hippuric acid

出典: meddic

馬尿酸

Wikipedia preview

出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2015/10/28 14:46:01」(JST)

wiki en

[Wiki en表示]

UpToDate Contents

全文を閲覧するには購読必要です。 To read the full text you will need to subscribe.

英文文献

  • Consumption of Hibiscus sabdariffa L. aqueous extract and its impact on systemic antioxidant potential in healthy subjects.
  • Frank T, Netzel G, Kammerer DR, Carle R, Kler A, Kriesl E, Bitsch I, Bitsch R, Netzel M.SourcePrivate Consultant, 65812 Bad Soden, Germany.
  • Journal of the science of food and agriculture.J Sci Food Agric.2012 Aug 15;92(10):2207-18. doi: 10.1002/jsfa.5615. Epub 2012 Feb 13.
  • BACKGROUND: To evaluate health benefits attributed to Hibiscus sabdariffa L. a randomized, open-label, two-way crossover study was undertaken to compare the impact of an aqueous H. sabdariffa L. extract (HSE) on the systemic antioxidant potential (AOP; assayed by ferric reducing antioxidant power (F
  • PMID 22331521
  • The glycine deportation system and its pharmacological consequences.
  • Beyoğlu D, Idle JR.AbstractThe glycine deportation system is an essential component of glycine catabolism in man whereby 400 to 800mg glycine per day are deported into urine as hippuric acid. The molecular escort for this deportation is benzoic acid, which derives from the diet and from gut microbiota metabolism of dietary precursors. Three components of this system, involving hepatic and renal metabolism, and renal active tubular secretion help regulate systemic and central nervous system levels of glycine. When glycine levels are pathologically high, as in congenital nonketotic hyperglycinemia, the glycine deportation system can be upregulated with pharmacological doses of benzoic acid to assist in normalization of glycine homeostasis. In congenital urea cycle enzymopathies, similar activation of the glycine deportation system with benzoic acid is useful for the excretion of excess nitrogen in the form of glycine. Drugs which can substitute for benzoic acid as substrates for the glycine deportation system have adverse reactions that may involve perturbations of glycine homeostasis. The cancer chemotherapeutic agent ifosfamide has an unacceptably high incidence of encephalopathy. This would appear to arise as a result of the production of toxic aldehyde metabolites which deplete ATP production and sequester NADH in the mitochondrial matrix, thereby inhibiting the glycine deportation system and causing de novo glycine synthesis by the glycine cleavage system. We hypothesize that this would result in hyperglycinemia and encephalopathy. This understanding may lead to novel prophylactic strategies for ifosfamide encephalopathy. Thus, the glycine deportation system plays multiple key roles in physiological and neurotoxicological processes involving glycine.
  • Pharmacology & therapeutics.Pharmacol Ther.2012 Aug;135(2):151-67. Epub 2012 May 11.
  • The glycine deportation system is an essential component of glycine catabolism in man whereby 400 to 800mg glycine per day are deported into urine as hippuric acid. The molecular escort for this deportation is benzoic acid, which derives from the diet and from gut microbiota metabolism of dietary pr
  • PMID 22584143

和文文献

  • Direct inhibition and down-regulation by uremic plasma components of hepatic uptake transporter for sn-38, an active metabolite of irinotecan, in humans
  • Fujita Ken-ichi,Sugiura Tomoko,Okumura Hidenori,Umeda Saki,Nakamichi Noritaka,Watanabe Yusuke,Suzuki Hiromichi,Sunakawa Yu,Shimada Ken,Kawara Kaori,Sasaki Yasutsuna,Kato Yukio
  • Pharmaceutical Research 31(1), 204-215, 2014-01
  • … Methods: We evaluated SN-38 uptake and its inhibition by uremic toxins, 3-carboxy-4-methyl-5-propyl-2-furanpropionate (CMPF), indoxyl sulfate (Indox), hippuric acid (HA) and indole acetate (IA), with cryopreserved human hepatocytes and HEK293 cells stably expressing hepatic uptake transporters, organic anion transporting polypeptides (OATPs). …
  • NAID 120005385991
  • Correlation between Serum Levels of Protein-Bound Uremic Toxins in Hemodialysis Patients Measured by LC/MS/MS
  • Itoh Yoshiharu,Ezawa Atsuko,Kikuchi Kaori,Tsuruta Yoshinari,Niwa Toshimitsu
  • Mass Spectrometry 2(Special_Issue), S0017-S0017, 2013
  • … Serum concentration of protein-bound uremic toxins such as indoxyl sulfate, indoxyl glucuronide, indoleacetic acid, p-cresyl sulfate, p-cresyl glucuronide, phenyl sulfate, phenyl glucuronide, phenylacetic acid, phenylacetylglutamine, hippuric acid, 4-ethylphenyl sulfate, and 3-carboxy-4-methyl-5-propyl-2-furanpropionic acid (CMPF) in hemodialysis patients were simultaneously measured by liquid chromatography/tandem mass spectrometry. …
  • NAID 130003380185
  • 有機溶剤中毒予防のための尿中馬尿酸の光学的検知の研究 : 馬尿酸溶液の近赤外吸光スペクトルの検討
  • 西田 亘児,小川 充洋,斎藤 淳夫 [他],范 宇亭,本井 幸介,山越 健弘,山越 憲一
  • 電子情報通信学会技術研究報告. MBE, MEとバイオサイバネティックス 111(57), 9-13, 2011-05-13
  • 有機溶剤として広く用いられるトルエンの最終代謝物は馬尿酸であり,トルエン作業者の尿中には馬尿酸が含まれる.この尿中馬尿酸はトルエン暴露の指標となるため,トルエン作業者には尿検査が義務づけられている.現在,こうした計測のためにはHPLCなどが用いられているが,本研究では,簡便で即時にできる検査の開発を目指し,近赤外吸光スペクトラム計測に着目した.今回,馬尿酸水溶液の近赤外吸光スペクトルを計測し,純水 …
  • NAID 110008726107

関連リンク

hippuric acid [hĭ-pu´rik] a compound formed by conjugation of benzoic acid and glycine; it occurs in the urine of herbivorous animals, rarely in human urine. hip·pu·ric ac·id (hi-pyūr'ik as'id), A detoxification and excretory product of ...
NIOSH Manual of Analytical Methods (NMAM), Fourth Edition HIPPURIC and METHYL HIPPURIC ACIDS in urine 8301 (1) hippuric acid C 6 H 5 CONHCH 2 CO 2 H FW: 179.18 CAS: 495-69-2 RTECS: MR815000 (2) 2 ...

関連画像


押しても画像が表示されない場合はサーバが混雑しています。2週間ほどあけて、再度押下してください。


★リンクテーブル★
リンク元馬尿酸」「hippurate
拡張検索aminohippuric acid」「p-aminohippuric acid」「methylhippuric acid in urine
関連記事acid

馬尿酸」

  [★]

hippurate, hippuric acid
Nα-ベンゾイルグリシン
グリシン抱合
  • 構造式:C6H5CONHCH2COOH


hippurate」

  [★]

  • n.
hippuric acid

aminohippuric acid」

  [★]

aminohippuratep-aminohippuric acid

p-aminohippuric acid」

  [★] パラアミノ馬尿酸 PAH


methylhippuric acid in urine」

  [★] 尿中メチル馬尿酸


acid」

  [★]

WordNet   license wordnet

「street name for lysergic acid diethylamide」
back breaker, battery-acid, dose, dot, Elvis, loony toons, Lucy in the sky with diamonds, pane, superman, window pane, Zen

WordNet   license wordnet

「any of various water-soluble compounds having a sour taste and capable of turning litmus red and reacting with a base to form a salt」

WordNet   license wordnet

「having the characteristics of an acid; "an acid reaction"」

PrepTutorEJDIC   license prepejdic

「酸性の / 酸味のある,すっぱい(sour) / (言葉・態度などが)厳しい,しんらつな / 酸 / すっぱいもの / 《俗》=LSD」




★コメント★

[メモ入力エリア]
※コメント5000文字まで
ニックネーム:
コメント:




表示
個人用ツール


  meddic.jp

リンク
連絡