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WordNet
- a straight line that generates a cylinder or cone
- one of four substances thought in ancient and medieval cosmology to constitute the physical universe; "the alchemists believed that there were four elements"
- the situation in which you are happiest and most effective; "in your element"
- the most favorable environment for a plant or animal; "water is the element of fishes"
- a result; "this situation developed in response to events in Africa"
- a phrase recited or sung by the congregation following a versicle by the priest or minister
- the manner in which an electrical or mechanical device responds to an input signal or a range of input signals
- the secretion of an endocrine gland that is transmitted by the blood to the tissue on which it has a specific effect (同)endocrine, internal_secretion
- violent or severe weather (viewed as caused by the action of the four elements); "they felt the full fury of the elements"
PrepTutorEJDIC
- 〈C〉(物質を構成する)元素 / 〈C〉《修飾語[句]を伴って》(…の)(基本的な)『要素』,『成分』;《しばしば複数形で》構成分子 / 〈C〉(生物に固有の)生息場所,環境;(人の)適所,本領 / 〈C〉《古》四大(しだい)[元素](自然界の基本的構成要素と考えられていた地(earth)・水(water)・風(air)・火(fire)の4大要素の一つ) / 《the elements》(雨・風・雪などの)自然力・風雨,(特に)悪天候 / 《the elements》(学問の)原理,初歩,概論
- 〈C〉(…に対する)『返事』,『返答』《+『to』+『名』》 / 〈C〉〈U〉(…に対する)『反応』,『反響』《『to』+『名』》 / 〈C〉応答歌,応唱(牧師にならって合唱隊・会衆が短い祈り・歌を応答すること)
- ホルモン
Wikipedia preview
出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2014/07/21 17:30:01」(JST)
[Wiki en表示]
A hormone response element (HRE) is a short sequence of DNA within the promoter of a gene that is able to bind a specific hormone receptor complex and therefore regulate transcription.[1] The sequence is most commonly a pair of inverted repeats separated by three nucleotides, which also indicates that the receptor binds as a dimer. Specifically, HRE responds to steroid hormones, as the activated steroid receptor is the transcription factor binding HRE. This upregulates transcription of genes signaled by the steroid hormone.
A gene may have many different response elements, allowing complex control to be exerted over the level and rate of transcription.[2]
HRE are used in transgenic animal cells as inducers of gene expression.
References
- ^ "Steroid Hormone Receptors and their Response Elements". Retrieved 2006-11-09.
- ^ Monty Krieger; Matthew P Scott; Matsudaira, Paul T.; Lodish, Harvey F.; Darnell, James E.; Lawrence Zipursky; Kaiser, Chris; Arnold Berk (2003). Molecular Cell Biology, Fifth Edition. San Francisco: W. H. Freeman. p. 973 pages. ISBN 0-7167-4366-3.
UpToDate Contents
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English Journal
- Daily rhythms of the expression of genes from the somatotropic axis: The influence on tilapia (Oreochromis niloticus) of feeding and growth hormone administration at different times.
- Costa LS1, Rosa PV2, Fortes-Silva R3, Sánchez-Vázquez FJ4, López-Olmeda JF5.
- Comparative biochemistry and physiology. Toxicology & pharmacology : CBP.Comp Biochem Physiol C Toxicol Pharmacol.2016 Mar-Apr;181-182:27-34. doi: 10.1016/j.cbpc.2015.12.008. Epub 2015 Dec 29.
- The aim of this research was to investigate the presence of daily rhythms in the somatotropic axis of tilapia fed at two times (mid-light, ML or mid-dark, MD) and the influence of the time of day of growth hormone (GH) administration on the response of this axis. Two different GH injection times wer
- PMID 26743958
- Maternal dexamethasone exposure ameliorates cognition and tau pathology in the offspring of triple transgenic AD mice.
- Di Meco A1, Joshi YB1, Lauretti E1, Praticò D1.
- Molecular psychiatry.Mol Psychiatry.2016 Mar;21(3):403-10. doi: 10.1038/mp.2015.78. Epub 2015 Jun 16.
- Dysregulation of stress hormones, such as glucocorticoids, in adult life increases the risk to develop Alzheimer's disease (AD). However, the effect of prenatal glucocorticoids exposure on AD development in the offspring remains unknown. We studied how gestational dexamethasone exposure influences t
- PMID 26077691
- RORα switches transcriptional mode of ERRγ that results in transcriptional repression of CYP2E1 under ethanol-exposure.
- Han YH1, Kim DK2, Na TY1, Ka NL1, Choi HS3, Lee MO4.
- Nucleic acids research.Nucleic Acids Res.2016 Feb 18;44(3):1095-104. doi: 10.1093/nar/gkv1034. Epub 2015 Oct 12.
- Increased cytochrome P450 2E1 (CYP2E1) expression is the main cause of oxidative stress, which exacerbates alcoholic liver diseases (ALDs). Estrogen-related receptor gamma (ERRγ) induces CYP2E1 expression and contributes to enhancing alcohol-induced liver injury. Retinoic acid-related orphan recept
- PMID 26464440
Japanese Journal
- A cis-acting element in the coding region of cyclin B1 mRNA couples subcellular localization to translational timing
- Yasuda Kyota,Kotani Tomoya,Yamashita Masakane
- Developmental biology 382(2), 517-529, 2013-10-15
- … In immature zebrafish oocytes, translationally repressed cyclin B1 mRNA is localized to the animal polar cytoplasm and its temporally regulated translational activation in response to a maturationAnducing hormone is essential to promote oocyte maturation. …
- NAID 120005348193
- The Mechanisms of Electroconvulsive Stimuli in BrdU-Positive Cells of the Dentate Gyrus in ACTH-Treated Rats
- Kuwatsuka Keiko,Hayashi Hiromi,Onoue Yuka [他],Miyazaki Ikuko,Koyama Toshihiro,Asanuma Masato,Kitamura Yoshihisa,Sendo Toshiaki
- Journal of Pharmacological Sciences 122(1), 34-41, 2013
- … In a previous study, treatment with adrenocorticotropic hormone (ACTH) for 14 days decreased adult hippocampal cell proliferation. …
- NAID 130003362700
- The Effect of Sex Hormones on Peroxisome Proliferator-Activated Receptor Gamma Expression and Activity in Mature Adipocytes
- Sato Hiromi,Sugai Hana,Kurosaki Hiroshi [他],Ishikawa Momoko,Funaki Asami,Kimura Yuki,Ueno Koichi
- Biological and Pharmaceutical Bulletin 36(4), 564-573, 2013
- … Finally a luciferase assay was performed using a PPAR response element-Luk reporter gene. … Transcriptional activity was not changed by any of single sex hormone treatment, but was significantly downregulated by co-treatment with pioglitazone and DHT. …
- NAID 130003361388
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- 要素、成分、素。(構成)分子。(科学)元素、(数)(集合の)要素、元素、素。(行列の)要素、成分。(図形を火tが千都来る)要素。(文法の)要素
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- basal、bases、basic、basis、component、composition、constituent、elementary、factor、fundamentals、ingredient、moiety
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