エチルビスクムアセテート
WordNet
- the univalent hydrocarbon radical C2H5 derived from ethane by the removal of one hydrogen atom (同)ethyl_group, ethyl radical
PrepTutorEJDIC
- エチル / エチルの
Wikipedia preview
出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2015/12/05 21:45:55」(JST)
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Ethyl biscoumacetate
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Systematic (IUPAC) name |
3,3-(ethyl acetate-methylene)-bis(4-hydroxycoumarin)
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Identifiers |
CAS Number |
548-00-5 N |
ATC code |
B01AA08 |
PubChem |
CID: 11047 |
DrugBank |
DB08794 Y |
ChemSpider |
10444159 Y |
UNII |
08KL644731 N |
KEGG |
D07131 Y |
ChEMBL |
CHEMBL2106261 N |
Chemical data |
Formula |
C22H16O8 |
Molecular mass |
408.358 g/mol |
InChI
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InChI=1S/C22H16O8/c1-2-28-20(25)15(16-18(23)11-7-3-5-9-13(11)29-21(16)26)17-19(24)12-8-4-6-10-14(12)30-22(17)27/h3-10,15,23-24H,2H2,1H3 Y
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Key:JCLHQFUTFHUXNN-UHFFFAOYSA-N Y
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N (what is this?) (verify) |
Ethyl biscoumacetate is a vitamin K antagonist.
References
- The Merck Index, 12th Edition. 3818
Types of coumarins
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Aglycones |
- Aesculetin
- Ferujol
- Umbelliferone
O-Methylated
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- Fraxetin
- Herniarin (7-O-Methylumbelliferone)
- Osthol
- Scopoletin (6-Methoxyumbelliferone)
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glycosides |
- Aesculin (Esculetin 6-O-glucoside)
- Fraxin (Fraxetin glucoside)
- Skimmin (Umbelliferone 7-O-glucoside)
- Scopolin
- Umbelliferone 7-apiosylglucoside
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derivatives |
Furanocoumarins
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Aglycones
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- Angelicin
- Marmesin
- Psoralen
- Vaginol
- Xanthotoxol (8-Hydroxypsoralen)
O-Methylated
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- Bergapten (5-methoxypsoralen)
- Isopimpinellin (5,8-Dimethoxypsoralene)
- Methoxsalen (8-Methoxypsoralen)
- Trioxsalen (2,5,9-Trimethylpsoralen)
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Furanocoumarin glycosides
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- Apterin (vaginol glucoside)
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Meroterpene furanocoumarin ether
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- Auraptene
- Bergamottin
- Imperatorin
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Oligomers |
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Synthetic |
- Acenocoumarol
- Coumatetralyl
- Ensaculin
- Ethyl biscoumacetate
- 4-Hydroxycoumarins
- Hymecromone
- Phenprocoumon
- Warfarin
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UpToDate Contents
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English Journal
- [Serious surgical complications associated with chronic anticoagulant therapy].
- Pitrák V1, Hadacová I, Hochová I, Hoch J.
- Rozhledy v chirurgii : měsíčník Československé chirurgické společnosti.Rozhl Chir.2001 Jun;80(6):290-3.
- Chronic anticoagulant treatment is administered mostly for cardiological reasons. Cumarin derivatires are used in the majority of cases (Warfarin, Pelentan). It is necessary to monitor this treatment regularly and to control the dose according to the INR value. Different complications can occur; the
- PMID 11482149
- [Use of hypoprothrombinemia provocation test for early diagnosis of liver disease caused by harmful environmental agents].
- Prazanowski M1, Piłacik B, Lutz W.
- Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego.Pol Merkur Lekarski.1998 Mar;4(21):154-7.
- The aim of this work has been to assess the feasibility of using Prothrombin Time (PT) Assay before and after administration of Pelentan (Hypoprothrombinemia Provocation (HPP) Test) for early detection of subclinical toxic hepatic injuries. The proposed modification of PT Assay is based on the obser
- PMID 9640069
- Pharmacokinetics of ethyl biscoumacetate and its metabolite 7-hydroxy ethyl biscoumacetate in healthy volunteers.
- Perlík F1, Patzelová V.
- International journal of clinical pharmacology and therapeutics.Int J Clin Pharmacol Ther.1994 Nov;32(11):622-4.
- Disposition kinetics of ethyl biscoumacetate and its metabolite 7-hydroxy ethyl biscoumacetate were evaluated in ten healthy volunteers, after a single 300 mg oral dose of ethyl biscoumacetate. Serum concentrations of parent compound and its metabolite were measured by HPLC. The maximum serum ethyl
- PMID 7874379
Related Links
- coumarins: Acenocoumarol · Coumatetralyl · Dicoumarol; Ethyl biscoumacetate; Phenprocoumon · Warfarin#; 1,3-Indandiones: Clorindione · Diphenadione · Phenindione; other: Tioclomarol · Factor Xa inhibitors (with some II inhibition) ...
- 8 Oct 2010 ... Identification. Name, Ethyl biscoumacetate. Accession Number, DB08794. Type, small molecule. Groups. Description. Ethyl biscoumacetate is a courmarin that is used as an anticoagulant. It has actions similar to those of ...
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