adj.

having a normal immune response
免疫適格性の？、免疫担当性の？

graft-versus-host disease is a feared complication of transplants of immunocompetent tissues from nonidentical donors.

The performance of a head CT scan before lumbar puncture is controversial but is generally not required ofr nonelderly, immunocompetent patients who present without focal neurologic abnormalities, seisures, or diminished level of consciousness.(WMM.371)

ex.

immunocompetent individual 免疫が保たれている人、immunocompetent organ 免疫担当組織、immunocompetent subject 免疫正常者

⇔compromised patient 易感染性患者、immune-compromised patient 免疫低下患者

WordNet

capable of developing an immune response following exposure to an antigen; "immunocompetent cells"
properly or sufficiently qualified or capable or efficient; "a competent typist"
adequate for the purpose; "a competent performance"
legally qualified or sufficient; "a competent court"; "competent testimony"
the ability to develop an immune response following exposure to an antigen

PrepTutorEJDIC

『有能な』,能力ある;適任の / (要求を満たすのに)十分な,満足できる / (役所・役人・証人などが)権限(資格)を持つ

Wikipedia preview

出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2014/07/17 05:19:02」(JST)

wiki en

[Wiki en表示]

Immunocompetence is the ability of the body to produce a normal immune response following exposure to an antigen. Immunocompetence is the opposite of immunodeficiency or immuno-incompetent or immuno-compromised. Examples include:

a newborn who does not yet have a fully functioning immune system but may have maternally transmitted antibodies - immunodeficient;
a late stage AIDS patient with a failed or failing immune system - immuno-incompetent; or
a transplant recipient taking medication so their body will not reject the donated organ - immunocompromised.

There may be cases of overlap but these terms are all indicators of non fully functioning immune system.

The US Centers for Disease Control and Prevention (CDC) recommends that household and other close contacts of persons with altered immunocompetence receive the MMR, varicella, and rotavirus vaccines according to the standard schedule of vaccines, as well as receiving an annual flu shot. All other vaccines may be administered to contacts without alteration to the vaccine schedule, with the exception of the smallpox vaccine. Persons with altered immunocompetence should not receive live, attenuated vaccines (viral or bacterial), and may not receive the full benefit of inactivated vaccines.^[1]

In reference to lymphocytes, immunocompetence means that a B cell or T cell is mature and can recognize antigens and allow a person to mount an immune response.

References

^ National Center for Immunization and Respiratory, Diseases (Jan 28, 2011). "General recommendations on immunization - recommendations of the Advisory Committee on Immunization Practices (ACIP).". MMWR. Recommendations and reports : Morbidity and mortality weekly report. Recommendations and reports / Centers for Disease Control 60 (2): 1–64. PMID 21293327.

UpToDate Contents

全文を閲覧するには購読必要です。 To read the full text you will need to subscribe.

1. 免疫宿主におけるトキソプラズマ症 toxoplasmosis in immunocompetent hosts
2. 免疫正常宿主におけるサイトメガロウイルス感染の疫学、臨床症状、および治療 epidemiology clinical manifestations and treatment of cytomegalovirus infection in immunocompetent hosts
3. 免疫能の正常な患者における発熱および発疹 fever and rash in the immunocompetent patient
4. 免疫正常患者における単純ヘルペスウイルス1型感染の治療 treatment of herpes simplex virus type 1 infection in immunocompetent patients
5. トキソプラズマ感染に対する診断的評価 diagnostic assays for toxoplasmosis infection

English Journal

18β-glycyrrhetinic acid inhibits hepatocellular carcinoma development by reversing hepatic stellate cell-mediated immunosuppression in mice.

Kuang P, Zhao W, Su W, Zhang Z, Zhang L, Liu J, Ren G, Yin Z, Wang X.SourceDepartment of Hepatobiliary Surgery, Zhongshan Hospital, Xiamen University, Xiamen, Fujian, China; Research Institute of Digestive Disease, Xiamen University, Xiamen, Fujian, China.
International journal of cancer. Journal international du cancer.Int J Cancer.2013 Apr 15;132(8):1831-41. doi: 10.1002/ijc.27852. Epub 2012 Oct 20.
Hepatic stellate cells (HSCs) have immunosuppressive capabilities and contribute to the occurrence and development of hepatocellular carcinoma (HCC). Thus, activated HSCs may be a suitable target for HCC therapy. Our study used mixed leukocyte reactions (MLR) in vitro to demonstrate that 18β-glycyr
PMID 22991231

Telomerase-specific oncolytic adenoviral therapy for orthotopic hepatocellular carcinoma in HBx transgenic mice.

Lin WH, Yeh SH, Yang WJ, Yeh KH, Fujiwara T, Nii A, Chang SS, Chen PJ.SourceDepartment of Microbiology, National Taiwan University College of Medicine, Taipei, Taiwan.
International journal of cancer. Journal international du cancer.Int J Cancer.2013 Mar 15;132(6):1451-62. doi: 10.1002/ijc.27770. Epub 2012 Nov 23.
The telomerase-specific replication-competent oncolytic adenovirus, Telomelysin, was developed for virus-mediated preferential lysis of tumor cells. Its selectivity is derived from a human telomerase reverse transcriptase (hTERT) promoter-driven active viral replication, which occurs in cancer cells
PMID 22886913

Cell phenotypic change due to Cryptosporidium parvum infection in immunocompetent mice.

Codices V, Martins C, Novo C, Pinho M, de Sousa B, Lopes A, Borrego M, Matos O.SourceUnidade de Parasitologia Médica, Grupo de Protozoários Oportunistas/VIH e Outros Protozoários, CMDT, Instituto de Higiene e Medicina Tropical, Universidade Nova de Lisboa, Lisboa, Portugal.
Acta parasitologica / Witold Stefański Institute of Parasitology, Warszawa, Poland.Acta Parasitol.2013 Mar;58(1):70-9. doi: 10.2478/s11686-013-0113-2. Epub 2013 Feb 2.
Cryptosporidium parvum is an intracellular parasite causing enteritis which can become life-threatening in immunocompromised host. Immunoregulatory T cells play a central role in the regulatory network of the host. Here, we proposed to characterize the populations of immune cells during infection an
PMID 23377915

Mycobacterium chelonae infection: a complication of tattooing.

Sergeant A, Conaglen P, Laurenson IF, Claxton P, Mathers ME, Kavanagh GM, Tidman MJ.SourceDepartment of Dermatology, Royal Infirmary of Edinburgh, Edinburgh, UK.
Clinical and experimental dermatology.Clin Exp Dermatol.2013 Mar;38(2):140-2. doi: 10.1111/j.1365-2230.2012.04421.x. Epub 2012 Jul 25.
We describe an outbreak of Mycobacterium chelonae infection in four young immunocompetent patients who were tattooed by the same artist. All had been previously tattooed without complication, but following the latest tattooing session, they all developed a very similar papular eruption confined to s
PMID 22831709

Japanese Journal

症例報告根尖性歯周炎が原因と考えられたFusobacteriumによる肝膿瘍の1例

藤田識志,吉澤要,丸山康弘 [他]
肝臓 54(8), 548-522, 2013-08
NAID 40019751890

基礎疾患のない患者に肺および脊椎病変をきたしたMycobacterium intracellulareによる非結核性抗酸菌症の1例

伊藤明広,橋本徹,石田直 [他]
結核 88(6), 559-564, 2013-06
NAID 40019728325

ヒト白血病細胞を用いたマウス subrenal capsule grafting の検討

武藤昌図
湘南工科大学紀要 47(1), 71-76, 2013-03-31
… Comparison of cell-growth among immunocompetent normal mice, immunosuppressed mice and immunodeficient mice (nude mice) using this assay procedure showed normal mice was out of order for the antitumor evaluation because severe invasion of host immune cells were observed at cell-gtafting site. …
NAID 110009576133

今月の症例免疫学的な背景なく広汎な帯状疱疹ウイルス脳炎を呈し剖検に至った81歳男性例

間野達雄,遠藤由理佳,中山貴博 [他]
日本内科学会雑誌 102(2), 440-443, 2013-02-10
NAID 40019592071

Related Pictures

Oncotarget | An immunocompetent mouse model of human glioblastoma The Immune System Chapter ppt video online download 5. Haematology Chapter 21 Nonspecific Body Defenses and Immunity - ppt download The Immune System P A R T A. - ppt download Chapters 20, 21. Lymphatic and Immune System - ppt video online download Immune Print Chapter 21 The Immune System: Innate and Adaptive Body Defenses flashcards