high density lipoprotein

出典: meddic

高比重リポ蛋白 HDL

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出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2012/12/27 14:31:27」(JST)

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  • Novel anti-diabetic effect of SCM-198 via inhibiting the hepatic NF-κB pathway in db/db mice.
  • Huang H, Xin H, Liu X, Xu Y, Wen D, Zhang Y, Zhu YZ.SourceDepartment of Pharmacology, School of Pharmacy and Institute of Biomedical Sciences, Fudan University, Shanghai Chempartner Co. Ltd, Shanghai 201203, People's Republic of China.
  • Bioscience reports.Biosci Rep.2012 Apr 1;32(2):185-95.
  • There are reports of early evidence that suggest the involvement of chronic low-grade inflammation in the pathogenesis of Type 2 diabetes. Thus, substances that have effects in reducing inflammation could be potential drugs for Type 2 diabetes. Leonurine (4-guanidino-n-butyl syringate; SCM-198) is
  • PMID 21859425
  • Characterisation of phenols and antioxidant and hypolipidaemic activities of Lethariella cladonioides.
  • Wei AH, Zhou DN, Ruan JL, Cai YL, Xiong CM, Li MX.SourceKey Laboratory of Natural Medicinal Chemistry and Resource Evaluation of Hubei Province, College of Pharmacy, Huazhong University of Science and Technology, Wuhan 430030, China.
  • Journal of the science of food and agriculture.J Sci Food Agric.2012 Jan 30;92(2):373-9. doi: 10.1002/jsfa.4601. Epub 2011 Sep 14.
  • BACKGROUND: This study aimed to investigate the antioxidant and hypolipidaemic activities of an ethanol extract of Lethariella cladonioides (Nyl.) Krog (EE) and to characterise its chemical constituents.RESULTS: Nine phenols were identified as canarione, thamnolic acid, squamatic acid, vermicularin,
  • PMID 21918996


  • Efficacy and Safety of Cholesteryl Ester Transfer Protein Inhibitor Evacetrapib Administered as Monotherapy in Japanese Patients With Primary Hypercholesterolemia
  • Circulation journal : official journal of the Japanese Circulation Society 81(11), 1686-1692, 2017-11
  • NAID 40021354413
  • Role of the Low-Density Lipoprotein-Cholesterol/High-Density Lipoprotein-Cholesterol Ratio in Predicting Serial Changes in the Lipid Component of Coronary Plaque
  • Circulation journal : official journal of the Japanese Circulation Society 81(10), 1439-1446, 2017-10
  • NAID 40021323631
  • CETP阻害薬に望みはないのか?


High-density lipoprotein (HDL) is one of the five major groups of lipoproteins. Lipoproteins are complex particles composed of multiple proteins which transport all fat molecules (lipids) around the body within the water outside cells.
WebMD looks at HDL cholesterol, or ... What Makes HDL Cholesterol so Good? HDL is short for high-density lipoprotein. Each bit of HDL cholesterol is a microscopic blob that consists of a rim of lipoprotein surrounding ...


As it travels throughout theHigh density lipoprotein particle - Stock High-Density Lipoprotein MetabolismHigh-Density Lipoprotein HDL Diagram ChienLab - Gracie's Science PageCholesterol_&_Plasma_Lipoproteins.jpg

拡張検索familial high-density lipoprotein deficiency」「pre-beta high-density lipoprotein」「high-density lipoprotein」「high density lipoprotein cholesterol」「high density lipoprotein-cholesterol
関連記事high」「density」「hi」「lipoprotein」「high density



high-density lipoprotein, HDL lipoprotein, HDL
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  • コレステロールを末梢から肝臓に戻すコレステロール逆転送に関わっている。


  • 性別:女性>男性  ← エストロゲンの作用による? 閉経後には女性でも上昇する。
  • 血中TG濃度:逆相関するらしい
  • CETP濃度:逆相関するらしい


  • 原発性:アポA-I欠損症、LCAT欠損症、Tangier病、LPL欠損症
  • 続発性:喫煙、多価不飽和脂肪酸の過剰摂取、糖尿病、甲状腺疾患、肝硬変、慢性腎不全、プロブコール


  • 体重減少、有酸素運動、喫煙、少量のアルコール飲酒


  • 低HDL-C血症:40mg/dL以下
  • 動脈硬化のリスクファクター
  • 高HDL-C血症


  [★] 高比重リポ蛋白 high-density lipoprotein high density lipoprotein

familial high-density lipoprotein deficiency」

  [★] 家族性高密度リポ蛋白質欠損症

pre-beta high-density lipoprotein」


  • プレβ高密度リ・タンパク質

high-density lipoprotein」

  [★] 高比重リポ蛋白, HDL

high density lipoprotein cholesterol」

  [★] HDLコレステロール

high density lipoprotein-cholesterol」

  [★] HDLコレステロール



  • adj.
advancedaltitudehigh degreehigh levelhigh-gradehighlytall

WordNet   license wordnet

「in or to a high position, amount, or degree; "prices have gone up far too high"」

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「a state of altered consciousness induced by alcohol or narcotics; "they took drugs to get a high on"」

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「a state of sustained elation; "I''m on a permanent high these days"」

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「an air mass of higher than normal pressure; "the east coast benefits from a Bermuda high"」

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「a lofty level or position or degree; "summer temperatures reached an all-time high"」

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「a high place; "they stood on high and observed the countryside"; "he doesn''t like heights"」

PrepTutorEJDIC   license prepejdic

「『高い』,高い所にある / 《数の後に置いて》高さが…ある / (数量・程度などが標準より)『高い』,大きい,激しい / (身分・地位が)『高い』,高貴な / 『気高い』,高潔な / (声の調子が)『高い』,鋭い / 値段の高い,金の掛かる,ぜいたくな / 楽しい,陽気な,上得意の / (時・季節が)盛りの,たけなわの / (色が)濃い,赤い / 《話》(酒・麻薬などに)酔って / 『高く』,高い所に / (価値・程度などが)高く,高度に,激しく / 〈C〉《話》高水準,高値 / 〈U〉(自動車の)高速ギア / 〈C〉《話》(麻薬などによる)酔った状態」

WordNet   license wordnet

「at a great altitude; "he climbed high on the ladder"」
high up

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「used of sounds and voices; high in pitch or frequency」

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「happy and excited and energetic」
in high spirits

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「slightly and pleasantly intoxicated from alcohol or a drug (especially marijuana)」

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「in a rich manner; "he lives high"」
richly, luxuriously

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「(literal meaning) being at or having a relatively great or specific elevation or upward extension (sometimes used in combinations like `knee-high'」

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「far up toward the source; "he lives high up the river"」

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「greater than normal in degree or intensity or amount; "a high temperature"; "a high price"; "the high point of his career"; "high risks"; "has high hopes"; "the river is high"; "he has a high opinion of himself"」



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「the amount per unit size」

PrepTutorEJDIC   license prepejdic

「〈U〉『密集』;『密度』,濃さ / 〈U〉〈C〉(物質の)密度,濃度,比重 / 〈U〉《話》頭の鈍さ,愚鈍さ」



PrepTutorEJDIC   license prepejdic

「《話》(あいさつとして)『やあ』,こんにちは / 《英》(注意を促す発声として)おい,ちょっと(hey)」


  [★] リポ蛋白 lipoprotein

WordNet   license wordnet

「a conjugated protein having a lipid component; the principal means for transporting lipids in the blood」

high density」