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1. 多系統萎縮症：臨床的特徴および診断multiple system atrophy clinical features and diagnosis [show details]
… nervous system suggests that MSA is a primary disorder of the glia . The glial (oligodendroglial) cytoplasmic inclusions that are characteristic of MSA contain hyperphosphorylated alpha-synuclein,… characteristic motor or autonomic features . However, the neuropathologic changes probably begin several years before the disease becomes symptomatic. The motor presentations of MSA…
2. 腫瘍壊死因子α（TNF-α）阻害剤：副作用の概要tumor necrosis factor alpha inhibitors an overview of adverse effects [show details]
… patient white blood cell count is stable. TNF-alpha is an important component of the immune system response to a variety of infections, and use of TNF-alpha inhibitors has been associated with an increased …
3. 多系統萎縮症：予後および治療multiple system atrophy prognosis and treatment [show details]
… an epitope similar to alpha-synuclein , and NCT02008721 , a phase III study investigating a putative neuroprotective agent that inhibits alpha-synuclein protein aggregation… Multiple system atrophy (MSA) is a unifying term that brings together a group of neurodegenerative disorders (olivopontocerebellar atrophy,… The motor symptoms in MSA are highly resistant to pharmacologic treatment.…
4. 胃排出遅延の原因pathogenesis of delayed gastric emptying [show details]
… of normal gastric motor function. The motor function of the gut is controlled at three main levels : Parasympathetic and sympathetic nervous systems; Enteric neurons… such as clonidine (alpha-2 adrenergic agonist), acotiamide (acetylcholinesterase inhibitor), or buspirone (5-HT1A agonist) . As previously mentioned, antral motor function is critical…
5. ポリオ後症候群post polio syndrome [show details]
… to explain the progression of motor neuron degeneration . Poliovirus and other enteroviruses can persist in the central nervous system as well as systemically in… cerebrospinal fluid (tumor necrosis factor alpha and interferon gamma) and serum (tumor necrosis factor alpha,…

Japanese Journal

α系亢進とγ系亢進とを分離して評価できるペンドラムテストモデル

軸屋和明,横平徳美,岡本卓爾,明石謙
電子情報通信学会技術研究報告. MBE, MEとバイオサイバネティックス 98(174), 7-14, 1998-07-14
… 筆者らのペンドラムテストモデル(PTM)は脊髄の機能を備え、その入力は上位からα運動細胞に至る基準化した刺激の頻度Fe、上位からシナプス前抑制に至る基準化した刺激の頻度Fiおよび上位からγ運動細胞に至る基準化した刺激の頻度Fγである。 …
NAID 110003287497

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