galanthamine

出典: meddic

ガランタミン

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出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2014/03/26 19:02:26」(JST)

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英文文献

  • Development and in vivo evaluation of novel monolithic controlled release compositions of galantamine hydrobromide as against reservoir technology.
  • Khatavkar UN, Shimpi SL, Kumar KJ, Deo KD.SourceFormulation Research Division, Aurobindo Pharma Limited Research Centre , Bachupally, Quthubullapur, Hyderabad , India.
  • Pharmaceutical development and technology.Pharm Dev Technol.2013 Sep-Oct;18(5):1148-58. doi: 10.3109/10837450.2011.595799. Epub 2011 Jul 20.
  • The objective of this study is to develop and in vivo evaluation of novel monolithic matrix mini tablets approach to control the release of galantamine hydrobromide (GAH) in comparison with desired release profile to the Innovator formulation Razadyne(®) ER capsules. The direct compression method w
  • PMID 21770841
  • Elicitation of galanthamine biosynthesis by Leucojum aestivum liquid shoot cultures.
  • Ivanov I, Georgiev V, Pavlov A.SourceLaboratory of Applied Biotechnologies, The Stephan Angeloff Institute of Microbiology, Bulgarian Academy of Sciences, 139 Ruski Boulevard, Plovdiv 4000, Bulgaria; Department of Organic Chemistry, University of Food Technologies, Plovdiv, 26 Maritza Boulevard, Plovdiv 4002, Bulgaria.
  • Journal of plant physiology.J Plant Physiol.2013 Aug 15;170(12):1122-9. doi: 10.1016/j.jplph.2013.03.017. Epub 2013 May 3.
  • The effects of methyl jasmonate and jasmonic acid on galanthamine production, phenolic acid content and growth of Leucojum aestivum L. shoot culture, cultivated in submerged conditions were investigated. The best time-point for addition of elicitors was during the exponential phase of the culture gr
  • PMID 23648110
  • Natural Products as Sources of New Lead Compounds for the Treatment of Alzheimer's Disease.
  • Huang L, Su T, Li X.SourceInstitute of Drug Synthesis and Pharmaceutical Process, School of Pharmaceutical Sciences, Sun Yat-sen University, Guangzhou 510006, China. lixsh@mail.sysu.edu.cn.
  • Current topics in medicinal chemistry.Curr Top Med Chem.2013 Aug 5. [Epub ahead of print]
  • Alzheimer's disease (AD) is the most prevalent form of dementia and affects approximately 24 million people worldwide. One possible approach for the treatment of this disease is the restoration of the level of acetylcholine (ACh) through the inhibition of acetylcholinesterase (AChE) with reversible
  • PMID 23931437

和文文献

  • Synthesis of demethoxy-lycoraminone
  • Herke Klara,Hazai Laszlo,Dubrovay Zsofia [他]
  • Heterocycles 83(3), 581-589, 2011-03-01
  • NAID 40018281866
  • Total synthesis of (+)- and (-)-galanthamine
  • Kato Tomoaki,Tanimoto Hiroki,Yamada Hisako [他]
  • Heterocycles 82(1), 563-579, 2010-12-31
  • NAID 40017418854

関連リンク

Buy Galanthamine Hydrobromide (CAS 1953-04-4), a competitive and reversible acetylcholinesterase inhibitor, from Santa Cruz Biotechnology. ... Galanthamine Hydrobromide is a competitive and reversible AChE ...
The alkaloid galanthamine is a valuable product from the group of natural anticholinesterase substances. It was the first isolated by Proskurnina and Yakovleva (1952) from Galanthus woronowi Los., fam ... Baraka A, Cozanitis D ...

関連画像

Galanthamine (Reminyl TM )Galanthamine Hydrobromide 99% ingredient galanthamine galanthamineGalanthamine - click for 3D structureGalanthamine HBr Chemical StructureGalanthamine HBr Hydrobromide - Lycoris


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ガランタミン」

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galantamine、(欧)galanthamine
臭化水素酸ガランタミン galantamine hydrobromide
レミニール
抗認知症薬
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  • アセチルコリン阻害作用、ニコチン性アセチルコリン受容体の感受性の亢進作用(アロステリック・モジュレーター)
  • シナプス前膜でアセチルコリン、ノルエピネフリン、セロトニン、グルタミン酸、GABA等の神経伝達物質の放出を促進。
  • 海外の論文ではAD患者に対して3年にわたってかなりの症例数で認知機能を維持するという報告があったり、ドネペジルとの比較でガランタミンの法が認知機能が認知機能の維持効果が高いとされている(週刊 医学会新聞 2011/5/23)




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