soft tissues around the mouth
|
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- Actinomycosis
- Angioedema
- Basal cell carcinoma
- Cutaneous sinus of dental origin
- Cystic hygroma
- Gnathophyma
- Ludwig's angina
- Macrostomia
- Melkersson–Rosenthal syndrome
- Microstomia
- Noma
- Oral Crohn's disease
- Orofacial granulomatosis
- Perioral dermatitis
- Pyostomatitis vegetans
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Other
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- Eagle syndrome
- Hemifacial hypertrophy
- Facial hemiatrophy
- Oral manifestations of systemic disease
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Index of the mouth
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| Description |
|
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| Disease |
- Congenital
- face and neck
- cleft
- digestive system
- Neoplasms and cancer
- Other
- Symptoms and signs
|
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| Treatment |
|
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UpToDate Contents
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English Journal
- Melkersson-Rosenthal syndrome: a retrospective study of 44 patients.
- Feng S1, Yin J, Li J, Song Z, Zhao G.
- Acta oto-laryngologica.Acta Otolaryngol.2014 Sep;134(9):977-81. doi: 10.3109/00016489.2014.927587. Epub 2014 Jun 25.
- CONCLUSION: When patients with recurrent facial paralysis are encountered, otolaryngologists should check for fissured tongue, and question those patients about orofacial edema, minor symptoms, and family history. Histologic evidence is not necessary for the diagnosis of Melkersson-Rosenthal syndrom
- PMID 24963969
- Tufted hair folliculitis associated with Melkersson-Rosenthal syndrome and hidradenitis suppurativa.
- Güngör S1, Yüksel T, Topal I.
- Indian journal of dermatology, venereology and leprology.Indian J Dermatol Venereol Leprol.2014 Sep-Oct;80(5):484. doi: 10.4103/0378-6323.140354.
- PMID 25201871
- Facial Palsy in Melkersson-Rosenthal Syndrome and Bell's Palsy: Familial History and Recurrence Tendency.
- Sun B1, Zhou C2, Han Z1.
- The Annals of otology, rhinology, and laryngology.Ann Otol Rhinol Laryngol.2014 Aug 13. pii: 0003489414546398. [Epub ahead of print]
- OBJECTIVE: The aim of this study was to compare genetic predilection and recurrence tendency between facial palsy in Melkersson-Rosenthal syndrome (MRS) and Bell's palsy METHODS: We carried out an investigation on patients with facial palsy in MRS and those with Bell's palsy who visited the outpatie
- PMID 25124841
Japanese Journal
- 症例報告 Melkersson-Rosenthal症候群の1例
- 症例報告 抜歯とトラニラスト内服が有効であったMelkersson-Rosenthal症候群の1例
Related Links
- General Discussion Melkersson Rosenthal syndrome is a rare neurological disorder characterized by recurrent, long lasting swelling of the face, particularly one or both lips (granulomatous cheilitis), facial muscle weakness (palsy ...
- Melkersson-Rosenthal syndrome is a rare neurological disorder characterized by recurring facial paralysis, swelling of the face and lips (usually the upper lip), and the development of folds and furrows in the tongue. Onset ...
- Sir, Melkersson–Rosenthal syndrome (MRS) is a very rare clinical entity. Its classical form is being characterized by following triad: Facial nerve palsy, swelling of lips, and fissured tongue.[] However, the ...
Related Pictures
★リンクテーブル★
[★]
- 英
- Melkersson-Rosenthal syndrome
- 同
- Melkersson-Rosenthal症候群、メルカーソン症候群 Melkersson syndrome
- 関
- 肉芽腫性口唇炎
[show details]
[★]
ローゼンタール症候群、Rosenthal症候群
- 関
- factor XI deficiency、hemophilia C
[★]