WordNet

a substance that exerts some force or effect
a businessman who buys or sells for another in exchange for a commission (同)factor, broker
any agent or representative of a federal agency or bureau (同)federal agent
a representative who acts on behalf of other persons or organizations
an active and efficient cause; capable of producing a certain effect; "their research uncovered new disease agents"

PrepTutorEJDIC

全文を閲覧するには購読必要です。 To read the full text you will need to subscribe.

Fatty acid synthase is a metabolic marker of cell proliferation rather than malignancy in ovarian cancer and its precursor cells.

Veigel D1, Wagner R, Stübiger G, Wuczkowski M, Filipits M, Horvat R, Benhamú B, López-Rodríguez ML, Leisser A, Valent P, Grusch M, Hegardt FG, García J, Serra D, Auersperg N, Colomer R, Grunt TW.
International journal of cancer. Journal international du cancer.Int J Cancer.2015 May 1;136(9):2078-90. doi: 10.1002/ijc.29261. Epub 2014 Nov 3.
Ovarian cancer (OC) is caused by genetic aberrations in networks that control growth and survival. Importantly, aberrant cancer metabolism interacts with oncogenic signaling providing additional drug targets. Tumors overexpress the lipogenic enzyme fatty acid synthase (FASN) and are inhibited by FAS
PMID 25302649

An evaluation of a human stem cell line to identify risk of developmental neurotoxicity with antiepileptic drugs.

Cao WS1, Livesey JC2, Halliwell RF3.
Toxicology in vitro : an international journal published in association with BIBRA.Toxicol In Vitro.2015 Apr;29(3):592-9. doi: 10.1016/j.tiv.2015.01.010. Epub 2015 Jan 27.
Determination of the impact of a drug on human brain development relies instead on surrogate animal studies. Here we have exploited the human stem cell line, TERA2.cl.SP12 to differentiate into neurons and addressed their value as an in vitro model to evaluate the risk of developmental neurotoxicity
PMID 25637331

Differentiation of bacterial and non-bacterial community-acquired pneumonia by thin-section computed tomography.

Ito Isao,Ishida Tadashi,Togashi Kaori,Niimi Akio,Koyama Hiroshi,Ishimori Takayoshi,Kobayashi Hisataka,Mishima Michiaki
European journal of radiology 72(3), 388-395, 2009-12
… BACKGROUND AND OBJECTIVE: The management of community-acquired pneumonia (CAP) depends, in part, on the identification of the causative agents. … The objective of this study was to determine the potential of thin-section computed tomography (CT) in differentiating bacterial and non-bacterial pneumonia. …
NAID 120002576696

Differentiation-associated alteration in sensitivity to apoptosis induced by (-)-epigallocatechin-3-O-gallate in HL-60 cells

Okada Norihisa,Tanabe Hiroki,Tazoe Hideaki,Ishigami Yoko,Fukutomi Ryuuta,Yasui Kensuke,Isemura Mamoru
Biomedical Research 30(4), 201-206, 2009
… HL-60 cells treated with three differentiating agents were found to be resistant to EGCG-mediated apoptosis as compared with undifferentiated cells. …
NAID 130004903753

佐々木彰一
東京女子医科大学雑誌 78(臨時増刊号), E19-E25, 2008-02-25
… Typical amyotrophlc lateral sclerosis (ALS)/motor neuron disease (MND) is not hard to diagnose, but we may face some difficulties in differentiating between atypical forms of ALS/MND which account for about 20% and other non-ALS diseases. … Clinical trials of new therapeutic agents have been performed, on the assumption that patients with ALS/MND have the same underlying etiology, addressing the heterogeneous population of the patients under a single diagnostic category. …
NAID 110007524776

関: agonist、agonistic、attorney、delegate、drug、etiologic agent、fomes、fomites、mediator、pathogen、pathogenic、pharmaceutical preparation、vector、vehicle