hyperprolactinemia

出典: meddic

高プロラクチン血症

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出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2015/10/20 07:06:54」(JST)

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英文文献

  • Effects of metoclopramide on mRNA levels of steroid 5α-reductase isozymes in prostate of adult rats.
  • Sánchez P, Torres JM, Castro B, Frías JF, Ortega E.SourceDepartment of Biochemistry and Molecular Biology, Faculty of Medicine, University of Granada, Avda. de Madrid s/n, 18012, Granada, Spain, pilarsan@ugr.es.
  • Journal of physiology and biochemistry.J Physiol Biochem.2013 Mar;69(1):133-40. doi: 10.1007/s13105-012-0197-4. Epub 2012 Jul 18.
  • The rising incidence of prostate cancer and benign prostatic hypertrophy in the Western world is a cause of increasing public health concern. The most active androgen in the prostate is 5α-dihydrotestosterone obtained from testosterone (T) by the enzyme 5α-reductase (5α-R), expressed in the prost
  • PMID 22806172
  • Bone Loss Associated with Hyperprolactinemia in Patients with Schizophrenia.
  • Kinon BJ, Liu-Seifert H, Stauffer VL, Jacob J.SourceLilly Corporate Center, Eli Lilly and Company, Indianapolis, IN 46285, USA.
  • Clinical schizophrenia & related psychoses.Clin Schizophr Relat Psychoses.2013 Feb 8:1-27. [Epub ahead of print]
  • Background: Elevated prolactin (hyperprolactinemia) has been commonly reported during treatment with some antipsychotic drugs. A decrease in bone mineral density (BMD) may be related to elevated prolactin. The objective of this study was to determine the prevalence of low BMD in patients with schizo
  • PMID 23395836
  • Primary adult infradiaphragmatic craniopharyngiomas: Clinical features, management and outcomes in one Chinese institution.
  • Wang L, Ni M, Jia W, Jia G, Du J, Li G, Zhang J, Wang Z.SourceDepartment of Neurosurgery, Beijing Tiantan Hospital, and Department of Neuropathology, Beijing Neurosurgical Institute, Capital Medical University, Beijing, P R China. Electronic address: saintage7@126.com.
  • World neurosurgery.World Neurosurg.2013 Feb 5. pii: S1878-8750(13)00276-3. doi: 10.1016/j.wneu.2013.02.011. [Epub ahead of print]
  • OBJECTIVE: : This study was designed to evaluate the clinical, radiologic, histologic and surgical outcome characteristics of this disease treated in a single institution.METHODS: : 16 adult patients underwent trans-sphenoidal microsurgery from October 2005 to December 2010 at Neurosurgical Center o
  • PMID 23396074

和文文献

  • 薬剤性高プロラクチン血症が原因と考えられた男性不妊症の1例
  • 竹島 徹平,黒田 晋之介,小林 将貴 [他],加藤 喜健,湯村 寧,野口 和美,岩崎 晧
  • 泌尿器科紀要 = Acta urologica Japonica 59(1), 65-67, 2013-01-00
  • … He was diagnosed with oligozoospermia, asthenozoospermia and hyperprolactinemia probably induced by sulpiride for depression, because semen quality gradually improved after cessation of sulpiride administration. …
  • NAID 120005241420
  • Pharmacological Treatment for Pituitary Adenomas
  • 富永 篤,木下 康之,碓井 智,栗栖 薫
  • Japanese Journal of Neurosurgery 22(2), 101-108, 2013
  • … Dopamine agonists have high normalization rate of hyperprolactinemia ; …
  • NAID 130003379591
  • Severe oligozoospermia in a patient with myxedema coma
  • KOMIYA Akira,WATANABE Akihiko,KAWAUCHI Yoko,TAKANO Atsuko,FUSE Hideki
  • Reproductive medicine and biology 11(4), 207-211, 2012-10-01
  • NAID 10031123423

関連リンク

Hyperprolactinemia is a condition of elevated serum prolactin. Prolactin is a 198-amino acid protein (23-kd) produced in the lactotroph cells of the anterior pituitary gland. ... Frequency United States This condition occurs ...
Physiological hyperprolactinemia is usually mild or moderate. During normal pregnancy, serum prolactin rises progressively to around 200-500 ng/mL. Many common medications cause hyperprolactinemia usually with prolactin levels ...

関連画像

Hyperprolactinemia; Prolactin and Pathological Hyperprolactinemia Hyperprolactinemia; Prolactin  to diagnosis of hyperprolactinemiaHyperprolactinemia: Etiology, Diagnosis  Prolactin Levels (Hyperprolactinemia


★リンクテーブル★
リンク元高プロラクチン血症」「hyperprolactinemic
拡張検索latent hyperprolactinemia」「occult hyperprolactinemia

高プロラクチン血症」

  [★]

hyperprolactinemia
プロラクチン

病因

高プロラクチン血症をきたす病態

IMD.933
  • 視床下部下垂体茎障害
  • 異所性PRL産生腫瘍
  • PRLの産生を促進する薬物
  • 機能性高PRL血漿
  • 分娩と無関係

分類

日中正常で、夜間のみ高プロラクチン血症を呈するもの

病態生理

SP.890
1. → (乳腺)乳汁漏出、男性でも乳房肥大
2. → GnRHの産生・放出を抑制 → 性腺機能低下 → 性腺ホルモン分泌低下 → 性欲低下、(女性)排卵・月経周期の異常、(男性)精子産生の異常

症状

HIM.2205
  • 男性:性欲減退、不妊、失明(視神経の圧迫があれば)。ゴナドトロピンの抑制により、テストステロンの低下、インポテンス、精子減少をきたす。長期間ゴナドトロピンの低下が持続すれば、骨減少症、筋肉量の減少、ヒゲの成長速度減少がみられる。
  • 女性:無月経、乳汁漏出(80%の症例)、不妊。

検査

  • ゴナドトロピン低値(FSH, LSH抑制)

治療

薬物療法

国試



hyperprolactinemic」

  [★]

  • 高プロラクチン血症の
hyperprolactinemia

latent hyperprolactinemia」

  [★] 潜在性高プロラクチン血症

occult hyperprolactinemia」

  [★] 潜在性高プロラクチン血症



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