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「antineoplastic drug used to treat some cancers; can cause loss of hair」

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出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2016/05/16 04:02:17」(JST)

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  • Synthesis and biological activity of salinomycin conjugates with floxuridine.
  • Huczyński A1, Antoszczak M2, Kleczewska N2, Lewandowska M2, Maj E3, Stefańska J4, Wietrzyk J3, Janczak J5, Celewicz L2.
  • European journal of medicinal chemistry.Eur J Med Chem.2015 Mar 26;93:33-41. doi: 10.1016/j.ejmech.2015.01.045. Epub 2015 Jan 27.
  • As part of our program to develop anticancer agents, we have synthesized new compounds, which are conjugates between well-known anticancer drug, floxuridine and salinomycin which is able to selectivity kill cancer stem cells. The conjugates were obtained in two ways i.e. by copper(I) catalysed click
  • PMID 25644674
  • Palladium-mediated dealkylation of N-propargyl-floxuridine as a bioorthogonal oxygen-independent prodrug strategy.
  • Weiss JT1, Carragher NO1, Unciti-Broceta A1.
  • Scientific reports.Sci Rep.2015 Mar 19;5:9329. doi: 10.1038/srep09329.
  • Herein we report the development and biological screening of a bioorthogonal palladium-labile prodrug of the nucleoside analogue floxuridine, a potent antineoplastic drug used in the clinic to treat advanced cancers. N-propargylation of the N3 position of its uracil ring resulted in a vast reduction
  • PMID 25788464
  • Phase II trial of hepatic artery infusional and systemic chemotherapy for patients with unresectable hepatic metastases from colorectal cancer: conversion to resection and long-term outcomes.
  • DʼAngelica MI1, Correa-Gallego C, Paty PB, Cercek A, Gewirtz AN, Chou JF, Capanu M, Kingham TP, Fong Y, DeMatteo RP, Allen PJ, Jarnagin WR, Kemeny N.
  • Annals of surgery.Ann Surg.2015 Feb;261(2):353-60. doi: 10.1097/SLA.0000000000000614.
  • PURPOSE: Evaluate conversion rate of patients with unresectable colorectal-liver metastasis to complete resection with hepatic-arterial infusion plus systemic chemotherapy including bevacizumab (Bev).PATIENTS AND METHODS: Forty-nine patients with unresectable colorectal liver metastases (CRLM) were
  • PMID 24646562


  • Interaction of Intestinal Nucleoside Transporter hCNT2 with Amino Acid Ester Prodrugs of Floxuridine and 2-Bromo-5,6-dichloro-1-β-D-ribofuranosylbenzimidazole(Pharmacology)
  • Phase I/II study of hepatic arterial therapy with floxuridine and dexamethasone in combination with intravenous irinotecan as adjuvant treatment after resection of hepatic metastases from colorectal cancer
  • Quality of life and survival with continuous hepaticaetery floxuridine infusion for colorectal liver metastases


(floks-YOOR-ih-deen) Trade names: FUDR ® Chemocare.com uses generic drug names in all descriptions of drugs. FUDR is the trade name for floxuridine. In some cases, health care professionals may use the trade name ...
Floxuridineとは?goo Wikipedia (ウィキペディア) 。出典:Wikipedia(ウィキペディア)フリー百科事典。 Floxuridineとは - goo Wikipedia (ウィキペディア) gooトップ サイトマップ スタートページに設定 RSS ヘルプ メニューへスキップ 本文へ ...





  [★] 5-フルオロデオキシウリジン



5-fluorodeoxyuridine, FUdR
フロクスウリジン floxuridine, 5-フルオロデオキシウリジン 5-fluoro-2′-deoxyuridine 5-FUdR

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