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the univalent hydrocarbon radical C2H5 derived from ethane by the removal of one hydrogen atom (同)ethyl_group, ethyl radical

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出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2015/12/05 21:45:55」(JST)

Ethyl biscoumacetate is a vitamin K antagonist.

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Pitrák V1, Hadacová I, Hochová I, Hoch J.
Rozhledy v chirurgii : měsíčník Československé chirurgické společnosti.Rozhl Chir.2001 Jun;80(6):290-3.
Chronic anticoagulant treatment is administered mostly for cardiological reasons. Cumarin derivatires are used in the majority of cases (Warfarin, Pelentan). It is necessary to monitor this treatment regularly and to control the dose according to the INR value. Different complications can occur; the
PMID 11482149

[Use of hypoprothrombinemia provocation test for early diagnosis of liver disease caused by harmful environmental agents].

Prazanowski M1, Piłacik B, Lutz W.
Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego.Pol Merkur Lekarski.1998 Mar;4(21):154-7.
The aim of this work has been to assess the feasibility of using Prothrombin Time (PT) Assay before and after administration of Pelentan (Hypoprothrombinemia Provocation (HPP) Test) for early detection of subclinical toxic hepatic injuries. The proposed modification of PT Assay is based on the obser
PMID 9640069

Pharmacokinetics of ethyl biscoumacetate and its metabolite 7-hydroxy ethyl biscoumacetate in healthy volunteers.

Perlík F1, Patzelová V.
International journal of clinical pharmacology and therapeutics.Int J Clin Pharmacol Ther.1994 Nov;32(11):622-4.
Disposition kinetics of ethyl biscoumacetate and its metabolite 7-hydroxy ethyl biscoumacetate were evaluated in ten healthy volunteers, after a single 300 mg oral dose of ethyl biscoumacetate. Serum concentrations of parent compound and its metabolite were measured by HPLC. The maximum serum ethyl
PMID 7874379

Ethyl biscoumacetate
Systematic (IUPAC) name
	3,3-(ethyl acetate-methylene)-bis(4-hydroxycoumarin)
Identifiers
CAS Number	548-00-5
ATC code	B01AA08
PubChem	CID: 11047
DrugBank	DB08794
ChemSpider	10444159
UNII	08KL644731
KEGG	D07131
ChEMBL	CHEMBL2106261
Chemical data
Formula	C22H16O8
Molecular mass	408.358 g/mol
	InChI InChI=1S/C22H16O8/c1-2-28-20(25)15(16-18(23)11-7-3-5-9-13(11)29-21(16)26)17-19(24)12-8-4-6-10-14(12)30-22(17)27/h3-10,15,23-24H,2H2,1H3 ; Key:JCLHQFUTFHUXNN-UHFFFAOYSA-N ;
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