女性尿道下裂
WordNet
- for or pertaining to or composed of women or girls; "the female lead in the play"; "a female chorus"
- an animal that produces gametes (ova) that can be fertilized by male gametes (spermatozoa)
- a person who belongs to the sex that can have babies (同)female person
- characteristic of or peculiar to a woman; "female sensitiveness"; "female suffrage" (同)distaff
- being the sex (of plant or animal) that produces fertilizable gametes (ova) from which offspring develop; "a female heir"; "female holly trees bear the berries"
- an abnormal condition in males in which the urethra opens on the under surface of the penis
PrepTutorEJDIC
- (動植物について)『雌の』 / (特に性を区別して)『女の』,女性の / (ねじ・差し込みなど)雌の / 『雌』;(性別上の)『女性』 / 《話》女性,婦人
UpToDate Contents
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English Journal
- Ovotesticular disorder of sexual development due to 47,XYY/46,XY/45,X mixed gonadal dysgenesis in a phenotypic male presenting as cyclical haematuria: clinical presentation and assessment of long-term outcomes.
- Dutta D, Shivaprasad KS, Das RN, Ghosh S, Chatterjee U, Chowdhury S, Dasgupta R.Author information Department of Endocrinology & Metabolism, IPGMER & SSKM Hospital, Kolkata, India.AbstractOvotesticular disorder of sexual differentiation (OTDSD) is a rare cause of disorder of sexual differentiation predominantly having 46,XX karyotype, female phenotype and ambiguous genitalia. We report a 15-year-old having male body habitus, axillary and pubic hair, well-developed penis and right-descended testis with history of penoscrotal hypospadias correction, presenting with three episodes of cyclical haematuria, who biochemically had normal serum testosterone (338 ng dl(-1) ) which increased following hCG stimulation (614 ng dl(-1) ), elevated estradiol (17.35 pg ml(-1) ) along with elevated luteinising hormone (11.3 mIU l(-1) ) and follicle-stimulating hormone (31 mIU l(-1) ). Ultrasonography followed by micturating cystourethrogram and cystoscopy confirmed the presence of prostate, uterus, cervix and vagina draining into the urogenital sinus continuing till the penile urethra and left intra-abdominal gonad. Patient underwent hysterectomy and left gonadectomy. Histopathologic study of resected gonad confirmed presence of ovotestis. Low estradiol (1.2 pg ml(-1) ) following gonadectomy confirmed the ovotestis origin of estradiol. Chromosomal analysis revealed complex karyotype predominant being 47,XYY (50%) followed by 46,XY (26%) and 45,X (24%). This is perhaps the first report of 47,XYY/46,XY/45,X causing OTDSD in a phenotypic male.
- Andrologia.Andrologia.2014 Mar;46(2):191-3. doi: 10.1111/and.12048. Epub 2012 Nov 19.
- Ovotesticular disorder of sexual differentiation (OTDSD) is a rare cause of disorder of sexual differentiation predominantly having 46,XX karyotype, female phenotype and ambiguous genitalia. We report a 15-year-old having male body habitus, axillary and pubic hair, well-developed penis and right-des
- PMID 23163819
- Clinical characteristics, cytogenetic and molecular findings in patients with disorders of sex development.
- Tian L, Chen M, Peng JH, Zhang JW, Li L.Author information Department of Blood Transfusion, Zhongnan Hospital of Wuhan University, Wuhan, 430071, China, litian1971@sina.com.AbstractThe clinical characteristics of patients with disorders of sex development (DSD), and the diagnostic values of classic cytogenetic and molecular genetic assays for DSD were investigated. In the enrolled 56 cases, there were 9 cases of 46,XY DSD, 6 cases of Turner syndrome (TS), one case of Super female syndrome, 25 cases of Klinefelter syndrome, 14 cases of 46,XX DSD, and one case of autosomal balanced rearrangements with hypospadias. The diagnosis of sex was made through physical examination, cytogenetic assay, ultrasonography, gonadal biopsy and hormonal analysis. PCR was used to detect SRY, ZFX, ZFY, DYZ3 and DYZ1 loci on Y and X chromosomes respectively. The DSD patients with the same category had similar clinical characteristics. The karyotypes in peripheral blood lymphocytes of all patients were identified. PCR-based analysis showed presence or absence of the X/Y-linked loci in several cases. Of the 9 cases of 46,XY DSD, 6 were positive for SRY, 9 for ZFX/ZFY, 9 for DYZ3 and 8 for DYZ1 loci. Of the 6 cases of TS, only 1 case with the karyotype of 45,X,/46,XX/46,XY was positive for all 5 loci. Of the 25 cases of Klinefelter syndrome, all were positive for all 5 loci. In one case of rare Klinefelter syndrome variants azoospermia factor (AZF) gene detection revealed the loss of the AZFa+AZFb region. In 14 cases of 46,XX DSD, 7 cases were positive for SRY, 14 for ZFX, 7 for ZFY, 7 for ZYZ3, and 5 for DYZ1. PCR can complement and also confirm cytogenetic studies in the diagnosis of sex in cases of DSD.
- Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban.J Huazhong Univ Sci Technolog Med Sci.2014 Feb;34(1):81-6. doi: 10.1007/s11596-014-1235-y. Epub 2014 Feb 6.
- The clinical characteristics of patients with disorders of sex development (DSD), and the diagnostic values of classic cytogenetic and molecular genetic assays for DSD were investigated. In the enrolled 56 cases, there were 9 cases of 46,XY DSD, 6 cases of Turner syndrome (TS), one case of Super fem
- PMID 24496683
- [Female hypospadias diagnosed in an adolescent].
- Chemaou A, Lasry F, Nejdioui Z, Eizmmouri M, Sibai H.Author information Service pédiatrie 3, unité de néphrologie pédiatrique, Casablanca, Maroc. Electronic address: docteurchemaou@yahoo.fr.AbstractHypospadias is an exceptional congenital anomaly in females, contrasted with hypospadias in males, which is much more common. In girls, the diagnosis is made only a few months after birth or later. Female hypospadias involves total or partial agenesis of the urethrovaginal septum, resulting in urinary drainage into the genital tract. Rarely isolated, it is usually associated with other urogenital or spinal anomalies. Treatment is based on surgical urethral reconstruction. We report the case of a 13-year-old girl living in a rural area who had no specific medical history. The girl was admitted with anuria, renal failure, and hypertension. After physical examination and investigations, the diagnosis was female hypospadias, with neurogenic bladder due to sacral agenesis. Surgical treatment consisted of urethral meatus apicalization, with meatoplasty for intermittent catheterization via the urethra. Blood pressure and renal function normalized.
- Archives de pédiatrie : organe officiel de la Sociéte française de pédiatrie.Arch Pediatr.2013 Dec;20(12):1314-6. doi: 10.1016/j.arcped.2013.09.011. Epub 2013 Oct 30.
- Hypospadias is an exceptional congenital anomaly in females, contrasted with hypospadias in males, which is much more common. In girls, the diagnosis is made only a few months after birth or later. Female hypospadias involves total or partial agenesis of the urethrovaginal septum, resulting in urina
- PMID 24182665
Japanese Journal
- Fertility preservation in a family with a novel NR5A1 mutation
- Fertility preservation in a family with a novel NR5A1 mutation
Related Links
- hypospadias [hi″po-spa´de-as] a developmental anomaly in which the urethra opens inferior to its normal position, usually in males with the opening on the underside of the penis or on the perineum. In perineal hypospadias the ...
- A case of proximal female hypospadias with urethral atresia is reported, and a nosological definition of this rare congenital anomaly is proposed. An attempt to ... Abstract A case of proximal female hypospadias with urethral atresia ...
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- 関
- female sex、females、glycogen synthase kinase 3 beta、male、woman、women