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English Journal

Carr SM1, Munro S1, Zalmas LP1, Fedorov O2, Johansson C2, Krojer T2, Sagum CA3, Bedford MT3, Oppermann U2, La Thangue NB4.
Proceedings of the National Academy of Sciences of the United States of America.Proc Natl Acad Sci U S A.2014 Aug 5;111(31):11341-6. doi: 10.1073/pnas.1403737111. Epub 2014 Jul 21.
The retinoblastoma tumor suppressor protein pRb is a key regulator of cell cycle progression and mediator of the DNA damage response. Lysine methylation at K810, which occurs within a critical Cdk phosphorylation motif, holds pRb in the hypophosphorylated growth-suppressing state. We show here that
PMID 25049398

Arabidopsis CPL4 is an essential C-terminal domain phosphatase that suppresses xenobiotic stress responses.

Fukudome A1, Aksoy E, Wu X, Kumar K, Jeong IS, May K, Russell WK, Koiwa H.
The Plant journal : for cell and molecular biology.Plant J.2014 Jul 8. doi: 10.1111/tpj.12612. [Epub ahead of print]
Eukaryotic gene expression is both promoted and inhibited by the reversible phosphorylation of the C-terminal domain of RNA polymerase II (pol II CTD). More than 20 Arabidopsis genes encode CTD phosphatase homologs, including four CTD phosphatase-like (CPL) family members. Although in vitro CTD phos
PMID 25041272

Rojas-Sutterlin S1, Lecuyer E, Hoang T.
Current opinion in hematology.Curr Opin Hematol.2014 Jul;21(4):256-64. doi: 10.1097/MOH.0000000000000052.
PURPOSE OF REVIEW: KIT tyrosine kinase receptor is essential for several tissue stem cells, especially for hematopoietic stem cells (HSCs). Moderately decreased KIT signaling is well known to cause anemia and defective HSC self-renewal, whereas gain-of-function mutations are infrequently found in le
PMID 24857885

Serine/arginine-rich splicing factor 7 regulates p21-dependent growth arrest in colon cancer cells

High Loss of Heterozygosity of 9p24 Region and Identification of BRM as A Candidate Tumor Suppressor Gene in Head and Neck Cancer(International Symposium of Maxillofacial and Oral Regenerative Biology in Okayama 2005)

Involvement of Down-Regulation of Cdk2 Activity in Hepatocyte Growth Factor-Induced Cell Cycle Arrest at G1 in the Human Hepatocellular Carcinoma Cell Line HepG2