WordNet
- prescribed by or according to regulation; "regulation army equipment"
- (embryology) the ability of an early embryo to continue normal development after its structure has been somehow damaged or altered
- the state of being controlled or governed
- the act of bringing to uniformity; making regular (同)regularization, regularisation
- the act of controlling or directing according to rule; "fiscal regulations are in the hands of politicians" (同)regulating
- an authoritative rule (同)ordinance
- secure against; "immune from taxation as long as he resided in Bermuda"; "immune from criminal prosecution"
- a person who is immune to a particular infection
- relating to or conferring immunity (to disease or infection) (同)resistant
- (usually followed by `to'
- relating to the condition of immunity; "the immune system"
PrepTutorEJDIC
- 〈C〉『規則』,『規定』;法規,条例 / 〈U〉(…の)『規制』,『調整』《+『of』+『名』》 / 正規の,規定どおりの
- 免疫の / 《補語にのみ用いて》(影響・攻撃・義務・税などを)免れている《+『against』(『from, to』)+『名』》
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- 1. 薬剤および生物学的製剤による二次性免疫不全症 secondary immune deficiency induced by drugs and biologics
- 2. 適応細胞性免疫応答 the adaptive cellular immune response
- 3. 母体 - 胎児接点の免疫 immunology of the maternal fetal interface
- 4. 同種造血細胞移植後の免疫再構築のための戦略 strategies for immune reconstitution following allogeneic hematopoietic cell transplantation
- 5. 免疫グロブリンの使用における一般原則 general principles in the use of immune globulin
English Journal
- Effects of enzymatic hydrolysis on the allergenicity of whey protein concentrates.
- Duan C1, Yang L2, Li A3, Zhao R4, Huo G5.Author information 1Key Laboratory of Dairy Science, Ministry of Education, Northeast Agricultural University, Harbin 150030, China. duancui19841111@163.com.2Key Laboratory of Dairy Science, Ministry of Education, Northeast Agricultural University, Harbin 150030, China. ljyang01@eyou.com.3Key Laboratory of Dairy Science, Ministry of Education, Northeast Agricultural University, Harbin 150030, China. aili-mail@163.com.4Key Laboratory of Dairy Science, Ministry of Education, Northeast Agricultural University, Harbin 150030, China. 151290185@qq.com.5Key Laboratory of Dairy Science, Ministry of Education, Northeast Agricultural University, Harbin 150030, China. gchuo58@163.com.AbstractCow's milk whey consists of many protein components and some of them are antigens to human and known to modulate immune responses. Enzymatic hydrolysis is a useful method to modify proteins with allergenicity. The objective of this study was to identify whether the in vitro enzymatic hydrolysis could reduce the allergenicity of whey protein concentrates (WPC).In this study, WPC were hydrolyzed by trypsin and twenty-four BALB/c mice were divided into three groups and fed with WPC formula and WPC hydrolysates formula, while the control mice received milk-free diet.The results revealed that there was no significant difference between the body weights among all groups. WPC-fed mice produced an elevated spleen lymphocyte proliferation level than WPC hydrolysates-fed mice and also produced higher levels of WPC-specific IgE in intestinal tract and serum in comparison to WPC hydrolysates-fed mice and control group. Significant up-regulation of plasma histamine levels were also observed and showed the same trend with IgE. The secretions of IL-4 and IL-5 were significantly enhanced by WPC. WPC significantly suppressed the secretion of IFN-γ while hydrolysates of WPC significantly increased the secretion of IFN-γ compared to control group.These results suggest that hydrolysis may play a role to reduce the allergenicity of WPC.
- Iranian journal of allergy, asthma, and immunology.Iran J Allergy Asthma Immunol.2014 Aug;13(4):231-9.
- Cow's milk whey consists of many protein components and some of them are antigens to human and known to modulate immune responses. Enzymatic hydrolysis is a useful method to modify proteins with allergenicity. The objective of this study was to identify whether the in vitro enzymatic hydrolysis coul
- PMID 24659158
- Analysis of 52 Rab GTPases from channel catfish and their involvement in immune responses after bacterial infections.
- Wang R1, Zhang Y1, Liu S1, Li C1, Sun L1, Bao L1, Feng J1, Liu Z2.Author information 1The Fish Molecular Genetics and Biotechnology Laboratory, Aquatic Genomics Unit, School of Fisheries, Aquaculture and Aquatic Sciences, and Program of Cell and Molecular Biosciences, Auburn University, 203 Swingle Hall, Auburn, AL 36849, USA.2The Fish Molecular Genetics and Biotechnology Laboratory, Aquatic Genomics Unit, School of Fisheries, Aquaculture and Aquatic Sciences, and Program of Cell and Molecular Biosciences, Auburn University, 203 Swingle Hall, Auburn, AL 36849, USA. Electronic address: liuzhan@auburn.edu.AbstractRab genes, encoding a large family of monomeric G-proteins, contain over 60 members in the human genome. They have been recognized as crucial regulators for membrane trafficking including cargo sorting, vesicle formation, budding, motility, docking, fusion, secretory and endocytic pathway of host immune responses. However, little is known of the Rab gene family in teleost fish species. The development of full-length transcripts and whole genome sequences allow the identification and annotation of Rab GTPase gene family in catfish. In this study, a total of 52 Rab genes were identified from catfish cDNA and genome databases. Phylogenetic analysis assigned them into eleven subfamilies. Most Rab GTPases are conserved among vertebrates, though some of which are absent in fish genomes. Analysis of multiple RNA-seq datasets, along with real time PCR analysis revealed up-regulation of 10 Rab genes after bacterial infection. These included Rab3a, Rab4a, Rab4b, Rab5a, Rab5c, Rab7a, Rab9a, Rab11a, Rab11b, and Rab33a. Their up-regulation are temporally and spatially regulated in various tissues, but mostly induced at early stages after infection and in the gill and liver tissues, with the exception of Rab5c that is mostly up-regulated in the head kidney and trunk kidney. The complex pattern of their induced expression suggested both specific and cooperative actions of a these Rab genes in the acute immune responses to bacterial infection.
- Developmental and comparative immunology.Dev Comp Immunol.2014 Jul;45(1):21-34. doi: 10.1016/j.dci.2014.01.026. Epub 2014 Feb 7.
- Rab genes, encoding a large family of monomeric G-proteins, contain over 60 members in the human genome. They have been recognized as crucial regulators for membrane trafficking including cargo sorting, vesicle formation, budding, motility, docking, fusion, secretory and endocytic pathway of host im
- PMID 24513270
- Fish granulocytes express a constitutively active androgen receptor variant.
- Sánchez-Hernández M1, Arizcun M1, García-Alcázar A1, Sarropoulou E2, Mulero V3, García-Ayala A4.Author information 1Centro Oceanográfico de Murcia, Instituto Español de Oceanografía (IEO), Carretera de la Azohía s/n, Puerto de Mazarrón, 30860 Murcia, Spain.2Institute of Marine Biology and Genetics, Hellenic Center for Marine Research, Crete, Greece.3Department of Cell Biology and Histology, Faculty of Biology, Regional Campus of International Excellence "Campus Mare Nostrum", University of Murcia, 30100 Murcia, Spain. Electronic address: vmulero@um.es.4Department of Cell Biology and Histology, Faculty of Biology, Regional Campus of International Excellence "Campus Mare Nostrum", University of Murcia, 30100 Murcia, Spain. Electronic address: agayala@um.es.AbstractIn humans, alternative splicing of androgen receptor (AR) is usually involved in some diseases. However, our knowledge about the presence of AR variants in other species and its importance for immunity is scant. Here, we report the identification of a constitutively active AR variant lacking the ligand-binding domain (LBD), ARΔLBD, in the fish gilthead seabream. ARΔLBD is expressed in the testis and the head-kidney (HK), and its expression varies with the reproductive stage and is correlated with plasma testosterone (T). In addition, ARΔLBD is expressed in acidophilic granulocytes (AGs), which are the functional equivalent of mammalian neutrophils, but not in macrophages, and its expression is modulated by both T and immune stimuli. Notably, AR and ARΔLBD were able to interact, being the activity of AR dominant at all concentrations tested of the ligand. These results reveal a new mechanism for the regulation of neutrophil biology in vertebrates and explain the conflicting results that suggest that androgens are less important than AR in human and mouse neutrophil homeostasis.
- Developmental and comparative immunology.Dev Comp Immunol.2014 Jul;45(1):115-22. doi: 10.1016/j.dci.2014.01.024. Epub 2014 Feb 6.
- In humans, alternative splicing of androgen receptor (AR) is usually involved in some diseases. However, our knowledge about the presence of AR variants in other species and its importance for immunity is scant. Here, we report the identification of a constitutively active AR variant lacking the lig
- PMID 24509065
Japanese Journal
- 骨髄間葉系細胞移植による関節軟骨修復の可能性 (特集 次世代の膠原病治療)
- 分子リウマチ治療 9(3), 122-124, 2016-08
- NAID 40020919481
- Nonoverlapping roles of PD-1 and FoxP3 in maintaining immune tolerance in a novel autoimmune pancreatitis mouse model.
- Proceedings of the National Academy of Sciences of the United States of America 113(30), 8490-8495, 2016-07-07
- NAID 120005819493
- 腸管免疫細胞による代謝調節 (第1土曜特集 代謝調節における免疫細胞の役割)
- 医学のあゆみ 257(6), 711-717, 2016-05-07
- NAID 40020812834
Related Links
- 免疫アレルギー学分野 - The Department of Immune Regulation - ようこそ免疫アレルギー学研究室へ 免疫とは、生体内に侵入してきたウイルスや細菌などの病原体を排除したり、体の中にできたがん細胞をやっつけてくれたりする、我々が ...
- 免疫アレルギー学分野 - The Department of Immune Regulation - HOME » News News 2015年10月29日 Photo Galleryを更新しました。 2015年09月29日 研究業績を更新しました。 2015年06月27日 研究業績を更新しました。 2015年05 ...
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★リンクテーブル★
| リンク元 | 「免疫調節」「immune control」「免疫制御」 |
| 関連記事 | 「regulation」「immune」 |
「免疫調節」
「immune control」
「免疫制御」
「regulation」
- 関
- accommodation、accommodative、adjust、adjustment、baffle、control、modulate、modulation、regulate、regulatory
「immune」
- adj.
- 免疫の、免疫性の