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出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2016/08/29 20:54:02」(JST)

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  • Galantamine derivatives with indole moiety: Docking, design, synthesis and acetylcholinesterase inhibitory activity.
  • Atanasova M1, Stavrakov G1, Philipova I2, Zheleva D1, Yordanov N1, Doytchinova I3.
  • Bioorganic & medicinal chemistry.Bioorg Med Chem.2015 Sep 1;23(17):5382-9. doi: 10.1016/j.bmc.2015.07.058. Epub 2015 Jul 29.
  • The inhibitors of acetylcholinesterase are the main therapy against Alzheimer's disease. Among them, galantamine is the best tolerated and the most prescribed drug. In the present study, 41 galantamine derivatives with known acetylcholinesterase inhibitory activities expressed as IC50 were selected
  • PMID 26260334
  • Adverse Drug Reactions Reported With Cholinesterase Inhibitors: An Analysis of 16 Years of Individual Case Safety Reports From VigiBase.
  • Kröger E1, Mouls M2, Wilchesky M3, Berkers M4, Carmichael PH5, van Marum R6, Souverein P4, Egberts T7, Laroche ML8.
  • The Annals of pharmacotherapy.Ann Pharmacother.2015 Aug 31. pii: 1060028015602274. [Epub ahead of print]
  • BACKGROUND: No worldwide pharmacovigilance study evaluating the spectrum of adverse drug reactions (ADRs) induced by cholinesterase inhibitors (ChEI) in Alzheimer's disease has been conducted since their emergence on the market.OBJECTIVE: To describe ChEI related ADRs in Alzheimer's disease (donepez
  • PMID 26324356
  • Galantamine Attenuates Type 1 Diabetes and Inhibits Anti-Insulin Antibodies in Non-Obese Diabetic Mice.
  • Hanes WM1,2, Olofsson PS1, Kwan K1, Hudson LK1, Chavan SS1, Pavlov VA1, Tracey KJ1.
  • Molecular medicine (Cambridge, Mass.).Mol Med.2015 Aug 17. doi: 10.2119/molmed.2015.00142. [Epub ahead of print]
  • Type 1 diabetes in mice is characterized by autoimmune destruction of insulin-producing pancreatic β cells. Disease pathogenesis involves invasion of pancreatic islets by immune cells, including macrophages and T cells, and production of antibodies to self-antigens, including insulin. Activation of
  • PMID 26322849


  • アルツハイマー型認知症に対するガランタミンの使用実態下における安全性および有効性
  • 瀧澤 真奈美,大西 隆,多月 克也 [他]
  • 老年精神医学雑誌 26(3), 285-296, 2015-03
  • NAID 40020418048
  • 症例報告 病名告知によりうつ状態が悪化し,ガランタミンの投与がその改善に有効であったアルツハイマー病の1例
  • 互 健二,品川 俊一郎,加田 博秀 [他]
  • 老年精神医学雑誌 25(11), 1254-1259, 2014-11
  • NAID 40020291224
  • アルツハイマー病の治療 (特集 アセチルコリンと神経疾患 : 100年目の現在地)
  • 品川 俊一郎,繁田 雅弘
  • Brain and nerve : 神経研究の進歩 66(5), 507-516, 2014-05
  • NAID 40020088797


How to use galantamine: Use galantamine as directed by your doctor. Check the label on the medicine for exact dosing instructions. Take galantamine by mouth with the morning and evening meals, unless your doctor tells you ...
Galantamine comes as a tablet, an extended-release (long-acting) capsule, and a solution (liquid) to take by mouth. The tablets and liquid are usually taken twice a day, preferably with the morning and evening meals. The extended ...


from the Red Spider Lily, Galantamine Galantamine generic Life Enhancement galantamine hbr er galantamine hbr er Galantamine: Alzheimer’s treatmentGalantamine Superior to DonepezilGalantamine.svg

拡張検索galantamine hydrobromide



臭化水素酸ガランタミン galantamine hydrobromide

  • アセチルコリン阻害作用、ニコチン性アセチルコリン受容体の感受性の亢進作用(アロステリック・モジュレーター)
  • シナプス前膜でアセチルコリン、ノルエピネフリン、セロトニン、グルタミン酸、GABA等の神経伝達物質の放出を促進。
  • 海外の論文ではAD患者に対して3年にわたってかなりの症例数で認知機能を維持するという報告があったり、ドネペジルとの比較でガランタミンの法が認知機能が認知機能の維持効果が高いとされている(週刊 医学会新聞 2011/5/23)

galantamine hydrobromide」

  [★] 臭化水素酸ガランタミン