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出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2015/06/20 11:43:08」(JST)

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  • Clinical pharmacology of paracetamol in neonates: a review.
  • Pacifici GM1, Allegaert K2.
  • Current therapeutic research, clinical and experimental.Curr Ther Res Clin Exp.2014 Dec 12;77:24-30. doi: 10.1016/j.curtheres.2014.12.001. eCollection 2015.
  • Paracetamol is commonly used to control mild-to-moderate pain or to reduce opioid exposure as part of multimodal analgesia, and is the only compound recommended to treat fever in neonates. Paracetamol clearance is lower in neonates than in children and adults. After metabolic conversion, paracetamol
  • PMID 25709719
  • Metabolites identification of bioactive licorice compounds in rats.
  • Wang Q1, Qian Y1, Wang Q1, Yang YF1, Ji S1, Song W1, Qiao X1, Guo DA1, Liang H2, Ye M3.
  • Journal of pharmaceutical and biomedical analysis.J Pharm Biomed Anal.2015 Nov 10;115:515-22. doi: 10.1016/j.jpba.2015.08.013. Epub 2015 Aug 17.
  • Licorice (Glycyrrhiza uralensis Fisch.) is one of the most popular herbal medicines worldwide. This study aims to identify the metabolites of seven representative bioactive licorice compounds in rats. These compounds include 22β-acetoxyl glycyrrhizin (1), licoflavonol (2), licoricidin (3), licoisof
  • PMID 26311472
  • An untargeted metabolomics-driven approach based on LC-TOF/MS and LC-MS/MS for the screening of xenobiotics and metabolites of Zhi-Zi-Da-Huang decoction in rat plasma.
  • Wu H1, Li X1, Yan X1, An L1, Luo K1, Shao M1, Jiang Y1, Xie R1, Feng F2.
  • Journal of pharmaceutical and biomedical analysis.J Pharm Biomed Anal.2015 Nov 10;115:315-22. doi: 10.1016/j.jpba.2015.07.026. Epub 2015 Jul 26.
  • Zhi-Zi-Da-Huang decoction (ZZDHD), a typical traditional Chinese medicine prescription, is widely used in clinical practice for the treatment of alcoholic liver disease. However, due to lack of holistic metabolic research, the active ingredients of ZZDHD have not been fully elucidated. It entails a
  • PMID 26275719


  • Effects of β-Naphthoflavone on Ugt1a6 and Ugt1a7 Expression in Rat Brain
  • UGT Xenobiotic metabolizing activity and genetic evolution in Pinniped species
  • Estimating the Differences of UGT1A1 Activity in Recombinant UGT1A1 Enzyme, Human Liver Microsomes and Rat Liver Microsome Incubation Systems <i>in Vitro</i>


glucuronidation (glōō·k ·rō·n ·dāˑ·sh n), n a phase II detoxification pathway occurring in the liver in which glucuronic acid is conjugated with toxins. ... UGT is an enzyme responsible for the process of glucuronidation, which changes ...
Glucuronidase (beta-glucuronidase): an enzyme that hydrolyzes a glucuronide, destroying glucuronidation, especially that which occurs widely (as in liver and spleen) and hydrolyzes the beta form of a glucuronide The liver ...


Theograndin IGlucuronidation of toxic substances [ edit Glucuronide synthesis made easyOpioid-Induced Hyperalgesia: An Emerging Enzyme-mediated GlucuronidationGeneral mechanism for glucuronidation







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