WordNet

the atomic process that occurs during a chemical reaction; "he determined unique mechanisms for the photochemical reactions" (同)chemical mechanism
the technical aspects of doing something; "a mechanism of social control"; "mechanisms of communication"; "the mechanics of prose style" (同)mechanics
device consisting of a piece of machinery; has moving parts that perform some function
(philosophy) the philosophical theory that all phenomena can be explained in terms of physical or biological causes
a natural object resembling a machine in structure or function; "the mechanism of the ear"; "the mechanism of infection"

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Protein folding at atomic resolution: analysis of autonomously folding supersecondary structure motifs by nuclear magnetic resonance.

Sborgi L, Verma A, Sadqi M, de Alba E, Muñoz V.SourceCentro de Investigaciones Biológicas, Consejo Superior de Investigaciones Científicas, Madrid, Spain.
Methods in molecular biology (Clifton, N.J.).Methods Mol Biol.2013;932:205-18. doi: 10.1007/978-1-62703-065-6_13.
The study of protein folding has been conventionally hampered by the assumption that all single-domain proteins fold by an all-or-none process (two-state folding) that makes it impossible to resolve folding mechanisms experimentally. Here we describe an experimental method for the thermodynamic anal
PMID 22987355

The small heat-shock protein αB-crystallin uses different mechanisms of chaperone action to prevent the amorphous versus fibrillar aggregation of α-lactalbumin.

Kulig M, Ecroyd H.SourceIllawarra Health and Medical Research Institute and School of Biological Sciences, University of Wollongong, NSW 2522, Australia.
The Biochemical journal.Biochem J.2012 Dec 15;448(3):343-52. doi: 10.1042/BJ20121187.
Stress conditions can destabilize proteins, promoting them to unfold and adopt intermediately folded states. Partially folded protein intermediates are unstable and prone to aggregation down off-folding pathways leading to the formation of either amorphous or amyloid fibril aggregates. The sHsp (sma
PMID 23005341