homeotic gene

出典: meddic


homeo box、homeoboxhomeobox gene

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出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2013/06/18 20:57:39」(JST)

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  • Axis inhibition protein 2 polymorphisms may be a risk factor for families with isolated oligodontia.
  • Qin H1, Cai J2.
  • Molecular medicine reports.Mol Med Rep.2015 Mar;11(3):1899-904. doi: 10.3892/mmr.2014.2900. Epub 2014 Nov 7.
  • The objective of the present study was to search for Msh homeobox 1 (MSX1), paired box gene 9 (PAX9), ectodysplasin‑A (EDA) and axis inhibition protein 2 (AXIN2) variants in a family with isolated oligodontia and analyse the pathogenesis of mutations that result in oligodontia phenotypes. Member
  • PMID 25377791
  • Epigenetic modification of MiR-429 promotes liver tumour-initiating cell properties by targeting Rb binding protein 4.
  • Li L1, Tang J1, Zhang B2, Yang W1, LiuGao M1, Wang R3, Tan Y1, Fan J4, Chang Y3, Fu J1, Jiang F3, Chen C3, Yang Y1, Gu J5, Wu D5, Guo L1, Cao D1, Li H3, Cao G6, Wu M2, Zhang MQ5, Chen L1, Wang H7.
  • Gut.Gut.2015 Jan;64(1):156-67. doi: 10.1136/gutjnl-2013-305715. Epub 2014 Feb 26.
  • OBJECTIVE: Liver tumour-initiating cells (T-ICs) are critical for hepatocarcinogenesis. However, the underlying mechanism regulating the function of liver T-ICs remains unclear.METHODS: Tissue microarrays containing 242 hepatocellular carcinoma (HCC) samples were used for prognostic analysis. Magnet
  • PMID 24572141
  • Arabidopsis thaliana homeobox 12 (ATHB12), a homeodomain-leucine zipper protein, regulates leaf growth by promoting cell expansion and endoreduplication.
  • Hur YS1, Um JH, Kim S, Kim K, Park HJ, Lim JS, Kim WY, Jun SE, Yoon EK, Lim J, Ohme-Takagi M, Kim D, Park J, Kim GT, Cheon CI.
  • The New phytologist.New Phytol.2015 Jan;205(1):316-28. doi: 10.1111/nph.12998. Epub 2014 Sep 3.
  • Arabidopsis thaliana homeobox 12 (ATHB12), a homeodomain-leucine zipper class I (HD-Zip I) gene, is highly expressed in leaves and stems, and induced by abiotic stresses, but its role in development remains obscure. To understand its function during plant development, we studied the effects of loss
  • PMID 25187356


  • Ectopic expression of an AP3-like and a PI-like genes from 'Sekkoku' orchid (Dendrobium moniliforme) causes the homeotic conversion of sepals to petals in whorl 1 and the suppression of carpel development in whorl 4 in Arabidopsis flowers
  • SIRISAWAT Supatida,EZURA Hiroshi,FUKUDA Naoya,KOUNOSU Takahiro,HANDA Takashi
  • Plant biotechnology 27(2), 183-192, 2010-06-25
  • … Three class-B MADS-box genes, the paleotype AP3 genes DMAP3A and DMAP3B, and the PI-like gene DMPI, were isolated from a native orchid in Japan named ‘Sekkoku’ (Dendrobium moniliforme) and ectopically expressed in Arabidopsis. …
  • NAID 10026527239
  • The spatial expression patterns of DROOPING LEAF orthologs suggest a conserved function in grasses
  • ISHIKAWA Motokazu,OHMORI Yoshihiro,TANAKA Wakana,HIRABAYASHI Chizuru,MURAI Koji,OGIHARA Yasunari,YAMAGUCHI Takahiro,HIRANO Hiro-Yuki
  • Genes & genetic systems 84(2), 137-146, 2009-04-25
  • … The DROOPING LEAF (DL) gene regulates carpel specification in the flower and midrib formation in the leaf in Oryza sativa (rice). … Loss-of-function mutations in the dl locus cause homeotic transformation of carpels into stamens and lack of midrib, resulting in the drooping leaf phenotype. … DL is a member of the YABBY gene family and is closely related to the CRABS CLAW (CRC) gene in Arabidopsis thaliana. …
  • NAID 10024791705


Homeotic genes are genes that determine which parts of the body form what body parts. One example are the Hox and ParaHox genes which are important for segmentation, another example is the MADS-box-containing genes in the ABC ...
Any of a group of genes that control the pattern of body formation during early embryonic development of organisms. These genes encode proteins called transcription factors that direct cells to form various...



リンク元ホメオティック遺伝子」「ホメオ遺伝子」「homeobox gene



WordNet   license wordnet

「one of various similar homeotic genes that are involved in bodily segmentation during embryonic development」
homeobox gene



homeotic gene
  • ホメオティック変異を引き起こす遺伝子
  • 発生段階において、ある体節に分布する細胞集団の運命を、将来的に特定の構造を形成しうる細胞へ分化するように方向付ける機能を持った調節遺伝子。ホメオドメインと呼ばれるDNA結合モチーフを持った核内タンパク質(転写因子として機能?)をコードしている。
  • 哺乳類ではホメオティック遺伝子群を4つ持ち、HoxA, HoxB, HoxC, HoxDとよばれる。



homeotic gene

homeobox gene」


homeo box、homeoboxhomeotic gene


  [★] 遺伝子

WordNet   license wordnet

「(genetics) a segment of DNA that is involved in producing a polypeptide chain; it can include regions preceding and following the coding DNA as well as introns between the exons; it is considered a unit of heredity; "genes were formerly called factors"」
cistron, factor

PrepTutorEJDIC   license prepejdic




WordNet   license wordnet

「informal term for information; "give me the gen on your new line of computers"」