glutamate receptor antagonist

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excitatory amino acid antagonistglutamate antagonist

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  • IVIG immunotherapy protects against synaptic dysfunction in Alzheimer's disease through complement anaphylatoxin C5a-mediated AMPA-CREB-C/EBP signaling pathway.
  • Gong B, Pan Y, Zhao W, Knable L, Vempati P, Begum S, Ho L, Wang J, Yemul S, Barnum S, Bilski A, Gong BY, Pasinetti GM.SourceDepartment of Neurology, Center of Excellence for Novel Approaches to Neurotherapeutics, Mount Sinai School of Medicine, New York, NY 10029, United States.
  • Molecular immunology.Mol Immunol.2013 Dec 31;56(4):619-29. doi: 10.1016/j.molimm.2013.06.016. Epub 2013 Aug 1.
  • BACKGROUND: Complement component C5-derived C5a locally generated in the brain has been shown to protect against glutamate-induced neuronal apoptosis and beta-amyloid (Aβ) toxicity, but the mechanism is not clear. In this study, we tested the hypothesis that C5a influences upstream signal transduct
  • PMID 23911420
  • Scopolamine rapidly increases Mammalian target of rapamycin complex 1 signaling, synaptogenesis, and antidepressant behavioral responses.
  • Voleti B, Navarria A, Liu RJ, Banasr M, Li N, Terwilliger R, Sanacora G, Eid T, Aghajanian G, Duman RS.SourceLaboratory of Molecular Psychiatry, Center for Genes and Behavior, Departments of Psychiatry, Neurobiology, and Laboratory Medicine, Yale University School of Medicine, New Haven, Connecticut.
  • Biological psychiatry.Biol Psychiatry.2013 Nov 15;74(10):742-9. doi: 10.1016/j.biopsych.2013.04.025. Epub 2013 Jun 14.
  • BACKGROUND: Clinical studies report that scopolamine, an acetylcholine muscarinic receptor antagonist, produces rapid antidepressant effects in depressed patients, but the mechanisms underlying the therapeutic response have not been determined. The present study examines the role of the mammalian ta
  • PMID 23751205
  • Agonist binding to the GluK5 subunit is sufficient for functional surface expression of heteromeric GluK2/GluK5 kainate receptors.
  • Fisher JL, Housley PR.SourceDepartment of Pharmacology, Physiology and Neuroscience, University of South Carolina School of Medicine, Columbia, SC, 29208, USA,
  • Cellular and molecular neurobiology.Cell Mol Neurobiol.2013 Nov;33(8):1099-108. doi: 10.1007/s10571-013-9976-x. Epub 2013 Aug 23.
  • Trafficking of ionotropic glutamate receptors to the plasma membrane commonly requires occupation of the agonist binding sites. This quality control check does not typically involve receptor activation, as binding by competitive antagonists or to non-functional channels may also permit surface expre
  • PMID 23975096


  • 柑橘機能性成分の中枢神経系に及ぼす作用の解析及び食品素材への展開
  • Extracellular ATP modulates synaptic plasticity induced by activation of metabotropic glutamate receptors in the hippocampus
  • 認知症の予防・治療技術開発の新しい戦略<br/>—天然物を用いたアプローチ—


Dual effect of DL -homocysteine and S -adenosylhomocysteine on brain synthesis of the glutamate receptor antagonist, kynurenic acid JOURNAL OF NEUROSCIENCE RESEARCH, Issue 3 2005 E. Luchowska Abstract Increased ...
1. Ann Neurol. 2004 Apr;55(4):541-9. Glutamate receptor antagonists protect from virus-induced neural degeneration. Nargi-Aizenman JL, Havert MB, Zhang M, Irani DN, Rothstein JD, Griffin DE. W. Harry Feinstone Department of ...



リンク元グルタミン酸受容体遮断薬」「glutamate antagonist」「excitatory amino acid antagonist」「グルタミン酸受容体拮抗薬
関連記事antagonist」「receptor」「glutamate」「glutamate receptor



glutamate receptor antagonistglutamate antagonist

glutamate antagonist」


excitatory amino acid antagonistglutamate receptor antagonist

excitatory amino acid antagonist」


glutamate antagonistglutamate receptor antagonist



glutamate receptor antagonist


  [★] 拮抗薬

WordNet   license wordnet

「a drug that neutralizes or counteracts the effects of another drug」

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「a muscle that relaxes while another contracts; "when bending the elbow the triceps are the antagonist"」

PrepTutorEJDIC   license prepejdic



  [★] 受容体

WordNet   license wordnet

「a cellular structure that is postulated to exist in order to mediate between a chemical agent that acts on nervous tissue and the physiological response」

PrepTutorEJDIC   license prepejdic

「=sense organ / 受信装置」




WordNet   license wordnet

「a salt or ester of glutamic acid」

glutamate receptor」

  [★] グルタミン酸受容体