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1. 転移性乳癌へのアプローチの概要overview of the approach to metastatic breast cancer [show details]
… in sequence. Combination chemotherapy (rather than single-agent, sequential therapy) is most appropriate when the higher chance of response is assessed to be more important than the potential for higher …
2. 限局型小細胞肺癌：初期マネージメントlimited stage small cell lung cancer initial management [show details]
… followed sequentially by thoracic RT. Subsequent studies used EP in a similar sequential approach and demonstrated favorable response and survival rates with relatively tolerable toxicity . These regimens were …
3. 原発性（本態性）高血圧における薬物療法の選択choice of drug therapy in primary essential hypertension [show details]
… There are no strict guidelines as to how to perform sequential monotherapy, although the following approach is reasonable: The blood pressure response to initial monotherapy should be assessed in four to …
4. 転移性大腸癌に対する全身化学療法：一般原則systemic chemotherapy for metastatic colorectal cancer general principles [show details]
… potentially resectable after an initial chemotherapy response . Given the lack of a demonstrable survival benefit from multiagent chemotherapy, the use of sequential single agents might represent a reasonable alternative …
5. 原発性高シュウ酸尿症primary hyperoxaluria [show details]
… We then assess the response to therapy by comparing the 24-hour urine oxalate excretion before and after treatment. A positive response is defined as a reduction… There are four possible transplantation options: Combined liver and kidney transplantation; Sequential liver and kidney transplantation; Isolated liver transplantation;…